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Volumn 274, Issue 2, 2000, Pages 415-421

Phosphodiesterases 4D and 7A splice variants in the response of HUVEC cells to TNF-α

Author keywords

Alternative splicing; cAMP phosphodiesterase; Endothelium; Gene expression; Inflammation; Tumor necrosis factor

Indexed keywords

ISOENZYME; MESSENGER RNA; PHOSPHODIESTERASE; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE VII; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 0034596252     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.3146     Document Type: Article
Times cited : (30)

References (32)
  • 1
    • 0030974622 scopus 로고    scopus 로고
    • Tailoring cAMP-signalling responses through isoform multiplicity
    • Houslay M. D., Milligan G. Tailoring cAMP-signalling responses through isoform multiplicity. Trends Biochem. 22:1997;217-224.
    • (1997) Trends Biochem. , vol.22 , pp. 217-224
    • Houslay, M.D.1    Milligan, G.2
  • 2
    • 0032605044 scopus 로고    scopus 로고
    • The molecular biology of cyclic nucleotide phosphodiesterases
    • Conti M., Jin S. L. The molecular biology of cyclic nucleotide phosphodiesterases. Prog. Nucleic Acid Res. Mol. Biol. 63:1999;1-38.
    • (1999) Prog. Nucleic Acid Res. Mol. Biol. , vol.63 , pp. 1-38
    • Conti, M.1    Jin, S.L.2
  • 4
    • 0031601339 scopus 로고    scopus 로고
    • The multienzyme PDE4 cyclic adenosine monophosphate-specific phosphodiesterase family: Intracellular targeting, regulation, and selective inhibition by compounds exerting anti-inflammatory and antidepressant actions
    • Houslay M. D., Sullivan M., Bolger G. B. The multienzyme PDE4 cyclic adenosine monophosphate-specific phosphodiesterase family: Intracellular targeting, regulation, and selective inhibition by compounds exerting anti-inflammatory and antidepressant actions. Adv. Pharmacol. 44:1998;225-342.
    • (1998) Adv. Pharmacol. , vol.44 , pp. 225-342
    • Houslay, M.D.1    Sullivan, M.2    Bolger, G.B.3
  • 11
    • 0033524977 scopus 로고    scopus 로고
    • CD3- And CD28-dependent induction of PDE7 required for T cell activation
    • Li L., Yee C., Beavo J. A. CD3- and CD28-dependent induction of PDE7 required for T cell activation. Science. 283:1999;848-851.
    • (1999) Science , vol.283 , pp. 848-851
    • Li, L.1    Yee, C.2    Beavo, J.A.3
  • 12
    • 0030587928 scopus 로고    scopus 로고
    • Transcriptional up-regulation of intracellular adhesion molecule-1 in human endothelial cells by the antioxidant pyrrolidine dithiocarbamate involves the activation of activating protein-1
    • Muñoz C., Castellanos M. C., Alfranca A., Vara A., Esteban M. A., Redondo J. M., O. de Landazuri M. Transcriptional up-regulation of intracellular adhesion molecule-1 in human endothelial cells by the antioxidant pyrrolidine dithiocarbamate involves the activation of activating protein-1. J. Immunol. 157:1996;3587-3597.
    • (1996) J. Immunol. , vol.157 , pp. 3587-3597
    • Muñoz, C.1    Castellanos, M.C.2    Alfranca, A.3    Vara, A.4    Esteban, M.A.5    Redondo, J.M.6    O. De Landazuri, M.7
  • 13
    • 0031028090 scopus 로고    scopus 로고
    • Challenge of human Jurkat T-cells with the adenylate cyclase activator forskolin elicits major changes in cAMP phosphodiesterase (PDE) expression by up-regulating PDE3 and inducing PDE4D1 and PDE4D2 splice variants as well as down-regulating a novel PDE4A splice variant
    • Erdogan S., Houslay M. D. Challenge of human Jurkat T-cells with the adenylate cyclase activator forskolin elicits major changes in cAMP phosphodiesterase (PDE) expression by up-regulating PDE3 and inducing PDE4D1 and PDE4D2 splice variants as well as down-regulating a novel PDE4A splice variant. Biochem. J. 321:1997;165-175.
    • (1997) Biochem. J. , vol.321 , pp. 165-175
    • Erdogan, S.1    Houslay, M.D.2
  • 14
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 15
    • 0028176806 scopus 로고
    • Distribution of the serotonin 5-HT2 receptor family mRNAs: Comparison between 5-HT2A and 5-HT2C receptors
    • Pompeiano M., Palacios J. M., Mengod G. Distribution of the serotonin 5-HT2 receptor family mRNAs: Comparison between 5-HT2A and 5-HT2C receptors. Mol. Brain Res. 23:1994;163-178.
