Anticoagulant effects of retinoic acids on leukemia cells

Blood

Volumn 87, Issue 2, 1996, Pages 657-665

  Saito, Takako ^b   Koyama, Takatoshi ^a   Nagata, Kaoru ^b   Kamiyama, Ryuichi ^b   Hirosawa, Shinsaku ^b  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALITRETINOIN; ISOTRETINOIN; RETINOIC ACID; RETINOIC ACID DERIVATIVE; RETINOIC ACID RECEPTOR; RETINOID X RECEPTOR; THROMBIN; THROMBOMODULIN; THROMBOPLASTIN;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE MONOCYTIC LEUKEMIA; ACUTE MYELOBLASTIC LEUKEMIA; ANTIGEN EXPRESSION; ARTICLE; BLOOD CLOTTING; CANCER CELL CULTURE; CELL DIFFERENTIATION; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; DISSEMINATED INTRAVASCULAR CLOTTING; DRUG MECHANISM; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

EID: 0030031678     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v87.2.657.bloodjournal872657     Document Type: Article

References (21)

1. Koyama T, Hirosawa S, Kawamata N, Tohda S, Aoki N: All-trans retinoic acid (ATRA) upregulates thrombomodulin and down-regulates tissue factor expression in acute promyelocytic leukemia cells: Distinct expression of thrombomodulin and tissue factor in human leukemic cells Blood 84:3001, 1994
2. Heyman RA, Mangelsdorf DJ, Dyck JA, Stein RB, Eichele G, Evans RM, Thaller C: 9-cis retinoic acid is a high affinity ligand for the retinoid X receptor. Cell 68:397, 1992
3. Kizaki M, Ikeda Y, Tanosaki R, Nakajima H, Monkawa M, Sakashita A, Koeffler HP: Effects of novel retinoic acid compound, 9-cis-retinoic acid, on proliferation, differentiation, and expression of retinoic acid receptor-α and retinoid X receptor-α RNA by HL-60 cells. Blood 82:3592, 1993
4. Miller WH Jr, Jakubowski A, Tong WP, Miller VA, Rigas JR, Benedetti F, Gill GM, Truglia JA, Ulm E, Shirley M, Warrell RP Jr: 9-cis retinoic acid induces complete remission but does not reverse clinically acquired retinoid resistance in acute promyelocytic leukemia. Blood 85:3021, 1995
5. Kimura S, Nagoya T, Aoki N: Monoclonal antibodies to human thrombomodulin whose binding is calcium dependent. J Biochem 105:478, 1989
6. Koyama T, Parkinson JF, Aoki N, Bang NU, Müller-Berghaus G, Preissner KT: Relationship between post-translational glycosylation and anticoagulant function of secretable, recombinant mutants of human thrombomodulin. Br J Haematol 78:515, 1991
7. Lanotte M, Martin-Thouvenin V, Najiman S, Balerini P, Valensi F, Berger R: NB4, a maturation inducible cell line with t(15:17) marker isolated from a human acute promyelocytic leukemia (M3). Blood 77:1080, 1991
8. Dermime S, Grignani F, Clerici M, Nervi C, Sozzi G, Talamo GP, Marchesi E, Formelli F, Parmiani G, Pelicci PG, Gambacorti-Passerini C: Occurrence of resistance to retinoic acid in the acute promyelocytic leukemia cell line NB4 is associated with altered expression of the pml/RARα protein. Blood 82:1573, 1993
9. Yamamoto K, Hirosawa S, Sakamaki H, Aoki N: Frequent rearrangements of retinoic acid receptor alpha gene and Myl gene, and rare mutations of RAS and FMS genes in acute promyelocytic leukemia. Am J Hematol 40:252, 1992
10. Ohashi K, Hirokawa K, Komatsu N, Aoki N: The biosynthesis of thrombomodulin and its enhancement by dibutyryl cAMP in a human megakaryoblastic cell line, UT-7. Int J Hematol 54:341, 1991
11. Koyama T, Nishida K, Ohdama S, Sawada M, Murakami N, Hirosawa S, Kuriyama R, Matsuzawa K, Hasegawa R, Aoki N: Determination of plasma tissue factor antigen and its clinical significance. Br J Haematol 87:343, 1994
12. Wakita K, Marumoto Y, Horiuchi T: Up-regulation of tissue factor mRNA in human umbilical vein endothelial cells by calmodulin inhibitor W7. Thromb Res 73:177, 1994
13. Falanga A, Consonni R, Marchetti M, Mielicki WP, Rambaldi A, Lanotte M, Gordon SG, Barbui T: Cancer procoagulant in the human promyelocytic cell line NB4 and its modulation by all-trans retinoic acid. Leukemia 8:156, 1994
14. Kawai Y, Watanabe K, Kizaki M, Murata M, Kamata T, Uchida H, Moriki T, Yokoyama K, Tokuhira M, Nakajima H, Handa M, Ikeda Y: Rapid improvement of coagulopathy by all-trans retinoic acid in acute promyelocytic leukemia. Am J Hematol 46, 184, 1994
15. Tapiovaara H, Matikainen S, Hurme M, Vaheri A: Induction of differentiation of promyelocytic NB4 cells by retinoic acid is associated with rapid increase in urokinase activity subsequently downregulated by production of inhibitors. Blood 83:1883, 1994
16. Dombret H, Scrobohaci M-L. Daniel M-T, Micléa J-M, Castaigne S, Chomienne C, Fenaux P, Degos L: In vivo thrombin and plasmin activities in patients with acute promyelocytic leukemia (APL): Effect of all trans retinoic acid (ATRA) therapy. Leukemia 9:19, 1995
17. De Munk G, Groeneveld E, Rijken D. Acceleration of the thrombin inactivation of single-chain urokinase-type plasminogen activator (pro-urokinase) by thrombomodulin. J Clin Invest 88:1680, 1991
18. Molinari A, Giorgetti C, Lausen J, Vaghi F, Orsini G, Faioni EM, Mannucci PM: Thrombomodulin is a cofactor for thrombin degradation of recombinant single-chain urokinase plasminogen activator "in vitro" and in a perfused rabbit heart model. Thromb Haemost 67:226, 1992
19. Bennett B, Booth NA, Croll A, Duncan A, Dawson AA. The bleeding disorder in acute promyelocytic leukaemia: Fibrinolysis due to u-PA rather than defibrination. Br J Haematol 71:511, 1989
20. Kizaki K, Ishii H, Horie S, Kazama M: Thrombomodulin induction by all-trans retinoic acid is independent of HL-60 cells differentiation to neutrophilic cells Thromb Haemost 72:573, 1994
21. Falanga A, Consonni R, Oldani E, Marchetti M, Gambacorti-Passerini C, Lanotte M, Barbui T: Effect of all-trans-retinoic acid on the procoagulant activity of retinoic acid-"resistant" human promyelocytic cell lines. Thromb Haemost 73:1280, 1995 (abstr)