Glucocorticoid effects on NF-κB binding in the transcription of the ICAM-1 gene

Biochemical and Biophysical Research Communications

Volumn 273, Issue 3, 2000, Pages 1008-1014

  Liden, Johan ^a   Rafter, Ingalill ^a   Truss, Mathias ^b   Gustafsson, Jan Åke ^a   Okret, Sam ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Anti inflammation; Glucocorticoid receptor; In vivo footprinting; NF B; U937 cells

Indexed keywords

GLUCOCORTICOID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL STRAIN U937; DNA BINDING; DNA FOOTPRINTING; GENETIC TRANSCRIPTION; PRIORITY JOURNAL; PROTEIN CONFORMATION;

EID: 0034647929     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.3079     Document Type: Article

References (42)

1. Cato A. C. B., Wade E. Molecular mechanisms of anti-inflammatory action of glucocorticoids. BioEssays. 18:1996;371-378.
2. Ray A., Prefontaine K. E. Physical association and functional antagonism between the p65 subunit of transcription factor NF-κB and the glucocorticoid receptor. Proc. Natl. Acad. Sci. USA. 91:1994;752-756.
3. Scheinman R. I., Gualberto A., Jewell C. M., Cidlowski J. A., Baldwin A. S. Jr. Characterization of mechanisms involved in transrepression of NF-κB by activated glucocorticoid receptors. Mol. Cell. Biol. 15:1995;943-953.
4. Caldenhoven E., Liden J., Wissink S., Van de Stolpe A., Raaijmakers J., Koenderman L., Okret S., Gustafsson J.-Å., Van der Saag P. T. Negative cross-talk between RelA and the glucocorticoid receptor: A possible mechanism for the antiinflammatory action of glucocorticoids. Mol. Endocrinol. 9:1995;401-412.
5. Liden J., Delaunay F., Rafter I., Gustafsson J.-Å., Okret S. A new function for the C-terminal zinc finger of the glucocorticoid receptor. Repression of RelA transactivation. J. Biol. Chem. 272:1997;21467-21472.
6. Traenckner E. B., Pahl H. L., Henkel T., Schmidt K. N., Wilk S., Baeuerle P. A. Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli. EMBO J. 14:1995;2876-2883.
7. Baeuerle P. A., Henkel T. Function and activation of NF-kappa B in the immune system. Annu. Rev. Immunol. 12:1994;141-179.
8. Alkalay I., Yaron A., Hatzubai A., Orian A., Ciechanover A., Ben-Neriah Y. Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway. Proc. Natl. Acad. Sci. USA. 92:1995;10599-10603.
9. Laudet V., Gronemeyer H. Transcription Factors 3: Nuclear receptors. Sheterline. Protein Profile. 1995;1173-1308 Academic Press, London.
10. Carlstedt-Duke J., Wright A., Göttlicher M., Okret S., Gustafsson J.-Å. Molecular mechanisms of hormone action: Regulation of target cell function by the steroid hormone supergene family. Felig P., Baxter G. D., Frohman L. A. Endocrinology and Metabolism. 1995;169-199 McGraw-Hill Inc.
11. Akerblom I. E., Mellon P. L. Repression of gene expression by steroid and thyroid hormones: Molecular mechanisms, cellular functions, clinical abnormalities. Parker M. G. Nuclear Hormone Receptors. 1991;175-196 Academic Press, New York.
12. Drouin J., Sun Y. L., Chamberland M., Gauthier Y., De Lean A., Nemer M., Schmidt T. J. Novel glucocorticoid receptor complex with DNA element of the hormone-repressed POMC gene. EMBO J. 12:1993;145-156.
13. Sakai D. D., Helm S., Carlstedt-Duke J., Gustafsson J.-Å., Rottman F. M., Yamamoto K. R. Hormone-mediated repression: A negative glucocorticoid response element from the bovine prolactin gene. Genes Dev. 2:1988;1144-1154.
14. Strömstedt P. E., Poellinger L., Gustafsson J.-Å., Carlstedt-Duke J. The glucocorticoid receptor binds to a sequence overlapping the TATA box of the human osteocalcin promoter: A potential mechanism for negative regulation. Mol. Cell. Biol. 11:1991;3379-3383.
15. Meyer T., Gustafsson J.-Å., Carlstedt-Duke J. Glucocorticoid-dependent transcriptional repression of the osteocalcin gene by competitive binding at the TATA box. DNA Cell Biol. 16:1997;919-927.
16. Subramaniam N., Cairns W., Okret S. Studies on the mechanism of glucocorticoid-mediated repression from a negative glucocorticoid response element from the bovine prolactin gene [published erratum appears in DNA Cell Biol. 1997 May; 16(5):670]. DNA Cell Biol. 16:1997;153-163.
17. Schmitz M. L., Stelzer G., Altmann H., Meisterernst M., Baeuerle P. A. Interaction of the COOH-terminal transactivation domain of p65 NF-kappa B with TATA-binding protein, transcription factor IIB, and coactivators. J. Biol. Chem. 270:1995;7219-7226.
18. Schüle R., Rangarajan P., Kliewer S., Ransone L. J., Bolado J., Yang N., Verma I. M., Evans R. M. Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor. Cell. 62:1990;1217-1226.
19. Jonat C., Rahmsdorf H. J., Park K. K., Cato A. C., Gebel S., Ponta H., Herrlich P. Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone. Cell. 62:1990;1189-1204.