    • (1994) Mol. Brain Res. , vol.23 , pp. 163-178
    • Pompeiano, M.1    Palacios, J.M.2    Mengod, G.3
  • 16
    • 0026612288 scopus 로고
    • Muscarinic M2 receptor mRNA expression and receptor binding in cholinergic and non-cholinergic cells in the rat brain: A correlative study using in situ hybridization histochemistry and receptor autoradiography
    • Vilaro M. T., Wiederhold K. H., Palacios J. M., Mengod G. Muscarinic M2 receptor mRNA expression and receptor binding in cholinergic and non-cholinergic cells in the rat brain: A correlative study using in situ hybridization histochemistry and receptor autoradiography. Neuroscience. 47:1992;367-393.
    • (1992) Neuroscience , vol.47 , pp. 367-393
    • Vilaro, M.T.1    Wiederhold, K.H.2    Palacios, J.M.3    Mengod, G.4
  • 17
    • 0027935309 scopus 로고
    • Leukocyte-endothelial adhesion molecules
    • Carlos T. M., Harlan J. M. Leukocyte-endothelial adhesion molecules. Blood. 84:1994;2068-2101.
    • (1994) Blood , vol.84 , pp. 2068-2101
    • Carlos, T.M.1    Harlan, J.M.2
  • 18
    • 0027164208 scopus 로고
    • Isolation and characterization of a previously undetected human cAMP phosphodiesterase by complementation of cAMP phosphodiesterase-deficient Saccharomyces cerevisiae
    • Michaeli T., Bloom T. J., Martins T., Loughney K., Ferguson K., Riggs M., Rodgers L., Beavo J. A., Wigler M. Isolation and characterization of a previously undetected human cAMP phosphodiesterase by complementation of cAMP phosphodiesterase-deficient Saccharomyces cerevisiae. J. Biol. Chem. 268:1993;12925-12932.
    • (1993) J. Biol. Chem. , vol.268 , pp. 12925-12932
    • Michaeli, T.1    Bloom, T.J.2    Martins, T.3    Loughney, K.4    Ferguson, K.5    Riggs, M.6    Rodgers, L.7    Beavo, J.A.8    Wigler, M.9
  • 19
    • 0032143286 scopus 로고    scopus 로고
    • Identification and characterization of the human homologue of the short PDE4A cAMP-specific phosphodiesterase RD1 (PDE4A1) by analysis of the human HSPDE4A gene locus located at chromosome 19p13.2
    • Sullivan M., Rena G., Begg F., Gordon L., Olsen A. S., Houslay M. D. Identification and characterization of the human homologue of the short PDE4A cAMP-specific phosphodiesterase RD1 (PDE4A1) by analysis of the human HSPDE4A gene locus located at chromosome 19p13.2. Biochem. J. 333:1998;693-703.
    • (1998) Biochem. J. , vol.333 , pp. 693-703
    • Sullivan, M.1    Rena, G.2    Begg, F.3    Gordon, L.4    Olsen, A.S.5    Houslay, M.D.6
  • 20
    • 0028140251 scopus 로고
    • Structure of two rat genes coding for closely related rolipram-sensitive cAMP phosphodiesterases. Multiple mRNA variants originate from alternative splicing and multiple start sites
    • Monaco L., Vicini E., Conti M. Structure of two rat genes coding for closely related rolipram-sensitive cAMP phosphodiesterases. Multiple mRNA variants originate from alternative splicing and multiple start sites. J. Biol. Chem. 269:1994;347-357.
    • (1994) J. Biol. Chem. , vol.269 , pp. 347-357
    • Monaco, L.1    Vicini, E.2    Conti, M.3
  • 21
    • 0027982876 scopus 로고
    • Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
    • Springer T. A. Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm. Cell. 76:1994;301-314.
    • (1994) Cell , vol.76 , pp. 301-314
    • Springer, T.A.1
  • 22
    • 0024601050 scopus 로고
    • Endothelial leukocyte adhesion molecule 1: An inducible receptor for neutrophils related to complement regulatory proteins and lectins
    • Bevilacqua M. P., Stengelin S., Gimbrone J. M. A., Seed B. Endothelial leukocyte adhesion molecule 1: An inducible receptor for neutrophils related to complement regulatory proteins and lectins. Science. 243:1989;1160-1165.
    • (1989) Science , vol.243 , pp. 1160-1165
    • Bevilacqua, M.P.1    Stengelin, S.2    Gimbrone, J.M.A.3    Seed, B.4
  • 23
    • 0024818401 scopus 로고
    • Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes
    • Osborn L., Hession C., Tizard R., Vassallo C., Luhowskyj S., Chi-Rosso G., Lobb R. Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes. Cell. 59:1989;1203-1211.
