Bisanthraquinone glycosides of Hypericum perforatum with binding inhibition to CRH-1 receptors

Phytochemistry

Volumn 55, Issue 8, 2000, Pages 941-947

  Wirz, A ^a   Simmen, U ^b   Heilmann, J ^a   Calis I ^c   Meier, B ^d   Sticher, O ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

^c HACETTEPE UNIVERSITY   (Turkey)

^d Zeller AG   (Switzerland)

Author keywords

Bisanthraquinone glycosides; CRH 1 receptor; Hypericaceae; Hypericum perforatum; R ( ) skyrin 6 O glucopyran oside; S (+) skyrin 6 O arabinofuranosid e; S (+) skyrin 6 O glucopyranoside; S (+) skyrin 6 O xylopyranoside

Indexed keywords

ALCOHOL; ANTHRAQUINONE DERIVATIVE; BISANTHRAQUINONE GLYCOSIDE; CORTICOTROPIN RELEASING FACTOR RECEPTOR; CRF RECEPTOR TYPE 1; GLYCOSIDE; HYPERICUM; HYPERICUM PERFORATUM; PEPTIDE; PLANT EXTRACT; PYRANOSIDE; RECEPTORS, CORTICOTROPIN RELEASING HORMONE; SAUVAGINE; SKYRIN 6 O BETA ALPHA ARABINOFURANOSIDE; SKYRIN 6 O BETA GLUCOPYRANOSIDE; SKYRIN 6 O BETA XYLOPYRANOSIDE; UNCLASSIFIED DRUG; VASODILATOR AGENT; WATER;

ACETYLATION; ARTICLE; BINDING COMPETITION; CIRCULAR DICHROISM; CONFORMATION; DRUG ACETYLATION; DRUG EFFECT; DRUG HYDROLYSIS; DRUG INTERACTION; DRUG ISOLATION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; EXTRACTION; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RECEPTOR BLOCKING; STEREOCHEMISTRY; STEREOISOMERISM;

ACETYLATION; BINDING, COMPETITIVE; DRUG INTERACTIONS; HYPERICUM; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; PEPTIDES; PLANTS, MEDICINAL; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; VASODILATOR AGENTS;

CLUSIACEAE; HYPERICUM; HYPERICUM PERFORATUM;

EID: 0034642222     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9422(00)00305-8     Document Type: Article

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