Shiga toxin 1: Damage to DNA in vitro

Toxicon

Volumn 39, Issue 2-3, 2001, Pages 341-348

  Brigotti, Maurizio ^a   Accorsi, Paola ^a   Carnicelli, Domenica ^a   Rizzi, Simona ^a   González Vara, Antonio ^b   Montanaro, Lucio ^a   Sperti, Simonetta ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b Dipto Chim Applicata Sci Dei M   (Italy)

Author keywords

DNA; DNA glycosylase; DNA glycosylase AP lyase; Gelonin; Ribosome inactivity proteins; Shiga toxin 1

Indexed keywords

ADENINE; DITHIOTHREITOL; DNA; DNA BASE; DNA GLYCOSYLTRANSFERASE; LYASE; RIBOSOME INACTIVATING PROTEIN; RNA; SHIGA TOXIN; SINGLE STRANDED DNA; SODIUM CHLORIDE; TRITIUM; TRYPSIN; UNCLASSIFIED DRUG; URACIL; UREA; VEROTOXIN 1;

CONFERENCE PAPER; CONTROLLED STUDY; DNA DAMAGE; ENZYME SUBSTRATE COMPLEX; PH; PRIORITY JOURNAL; PROTEIN DEGRADATION; RIBOSOME;

EID: 0034598651     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(00)00135-5     Document Type: Conference Paper

References (27)

1. Barbieri L., Battelli M.G., Stirpe F. Ribosome-inactivating proteins from plants. Biochim. Biophys. Acta. 1154:1993;237-282.
2. Barbieri L., Gorini P., Valbonesi P., Castiglioni P., Stirpe F. Unexpected activity of saporins. Nature. 372:1994;624.
3. Barbieri L., Valbonesi P., Bonora E., Gorini P., Bolognesi A., Stirpe F. Polynucleotide:adenosine glycosidase activity of ribosome-inactivating proteins: effect on DNA, RNA and poly(A). Nucleic Acids Res. 25:1997;518-522.
4. Barbieri L., Valbonesi P., Brigotti M., Montanaro L., Stirpe F., Sperti S. Shiga-like toxin I is a polynucleotide:adenosine glycosidase. Mol. Microbiol. 29:1998;661-662.
5. Brigotti M., Carnicelli D., Alvergna P., Mazzaracchio R., Sperti S., Montanaro L. The RNA-N-glycosidase activity of Shiga-like toxin I: kinetic parameters of the native and activated toxin. Toxicon. 35:1997;1431-1437.
6. Brigotti M., Barbieri L., Valbonesi P., Stirpe F., Montanaro L., Sperti S. A rapid and sensitive method to measure the enzymatic activity of ribosome-inactivating proteins. Nucleic Acids Res. 26:1998;4306-4307.
7. Day P.J., Lord J.M., Roberts L.M. The deoxyribonuclease activity attributed to ribosome-inactivating proteins is due to a contamination. Eur. J. Biochem. 258:1998;540-545.
8. Dodson M.L., Michaels M.L, Lloyd R.S. Unified catalytic mechanism for DNA glycosylases. J. Biol. Chem. 269:1994;32709-32712.
9. Donohue-Rolfe A., Jacewicz M., Keusch G.T. Shiga toxin as inhibitor of protein synthesis. Methods Enzymol. 165:1988;231-235.
10. Endo Y., Tsurugi K., Yutsudo T., Takeda Y., Ogasawara T., Igarashi K. Site of action a Vero toxin (VT2) from E. coli O157:H7 and of Shiga toxin on eukaryotic ribosomes. RNA N-glycosidase activity of the toxins. Eur. J. Biochem. 171:1988;45-50.
11. Garred O., van Deurs B., Sandvig K. Furin-induced cleavage and activation of Shiga toxin. J. Biol. Chem. 270:1995;10817-10821.
12. Girard P.-M., Guibourt N., Boiteux S. The Ogg1 protein of Saccharomyces cerevisiae: a 7,8-dihydro-8-oxoguanine DNA glycosylase/AP lyase whose lysine 241 is a critical residue for catalytic activity. Nucleic Acids Res. 25:1997;3204-3211.
13. Gruskin E.A., Lloyd R.S. The DNA scanning mechanism of T4 endonuclease V: effect of NaCl concentration on processive nicking activity. J. Biol. Chem. 261:1986;9607-9613.
14. Lindahl T. An N-glycosidase from Escherichia coli that releases free uracil from DNA containing deaminated cytosine residues. Proc. Natl. Acad. Sci. (USA). 71:1974;3649-3653.
15. Lindahl T., Ljungquist S., Siegert W., Nyberg B., Sperens B. DNA N-glycosidases: properties of uracil-DNA glycosidase: from Escherichia coli. J. Biol. Chem. 252:1977;3286-3294.
16. Nicolas E., Beggs J.M., Haltiwanger B.M., Taraschi T.F. Direct evidence for the deoxyribonuclease activity of the plant ribosome inactivating protein gelonin. FEBS Lett. 406:1997;162-164.
17. Nicolas E., Beggs J.M., Haltiwanger B.M., Taraschi T.F. A new class of DNA glycosylase/apurinic/apyrimidinic lyases that act on specific adenines in single-stranded DNA. J. Biol. Chem. 273:1998;17216-17220.
18. Pallanca A., Mazzaracchio R., Brigotti M., Carnicelli D., Alvergna P., Sperti S., Montanaro L. Uncompetitive inhibition by adenine of the RNA-N-glycosidase activity of ribosome-inactivating proteins. Biochim. Biophys. Acta. 1384:1998;277-284.
19. Paton J.C., Paton A.W. Pathogenesis and diagnosis of Shiga toxin-producing Escherichia coli infections. Clin. Microbiol. Rev. 11:1998;450-479.
20. Reisbig R., Olsnes S., Eiklid K. The cytotoxic activity of Shigella toxin: evidence for catalytic inactivation of the 60 S ribosomal subunit. J. Biol. Chem. 256:1981;8739-8744.
21. Roncuzzi L., Gasperi-Campani A. DNA-nuclease activity of the single-chain ribosome-inactivating proteins dianthin 30, saporin 6 and gelonin. FEBS Lett. 392:1996;16-20.
22. Ryd M., Alfredsson H., Blomberg L., Andersson A., Lindberg A.A. Purification of Shiga toxin by α-D-galactose-(1 → 4)-β-D-galactose-(1 → 4)-β-D-glucose-(1 →) receptor ligand-based chromatography. FEBS Lett. 258:1989;320-322.
23. Sandvig K., Garred O., Prydz K., Kozlov J.V., Hansen S.H., van Deurs B. Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum. Nature. 358:1992;510-512.
24. 1 subunit, using competition and site-directed mutagenesis. J. Bacteriol. 179:1997;1368-1374.
25. Sun B., Latham K.A., Dodson M.L., Lloyd R.S. Studies on the catalytic mechanism of five DNA glycosylases: probing for enzyme-DNA imino intermediates. J. Biol. Chem. 270:1995;19501-19508.
26. Watanabe K., Honjo E., Tsukamoto T., Funatsu G. Fluorescence studies on the interaction of adenine with ricin A-chain. FEBS Lett. 304:1992;249-251.
27. Zamboni M., Brigotti M., Rambelli F., Montanaro L., Sperti S. High-pressure-liquid-chromatographic and fluorimetric methods for the determination of adenine released from ribosomes by ricin and gelonin. Biochem. J. 259:1989;639-643.