20. Yang-Yen H. F., Chambard J. C., Sun Y. L., Smeal T., Schmidt T. J., Drouin J., Karin M. Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction. Cell. 62:1990;1205-1215.
21. Mukaida N., Morita M., Ishikawa Y., Rice N., Okamoto S., Kasahara T., Matsushima K. Novel mechanism of glucocorticoid-mediated gene repression. Nuclear factor-kappa B is target for glucocorticoid-mediated interleukin 8 gene repression. J. Biol. Chem. 269:1994;13289-13295.
22. Auphan N., DiDonato J. A., Rosette C., Helmberg A., Karin M. Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of IκB synthesis. Science. 270:1995;286-290.
23. Scheinman R. I., Cogswell P. C., Lofquist A. K., Baldwin A. S. Jr. Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids. Science. 270:1995;283-286.
24. Van de Stolpe A., Caldenhoven E., Stade B. G., Koenderman L., Raaijmakers J. A., Johnson J. P., Van der Saag P. T. 12-O-tetradecanoylphorbol-13-acetate and tumor necrosis factor alpha-mediated induction of intercellular adhesion molecule-1 is inhibited by dexamethasone. Functional analysis of the human intercellular adhesion molecular-1 promoter. J. Biol. Chem. 269:1994;6185-6192.
25. Schreiber E., Matthias P., Muller M. M., Schaffner W. Rapid detection of octamer binding proteins with 'mini-extracts,' prepared from a small number of cells. Nucleic Acids Res. 17:1989;6418-6419.
26. Laird P. W., Zijderveld A., Linders K., Rudnicki M. A., Jaenisch R., Berns A. Simplified mammalian DNA isolation procedure. Nucleic Acids Res. 19:1991;4293.
27. Mueller P. R., Wold B. In vivo footprinting of a muscle specific enhancer by ligation mediated PCR. Science. 246:1989;780-786.
28. Zwicker J., Lucibello F. C., Wolfraim L. A., Gross C., Truss M., Engeland K., Muller R. Cell cycle regulation of the cyclin A, cdc25C, and cdc2 genes is based on a common mechanism of transcriptional repression. EMBO J. 14:1995;4514-4522.
29. Rein T., Muller M., Zorbas H. In vivo. 22:1994;3033-3037.
30. Reichardt H. M., Kaestner K. H., Tuckermann J., Kretz O., Wessely O., Bock R., Gass P., Schmid W., Herrlich P., Angel P., Schutz G. DNA binding of the glucocorticoid receptor is not essential for survival. Cell. 93:1998;531-541.
31. Kleinert H., Euchenhofer C., Ihrig-Biedert I., Forstermann U. Glucocorticoids inhibit the induction of nitric oxide synthase II by down-regulating cytokine-induced activity of transcription factor nuclear factor-kappa B. Mol. Pharm. 49:1996;15-21.
32. Ohtsuka T., Kubota A., Hirano T., Watanabe K., Yoshida H., Tsurufuji M., Iizuka Y., Konishi K., Tsurufuji S. Glucocorticoid-mediated gene suppression of rat cytokine-induced neutrophil chemoattractant CINC/gro, a member of the interleukin-8 family, through impairment of NF-κB activation. J. Biol. Chem. 271:1996;1651-1659.
33. Brostjan C., Anrather J., Csizmadia V., Stroka D., Soares M., Bach F. H., Winkler H. Glucocorticoid-mediated repression of NF-Kappa-B activity in endothelial cells does not involve induction of I-Kappa-B-alpha synthesis. J. Biol. Chem. 271:1996;19612-19616.
34. Wissink S., van Heerde E. C., vand der Burg B., van der Saag P. T. A dual mechanism mediates repression of NF-kappaB activity by glucocorticoids. Mol. Endocrinol. 12:1998;355-363.
35. Heck S., Bender K., Kullmann M., Gottlicher M., Herrlich P., Cato A. C. I kappaB alpha-independent downregulation of NF-kappaB activity by glucocorticoid receptor. EMBO J. 16:1997;4698-4707.
36. De Bosscher K., Schmitz M. L., Vanden Berghe W., Plaisance S., Fiers W., Haegeman G. Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves directinterference with transactivation. Proc. Natl. Acad. Sci. USA. 94:1997;13504-13509.
37. Adcock I. M., Brown C. R., Barnes P. J. Tumour necrosis factor alpha causes retention of activated glucocorticoid receptor within the cytoplasm of A549 cells. Biochem. Biophys. Res. 225:1996;545-550.
38. Algarte M., Lecine P., Costello R., Plet A., Olive D., Imbert J. In vivo. 14:1995;5060-5072.
39. König H., Ponta H., Rahmsdorf H. J., Herrlich P. Interference between pathway-specific transcription factors: Glucocorticoids antagonize phorbol ester-induced AP-1 activity without altering AP-1. EMBO J. 11:1992;2241-2246.
40. Guermah M., Malik S., Roeder R. G. Involvement of TFIID and USA components in transcriptional activation of the human immunodeficiency virus promoter by NF-kappa-B and Sp1. Mol. Cell. Biol. 18:1998;3234-3244.
41. Zhong H. H., Voll R. E., Ghosh S. Phosphorylation of NF-kappa-B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300. Mol. Cell. 1:1998;661-671.
42. Sheppard K. A., Phelps K. M., Williams A. J., Thanos D., Glass C. K., Rosenfeld M. G., Gerritsen M. E., Collins T. Nuclear integration of glucocorticoid receptor and nuclear factor-kappaB signaling by CREB-binding protein and steroid receptor coactivator-1. J. Biol. Chem. 273:1998;29291-29294.