Residues unique to the pro-hormone convertase PC2 modulate its autoactivation, binding to 7B2 and enzymatic activity

FEBS Letters

Volumn 428, Issue 1-2, 1998, Pages 37-42

  Benjannet, Suzanne ^a   Mamarbachi, Aida M ^a   Hamelin, Josée ^a   Savaria, Diane ^a   Munzer, Jon Scott ^a   Chrétien, Michel ^a   Seidah, Nabil G ^a  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

7B2; Convertase; Pair of basic residues; Precursor convertase 2; Processing; Prohormone; Proopiomelanocortin

Indexed keywords

BETA ENDORPHIN; BINDING PROTEIN; FURIN; FURIN BINDING PROTEIN 7 B 2; PROOPIOMELANOCORTIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ENZYME ACTIVATION; ENZYME BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; SITE DIRECTED MUTAGENESIS;

ANIMALS; ASPARTIC ACID; CELL LINE; CERCOPITHECUS AETHIOPS; ENZYME ACTIVATION; ENZYME PRECURSORS; HOMEOSTASIS; MUTAGENESIS, SITE-DIRECTED; NERVE TISSUE PROTEINS; NEUROENDOCRINE SECRETORY PROTEIN 7B2; PITUITARY HORMONES; PROPROTEIN CONVERTASE 2; SUBTILISINS; TYROSINE;

ANIMALIA; MAMMALIA;

EID: 0032557531     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(98)00480-3     Document Type: Article

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