Mutations in the catalytic domain of prohormone convertase 2 result in decreased binding to 7B2 and loss of inhibition with 7b2 C-terminal peptide

Journal of Biological Chemistry

Volumn 275, Issue 19, 2000, Pages 14667-14677

  Apletalina, Ekaterina V ^a   Muller, Laurent ^a,b   Lindberg, Iris ^a,c  

^a LOUISIANA STATE UNIV HLTH SCI C   (United States)

^b INSERM   (France)

^c LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERMEDIN; FURIN; HORMONE PRECURSOR; NEUROPEPTIDE; PEPTIDE; PROENKEPHALIN; SUBTILISIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CATALYSIS; CHO CELL; CONTROLLED STUDY; ENZYME SPECIFICITY; IMMUNOPRECIPITATION; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN;

ALPHA-MSH; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CATALYTIC DOMAIN; CELL LINE; CULTURE MEDIA, CONDITIONED; DNA PRIMERS; ENKEPHALINS; ENZYME INHIBITORS; HUMANS; HYDROLYSIS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; NERVE TISSUE PROTEINS; NEUROENDOCRINE SECRETORY PROTEIN 7B2; PITUITARY HORMONES; PROPROTEIN CONVERTASE 2; PROTEIN BINDING; PROTEIN PRECURSORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; SUBTILISINS;

EID: 0034640287     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.19.14667     Document Type: Article

References (58)

