Selective inhibition of the prothrombinase complex: Factor Va alters macromolecular recognition of a tick anticoagulant peptide mutant by factor Xa

Biochemistry

Volumn 36, Issue 1, 1997, Pages 181-191

  Betz, Andreas ^a   Vlasuk, George P ^b   Bergum, Peter W ^b   Krishnaswamy, Sriram ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Dendreon   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT PROTEIN; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 5A;

AMINO ACID SUBSTITUTION; ARTICLE; BLOOD CLOTTING; CONFORMATIONAL TRANSITION; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME INHIBITION; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

ANIMALS; BENZAMIDINES; BINDING SITES; CATTLE; FACTOR V; FACTOR VA; FACTOR X; FACTOR XA; KINETICS; MODELS, CHEMICAL; MUTAGENESIS, SITE-DIRECTED; PEPTIDES; PHOSPHATIDYLCHOLINES; PROTEIN BINDING; PROTEIN CONFORMATION; SERINE PROTEINASE INHIBITORS; SPECTROMETRY, FLUORESCENCE;

EID: 0031030267     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi962060g     Document Type: Article

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