    • (1989) Cell , vol.59 , pp. 1203-1211
    • Osborn, L.1    Hession, C.2    Tizard, R.3    Vassallo, C.4    Luhowskyj, S.5    Chi-Rosso, G.6    Lobb, R.7
  • 24
    • 0032584673 scopus 로고    scopus 로고
    • Impaired growth and fertility of cAMP-specific phosphodiesterase PDE4D-deficient mice
    • Jin S. C., Bushnik T., Lan L., Conti M. Impaired growth and fertility of cAMP-specific phosphodiesterase PDE4D-deficient mice. J. Biol. Chem. 273:1998;19672-19678.
    • (1998) J. Biol. Chem. , vol.273 , pp. 19672-19678
    • Jin, S.C.1    Bushnik, T.2    Lan, L.3    Conti, M.4
  • 25
    • 0033591233 scopus 로고    scopus 로고
    • The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform
    • Yarwood S. J., Steele M. R., Scotland G., Houslay M. D., Bolger G. B. The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform. J. Biol. Chem. 274:1999;14909-14917.
    • (1999) J. Biol. Chem. , vol.274 , pp. 14909-14917
    • Yarwood, S.J.1    Steele, M.R.2    Scotland, G.3    Houslay, M.D.4    Bolger, G.B.5
  • 26
    • 0032882246 scopus 로고    scopus 로고
    • The unique N-terminal domain of the cAMP phosphodiesterase PDE4D4 allows for interaction with specific SH3 domains
    • Beard M. B., O'Connell J. C., Bolger G. B., Houslay M. D. The unique N-terminal domain of the cAMP phosphodiesterase PDE4D4 allows for interaction with specific SH3 domains. FEBS Lett. 460:1999;173-177.
    • (1999) FEBS Lett , vol.460 , pp. 173-177
    • Beard, M.B.1    O'Connell, J.C.2    Bolger, G.B.3    Houslay, M.D.4
  • 27
    • 0027454556 scopus 로고
    • A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs
    • Bolger G., Michaeli T., Martins T., St John T., Steiner B., Rodgers L., Riggs M., Wigler M., Ferguson K. A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs. Mol. Cell. Biol. 13:1993;6558-6571.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 6558-6571
    • Bolger, G.1    Michaeli, T.2    Martins, T.3    St John, T.4    Steiner, B.5    Rodgers, L.6    Riggs, M.7    Wigler, M.8    Ferguson, K.9
  • 28
    • 0029005315 scopus 로고
    • Molecular cloning of a novel splice variant of human type IVA (PDE-IVA) cyclic AMP phosphodiesterase and localization of the gene to the p13.2-q12 region of human chromosome 19
    • Horton Y. M., Sullivan M., Houslay M. D. Molecular cloning of a novel splice variant of human type IVA (PDE-IVA) cyclic AMP phosphodiesterase and localization of the gene to the p13.2-q12 region of human chromosome 19. Biochem. J. 308:1995;683-691.
    • (1995) Biochem. J. , vol.308 , pp. 683-691
    • Horton, Y.M.1    Sullivan, M.2    Houslay, M.D.3
  • 29
    • 0024328766 scopus 로고
    • Sex in flies: The splice of life
    • Baker B. S. Sex in flies: The splice of life. Nature. 340:1989;521-524.
    • (1989) Nature , vol.340 , pp. 521-524
    • Baker, B.S.1
  • 30
    • 0029971297 scopus 로고    scopus 로고
    • A mechanism for regulation of the adhesion-associated proteintyrosine kinase pp125FAK
    • Richardson A., Parsons J. T. A mechanism for regulation of the adhesion-associated proteintyrosine kinase pp125FAK. Nature. 380:1996;538-540.
    • (1996) Nature , vol.380 , pp. 538-540
    • Richardson, A.1    Parsons, J.T.2
  • 31
    • 0026016404 scopus 로고
    • A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity
    • Nakabeppu Y., Nathans D. A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity. Cell. 64:1991;751-759.
    • (1991) Cell , vol.64 , pp. 751-759
    • Nakabeppu, Y.1    Nathans, D.2
  • 32
    • 0028982277 scopus 로고
    • A variant of the alpha 2 subunit of soluble guanylyl cyclase contains an insert homologous to a region within adenylyl cyclases and functions as a dominant negative protein
    • Behrends S., Harteneck C., Schultz G., Koesling D. A variant of the alpha 2 subunit of soluble guanylyl cyclase contains an insert homologous to a region within adenylyl cyclases and functions as a dominant negative protein. J. Biol. Chem. 270:1995;21109-21113.
    • (1995) J. Biol. Chem. , vol.270 , pp. 21109-21113
    • Behrends, S.1    Harteneck, C.2    Schultz, G.3    Koesling, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.