1. Rouille, Y., Duguay, S. J., Lund, K., Furuta, M., Gong, Q., Lipkind, G., Oliva, A. A. Jr, Chan, S. J., and Steiner, D. F. (1995) Front. Neuroendocrinol. 16, 322-361
2. Seidah, N. G., and Chretien, M. (1997) Curr, Opin. Biotechnol. 8, 602-607
3. Zhou, A., Webb, G., Zhu, X., and Steiner, D. F. (1999) J. Biol. Chem. 274, 20745-20748
4. Christie, D., Batchelor, D. C., and Palmer, D. J. (1991) J. Biol. Chem. 266, 15679-15683
5. Benjannet, S., Reudelhuber, T., Mercure, C., Rondeau, N., Chretien, M., and Seidah, N. G. (1992) J. Biol. Chem. 267, 11417-11423
6. Zhou, Y., and Lindberg, I. (1993) J. Biol. Chem. 268, 5615-5623
7. Shennan, K. I. J., Taylor, N. A., Jermany, J. L., Matthews, G., and Docherty, K. (1995) J. Biol. Chem. 270, 1402-1407
8. Matthews, G., Shennan, K. I. J., Seal, A. J., Taylor, N. A., Colman, A., and Docherty, K. (1994) J. Biol. Chem. 269, 588-592
9. Scougall, K., Taylor, N. A., Jermany, J. L., Doeherty, K., and Shennan, K. I. J. (1998) Biochem. J. 334, 531-537
10. Lamango, N. S., Apletalina E., Liu J, and Lindberg I (1999) Arch. Biochem. Biophys. 362, 275-282
11. Benjannet, S., Rondeau, N., Paquet, L., Boudreault, A., Lazure, C., Chretien, M., and Seidah, N. G. (1993) Biochem. J. 294, 735-743
12. Zhou, A., and Mains, R. E. (1994) J. Biol. Chem. 269, 17440-17447
13. Coates, L. C., and Birch, N. P. (1997) J. Neurochem. 68, 828-836
14. Boudreault, A., Gauthier, D., and Lazure, C. (1998) J. Biol. Chem. 273, 31574-31580
15. Siezen, R., and Leunissen, J. A. (1997) Protein Sci. 6, 501-523
16. Dupuy, A., Lindberg, I., Zhou, Y., Akil, H., Lazure, C., Chretien, M., Seidah, N. G., and Day, R. (1994) FEBS Lett. 337, 60-65
17. Dhanvantari, S., Seidah, N. G., and Brubaker, P. L. (1996) Mol. Endocrinol. 10, 342-355
18. Day, R., Lazure, C., Basak, A., Boudreault, A., Limperis, P., Dong, W., and Lindberg, I. (1998) J. Biol. Chem. 273, 829-836
19. Jean, F., Boudreault, A., Basak, A., Seidah, N. G., and Lazure, C. (1995) J. Biol. Chem. 270, 19225-19231
20. Johanning, K, Juliano M. A., Juliano, L., Lazure, C., Lamango, N., Steiner, D. F., and Lindberg, I. (1998) J. Biol. Chem. 273, 22672-22680
21. Lazure, C., Gauthier, D., Jean, F., Boudreault, A., Bennett, H. P. J., and Hendy, G. (1998) J. Biol. Chem. 273, 8572-8580
22. Mathis, J., and Lindberg, I. (1992) Endocrinology 131, 2287-2296
23. Johanning, K., Mathis, J. P., and Lindberg, I. (1996) J. Neurochem. 66, 898-907
24. Benjannet, S., Rondeau. N., Day, R., Chretien, M., and Seidah, N. G. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 3564-3568
25. Zhou, A., Bloomquist, B. T., and Mains, R. E. (1993) J. Biol. Chem. 268, 1763-1769
26. Rouille, Y., Martin, S., and Steiner, D. F. (1995) J. Biol. Chem. 270, 26488-26496
27. Rouille, Y., Kantengwa, S., Irminger, J. C., and Halban, P. A. (1997) J. Biol. Chem. 272, 32810-32816
28. Yoon, J., and Beinfeld, M. C. (1997) Endocrinology 138, 3620-3623
29. Rovere, C., Barbero, P., and Kitabgi, P. (1996) J. Biol. Chem. 271, 11368-75
30. Viale, A., Ortola, C., Hervieu, G., Furuta, M., Barbero, P., Steiner, D. F., Seidah, N. G., and Nahon, J.-L. (1999) J. Biol. Chem. 274, 6536-6545
31. Lipkind, G., Gong, Q., and Steiner, D. F. (1995) J. Biol. Chem. 270, 13277-13284
32. Zhu, X., and Lindberg, I. (1995) J. Cell Biol. 129, 1641-1650
33. Benjannet, S., Savaria, D., Chretien, M., and Seidah, N. G. (1995) J. Neurochem. 64, 2303-2311
34. Muller L., Zhu X., and Lindberg I. (1997) J. Cell Biol. 139, 625-638
35. Seidel, B., Dong, W., Savaria, D., Zheng, M., Pintar, J. E., and Day, R. (1998) DNA Cell Biol. 17, 1017-1029
36. Barbero, P., and Kitabgi, P. (1999) Biochem. Biophys. Res. Commun. 267, 473-479
37. Westphal, C. H., Muller, L., Zhou, A., Bonner-Weir, S., Schambelan, M., Steiner, D. F., Lindberg, I., and Leder, P. (1999) Cell 96, 689-700
38. Ayoubi, T. A. Y., van Duijnhoven, H. L. P., van de Ven, W. J. M., Jenks, B. G., Roubos, E. W., and Martens, G. J. M. (1990) J. Biol. Chem. 265, 15644-15647
39. Paquet, L., Bergeron, F., Boudreault, A., Seidah, N. G., Chretien, M., Mbikay, M., and Lazure, C. (1994) J. Biol. Chem. 269, 19279-19285
40. Lindberg, I., Van den Hurk, W. H., Bui, C., and Batie, C. J. (1995) Biochemistry 34, 5486-5493
41. Van Horssen, A. M., Van den Hurk, W. H., Bailyes, E. M., Hutton, J. C., Martens, G. J. M., and Lindberg, I. (1995) J. Biol. Chem. 270, 14292-14296
42. Zhu, X., Rouille, Y., Lamango, N. S., Steiner, D. F., and Lindberg, I. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 4919-4924
43. Fortenberry, Y., Liu, J., and Lindberg, I. (1999) J. Neurochem. 73, 994-1003
44. Apletalina, E. V., Juliano, M. A., Juliano, L., Lindberg, I. (2000) Biochem. Biophys. Res. Commun. 267, 940-942
45. Martens, G. J. M., Braks, J. A. M., Eib, D. W., Zhou, Y., and Lindberg, I. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 5784-5785
46. Muller, L., Zhu, P., Juliano, M. A., Juliano, L., and Lindberg, I. (1999) J Biol. Chem. 274, 21471-21477
47. Zhu, X., Muller, L., Mains, R. E.. and Lindberg, I. (1998) J. Biol. Chem. 273, 1158-1164
48. Benjannet, S., Lusson, J., Savaria, D., Chretien, M., and Seidah, N. G. (1995) FEBS Lett. 362, 151-155
49. Benjannet, S., Mamarbachi, A. M., Hamelin, J., Savaria, D., Munzer, J. S., Chretien, M., and Seidah, N. S. (1998) FEBS Lett. 428, 37-42
50. Siezen, R. J., Creemers, J. W. M., and Van de Ven, W. J. M. (1994) Eur. J. Biochem. 222, 255-266
51. Apletalina, E., Appel, J., Lamango, N. S., Houghten, R. A., and Lindberg, I. (1998) J. Biol. Chem. 273, 26589-26595
52. Lindberg, I., and Zhou, Y. (1995) in Peptidases and Neuropeptide Processing (Smith, A. I., ed) pp. 94-108, Academic Press, Inc., San Diego
53. Shen, F-S, Seidah, N. G. and Lindberg, I. (1993) J. Biol. Chem. 268, 24910-24915
54. Mains, R. E., Dickerson, I. M., May, V., Stoffers, D. A., Perkins, S. N., Ouafik, L., Husten, E. J., and Eipper, B. (1990) Front. Neuroendocrinol. 11, 52-89
55. Lindberg, I., and White, L. (1986) Biochem. Biophys. Res. Commun. 139, 1024-1032
56. Lamango, N. S., Zhu, X., and Lindberg, I. (1996) Arch. Biochem. Biophys. 330, 238-250
57. Yoon, J., and Beinfeld, M. C. (1997) J. Biol. Chem. 272, 9450-9456
58. Braks, J. A. M., and Martens, G. J. M. (1994) Cell 78, 263-273