Enhanced productivity during controlled proliferation of BHK cells in continuously perfused bioreactors

Biotechnology and Bioengineering

Volumn 69, Issue 3, 2000, Pages 266-274

  Geserick, Christoph ^a,b   Bonarius, Hendrik P J ^b   Kongerslev, Leif ^b   Hauser, Hansjörg ^a   Mueller, Peter P ^a  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^b NOVO NORDISK A S   (Denmark)

Author keywords

Baby hamster kidney (BHK) cells; Dicistronic mRNA; IRF 1; Microcarrier; Proliferation control; Recombinant IgG anti body production

Indexed keywords

ANTIBODIES; BIOREACTORS; CELLS; GROWTH KINETICS; PROTEINS; RNA;

BABY HAMSTER KIDNEY CELLS; CONTINOUSLY PERFUSED BIOREACTORS; MICROCARRIER; PROLIFERATION CONTROL;

CELL CULTURE;

IMMUNOGLOBULIN G ANTIBODY; INTERFERON REGULATORY FACTOR 1; RECOMBINANT ANTIBODY;

ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; BIOREACTOR; CELL CULTURE; CELL DENSITY; CELL PROLIFERATION; CELL STRAIN BHK; CONTROLLED STUDY; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS;

ANIMALS; BIOREACTORS; CELL COUNT; CELL DIVISION; CELL LINE; CELL SURVIVAL; CLONE CELLS; CRICETINAE; CULTURE TECHNIQUES; DIMERIZATION; DNA-BINDING PROTEINS; ESTROGENS; GENES, VIRAL; IMMUNOGLOBULIN G; INTERFERON REGULATORY FACTOR-1; MICROSPHERES; PERFUSION; PHOSPHOPROTEINS; PROMOTER REGIONS (GENETICS); RECEPTORS, ESTROGEN; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; TIME FACTORS; TRANS-ACTIVATION (GENETICS);

ANIMALIA; CRICETINAE;

EID: 0034609237     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0290(20000805)69:3<266::AID-BIT4>3.0.CO;2-Z     Document Type: Article

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