The amino-terminal domain of apolipoprotein B does not undergo retrograde translocation from the endoplasmic reticulum to the cytosol. Proteasomal degradation of nascent apolipoprotein B begins at the carboxyl terminus of the protein, while apolipoprotein B is still in its original translocon

Journal of Biological Chemistry

Volumn 275, Issue 41, 2000, Pages 32003-32010

  Liang, Jun Shan ^a   Wu, Xinye ^b   Fisher, Edward A ^b   Ginsberg, Henry N ^a  

^a Columbia University ^*  (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; APOLIPOPROTEIN B; APOLIPOPROTEIN B100; APOLIPOPROTEIN B42; HEMAGGLUTININ; MONOCLONAL ANTIBODY; MYC PROTEIN; N ACETYLLEUCYLNORLEUCINAL; PROTEINASE K; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEPG2; CHO CELL; CONTROLLED STUDY; CYTOSOL; ENDOPLASMIC RETICULUM; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; INTRACELLULAR TRANSPORT; ISOTOPE LABELING; LIPOPROTEIN METABOLISM; MICROSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN TRANSPORT;

EID: 0034644688     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M004646200     Document Type: Article

References (43)