SCOPUS 정보 검색 플랫폼

Journal of Molecular Structure: THEOCHEM

Volumn 529, Issue 1-3, 2000, Pages 273-282

QSAR development to describe HIV-1 integrase inhibition

Author keywords

Human immunodeficiency virus; Inhibition; Integrase; Multiple linear regression; Quantitative structure activity relationship

Indexed keywords

HYDRAZINE DERIVATIVE; INTEGRASE; INTEGRASE INHIBITOR; SALICYHYDRAZINE; TYRPHOSTIN; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS ENZYME;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANTIVIRAL ACTIVITY; ARTICLE; DRUG BINDING; DRUG MECHANISM; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN IMMUNODEFICIENCY VIRUS 1; IC 50; MOLECULAR MODEL; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; VIRUS REPLICATION;

EID: 0034623205 PISSN: 01661280 EISSN: None Source Type: Journal
DOI: 10.1016/S0166-1280(00)00553-4 Document Type: Article

Times cited : (20)

References (18)

1
- 0028971801
- Progress in anti-HIV structure-based drug design
- (1995) Trends Biotech. , vol.13 , pp. 430-438
- Gait, M.J.¹ Karn, J.²

2
- 13144275199
- HIV Integrase: The next target?
- (1998) Infect. Med. , vol.15 , pp. 129-137
- Robinson, W.E.J.¹

3
- 0029814410
- Retroviral integrase, putting the pieces together
- (1996) J. Biol. Chem. , vol.271 , pp. 3-19636
- Andrake, M.D.¹ Skalka, A.M.²

4
- 34250082672
- Review of HIV-1 reverse transcriptase three-dimensional structure: Implications for drug design
- (1993) Perspect. Drug Disc. Des. , vol.1 , pp. 129-150
- Nanni, R.G.¹ Ding, J.² Jacobo-Molina, A.³ Hughes, S.H.⁴ Arnold, E.⁵

5
- 0029011730
- Toward improved anti-HIV chemotheray: Therapeutic strategies for intervention with HIV infections
- (1995) J. Med. Chem. , vol.38 , pp. 2491-2517
- De Clercq, E.¹

6
- 0242677271
- A Quantitative approach to biochemical structure-activity relationships
- (1969) Acc. Chem. Res. , vol.2 , pp. 232-239
- Hansch, C.¹

7
- 0008048345
- MOE, Chemical Computing Group, Montreal
- (1998)

8
- 0008124742
- Cerius2, Molecular Simulations, Inc.
- (1999)

9
- 14444276046
- Salicylhydrazine-containing inhibitors of HIV-1 integrase: Implication for a selective chelation in the integrase active site
- (1998) J. Med. Chem. , vol.41 , pp. 3202-3209
- Neamati, N.¹ Hong, H.² Owen, J.M.³ Sunder, S.⁴ Winslow, H.E.⁵ Christensen, J.L.⁶ Zhao, H.⁷ Burke, T.R.J.⁸ Milne, G.W.A.⁹ Pommier, Y.¹⁰

10
- 0028820595
- Effects of tyrphostins, protein kinase inhibitors, on human immunodeficiency virus type 1 integrase
- (1995) Biochemistry , vol.34 , pp. 15111-15122
- Mazumder, A.¹ Gazit, A.² Levitzki, A.³ Nicklaus, M.⁴ Yung, J.⁵ Kohlhagen, G.⁶ Pommier, Y.⁷

11
- 0037571112
- Merck molecular force field. I. Basis, form, scope, parameterization, and performance of MMFF94(*)
- (1996) J. Comput. Chem. , vol.17 , pp. 490-519
- Halgren, T.A.¹

12
- 0027692921
- Traditional topological indices vs electronic geometrical and combined molecular descriptors in QSAR/QSPR research
- (1993) J. Chem. Inform. Comput. Sci. , vol.33 , pp. 835-857
- Katritzky, A.R.¹ Gordeeva, E.V.²

13
- 0000805679
- The molecular connectivity chi indexes and kappa shape indexes in structure-property modeling
- D.B. Boyd, K. Lipkowitz (Eds.), Reviews in Computational Chemistry, vol. 2, VCH, New York
- (1991) , pp. 367-422
- Hall, L.H.¹ Kier, L.B.²

14
- 0031875905
- Styrylquinoline derivatives: A new class of potent HIV-1 integrase inhibitors that block HIV-1 replication in CEM cells
- (1998) J. Med. Chem. , vol.41 , pp. 2846-2857
- Mekouar, K.¹ Mouscadet, J.-F.² Desmaele, D.³ Subra, F.⁴ Leh, H.⁵ Savoure, D.⁶ Auclair, C.⁷ D'Angelo, J.⁸

15
- 0030936836
- Arylamide inhibitors of HIV-1 integrase
- (1997) J. Med. Chem. , vol.40 , pp. 1186-1194
- Zhao, H.¹ Neamati, N.² Mazumder, A.³ Sunder, S.⁴ Pommier, Y.⁵ Burke, T.R.J.⁶

16
- 0342569810
- Structure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitor
- (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 4831-4836
- Lubkowski, J.¹ Yang, F.² Alexandratos, J.³ Wlodawer, A.⁴ Zhao, H.⁵ Burke, T.R.J.⁶ Neamati, N.⁷ Pommier, Y.⁸ Merkel, G.⁹ Skalka, A.M.¹⁰

17
- 13044295993
- Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: A platform for antiviral drag discovery
- (1999) Proc. Natl. Acad. Sci., USA , vol.96 , pp. 13040-13043
- Goldgur, Y.¹ Craigie, R.² Cohen, G.H.³ Fujiwara, T.⁴ Fujishita, T.⁵ Sugimoto, H.⁶ Endo, T.⁷ Murai, H.⁸ Davies, D.R.⁹

18
- 0008048350
- HIV integrase inhibitor interactions with active site metal ions: Fact or fiction
- T. Cundari (Ed.), Computational Organometallic Chemistry, Dekker, New York, chapter 7
- (2000)
- Parrill, A.L.¹ Ray, G.B.² Abu-Khudeir, M.³ Hirsh, A.⁴ Jolly, A.⁵

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.