Analysis of mutations and suppressors affecting interactions between the subunits of the HIV type 1 reverse transcriptase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 12, 2000, Pages 6334-6339

  Tachedjian, Gilda ^a   Aronson, Hans Erik G ^a   Goff, Stephen P ^a  

^a College of Physicians and Surgeons ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; COMPLEMENTARY DNA; RNA; RNA DIRECTED DNA POLYMERASE; TRYPTOPHAN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; DIMERIZATION; ENZYME ACTIVITY; HUMAN IMMUNODEFICIENCY VIRUS 1; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

DIMERIZATION; HIV-1 REVERSE TRANSCRIPTASE; MUTAGENESIS, SITE-DIRECTED; RECOMBINANT FUSION PROTEINS;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0034612275     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.12.6334     Document Type: Article

References (40)

1. di Marzo Veronese, F., Copeland, T. D., DeVico, A. L., Rahman, R., Oroszlan, S., Gallo, R. C. & Sarngadharan, M. G. (1986) Science 231, 1289-1291.
2. Rodgers, D. W., Gamblin, S. J., Harris, B. A., Ray, S., Culp, J. S., Hellmig, B., Woolf, D. J., Debouck, C. & Harrison, S. C. (1995) Proc. Natl. Acad. Sci. USA 92, 1222-1226.
3. Ren, J., Esnouf, R., Garman, E., Somers, D., Ross, C., Kirby, I., Keeling, J., Darby, G., Jones, Y., Stuart, D., et al. (1995) Nat. Struct. Biol 2, 293-302.
4. Huang, H., Chopra, R., Verdine, G. L. & Harrison, S. C. (1998) Science 282, 1669-1675.
5. Jacobo-Molina, A., Ding, J., Nanni, R. G., Clark, A. D., Jr., Lu, X., Tantillo, C., Williams, R. L., Kamer, G., Ferris, A. L., Clark, P., et al. (1993) Proc. Natl. Acad. Sci. USA 90, 6320-6324.
6. Kohlstaedt, L. A., Wang, J., Friedman, J. M., Rice, P. A. & Steitz, T. A. (1992) Science 256, 1783-1790.
7. Restle, T., Muller, B. & Goody, R. S. (1990) J. Biol. Chem. 265, 8986-8988.
8. Becerra, S. P., Kumar, A., Lewis, M. S., Widen, S. G., Abbotts, J., Karawya, E. M., Hughes, S. H., Shiloach, J. & Wilson, S. H. (1991) Biochemistry 30, 11707-11719.
9. Wang, J., Smerdon, S. J., Jager, J., Kohlstaedt, L. A., Rice, P. A., Friedman, J. M. & Steitz, T. A. (1994) Proc. Natl. Acad. Sci. USA 91, 7242-7246.
10. Ghosh, M., Jacques, P. S., Rodgers, D. W., Ottman, M., Darlix, J. L. & Le Grice, S. F. (1996) Biochemistry 35, 8553-8562.
11. Wohrl, B. M., Krebs, R., Thrall, S. H., Le Grice, S. F. J., Scheidig, A. J. & Goody, R. S. (1997) J. Biol. Chem. 272, 17581-17587.
12. Goel, R., Beard, W. A., Kumar, A., Casas-Finet, J. R., Strub, M. P., Stahl, S. J., Lewis, M. S., Bebenek, K., Becerra, S. P., Kunkel, T. A., et al. (1993) Biochemistry 32, 13012-13018.
13. Divita, G., Restle, T. & Goody, R. S. (1993) FEBS Lett. 324, 153-158.
14. Debyser, Z. & De Clercq, E. (1996) Protein Sci. 5, 278-286.
