Labelling of CRF1 and CRF2 receptors using the novel radioligand, [3H]-urocortin

Neuropharmacology

Volumn 36, Issue 10, 1997, Pages 1439-1446

  Gottowik, J ^a   Goetschy, V ^a   Henriot, S ^a   Kitas, E ^a   Fluhman, B ^a   Clerc, R G ^a   Moreau, J L ^a   Monsma, F J ^a   Kilpatrick, G J ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

3H urocortin; CRF; CRF1; CRF2; CRH; Receptors

Indexed keywords

[3 (2 BROMO 4 ISOPROPYLPHENYL) 5 METHYL 3H [1,2,3]TRIAZOLO[4,5 D]PYRIMIDIN 7 YL]BIS(2 METHOXYETHYL)AMINE; BUTYL[2,5 DIMETHYL 7 (2,4,6 TRIMETHYLPHENYL) 7H PYRROLO[2,3 D]PYRIMIDIN 4 YL]ETHYLAMINE; CORTICOTROPIN RELEASING FACTOR; CORTICOTROPIN RELEASING FACTOR ANTAGONIST; CORTICOTROPIN RELEASING FACTOR RECEPTOR; N BUTYL N [2,5 DIMETHYL 7 (2,4,6 TRIMETHYLPHENYL) 7H PYRROLO[2,3 D]PYRIMIDIN 4 YL] N ETHYLAMINE; RECEPTOR SUBTYPE; SAUVAGINE; SC 241; UNCLASSIFIED DRUG; UROCORTIN; UROTENSIN I; CRF RECEPTOR TYPE 1; CRF RECEPTOR TYPE 2;

ANIMAL TISSUE; ARTICLE; CEREBELLUM; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; HORMONE RECEPTOR INTERACTION; ISOTOPE LABELING; LIGAND BINDING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; AMINO ACID SEQUENCE; ANIMAL; BINDING COMPETITION; DRUG EFFECT; GENETICS; HUMAN; KINETICS; METABOLISM; MOLECULAR GENETICS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; BINDING, COMPETITIVE; CEREBELLUM; CORTICOTROPIN-RELEASING HORMONE; HUMANS; KINETICS; MALE; MOLECULAR SEQUENCE DATA; RATS; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0030608646     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(97)00098-1     Document Type: Article

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