15. Jacques, P. S., Wohrl, B. M., Howard, K. J. & Le Grice, S. F. (1994) J. Biol. Chem. 269, 1388-1393.
16. Fields, S. & Song, O. (1989) Nature (London) 340, 245-246.
17. Kalpana, G. V. & Goff, S. P. (1993) Proc. Natl. Acad. Sci. USA 90, 10593-10597.
18. Luban, J., Bossolt, K. L., Franke, E. K., Kalpana, G. V. & Goff, S. P. (1993) Cell 73, 1067-1078.
19. Rose, M. D., Winston, F. & Hieter, P. (1990) Methods in Yeast Genetics: A Laboratory Course Manual. (Cold Spring Harbor Lab. Press, Plainview, NY).
20. Szilvay, A. M., Nornes, S., Haugan, I. R., Olsen, L., Prasad, V. R., Endresen, C., Goff, S. P. & Helland, D. E. (1992) J. Acquired Immune Defic. Syndr. 5, 647-657.
21. Telesnitsky, A., Blain, S. & Goff, S. P. (1995) Methods Enzymol. 262, 347-362.
22. Hanes, S. D. & Brent, R. (1989) Cell 57, 1275-1283.
23. Ruden, D. M., Ma, J., Li, Y., Wood, K. & Ptashne, M. (1991) Nature (London) 350, 250-252.
24. Legrain, F., Dokhelar, M. C. & Transy, C. (1994) Nucleic Acids Res. 22, 3241-3242.
25. Maldarelli, F., Martin, M. A. & Strebel, K. (1991) J. Virol. 65, 5732-5743.
26. Ratner, L., Haseltine, W., Patarca, R., Livak, K. J., Starcich, B., Josephs, S. F., Doran, E. R., Rafalski, J. A., Whitehorn, E. A., Baumeister, K., et al. (1985) Nature (London) 313, 277-284.
27. Maier, G., Dietrich, U., Panhans, B., Schroder, B., Rubsamen-Waigmann, H., Cellai, L., Hermann, T. & Heumann, H. (1999) Eur. J. Biochem. 261, 10-18.
28. Larder, B. A., Purifoy, D. J., Powell, K. L. & Darby, G. (1987) Nature (London) 327, 716-717.
29. Baillon, J. G., Nashed, N. T., Kumar, A., Wilson, S. H. & Jerina, D. M. (1991) New Biol. 3, 1015-1019.
30. Harris, D., Lee, R., Misra, H. S., Pandey, P. K. & Pandey, V. N. (1998) Biochemistry 37, 5903-5908.
31. Sluis-Cremer, N., Dmitrienko, G. I., Balzarini, J., Camarasa, M. J. & Parniak, M. A. (2000) Biochemistry 39, 1427-1433.
32. Divita, G., Restle, T., Goody, R. S., Chermann, J. C. & Baillon, J. G. (1994) J. Biol. Chem. 269, 13080-13083.
33. Georgiadis, M. M., Jessen, S. M., Ogata, C. M., Telesnitsky, A., Goff, S. P. & Hendrickson, W. A. (1995) Structure (London) 3, 879-892.
34. Esnouf, R., Ren, J., Ross, C., Jones, Y., Stammers, D. & Stuart, D. (1995) Nat. Struct. Biol. 2, 303-308.
35. Spence, R. A., Kati, W. M., Anderson, K. S. & Johnson, K. A. (1995) Science 267, 988-993.
36. Patel, P. H., Jacobo-Molina, A., Ding, J., Tantillo, C., Clark, A. D., Jr., Raag, R., Nanni, R. G., Hughes, S. H. & Arnold, E. (1995) Biochemistry 34, 5351-5363.
37. Morris, M. C., Robert-Hebmann, V., Chaloin, L., Mery, J., Heitz, F., Devaux, C., Goody, R. S. & Divita, G. (1999) J. Biol. Chem. 274, 24941-24946.
38. Kraulis, P. J. (1991) J. Appl. Crystallogr. 24, 946-950.
39. Merrit, E. A. & Bacon, D. J. (1997) Methods Enzymol. 277, 505-524.
40. Kabsch, W. & Sander, C. (1983) Biopolymers 22, 2577-2637.