Antibody-catalyzed removal of the p-nitrobenzyl ester protecting group: The molecular basis of broad substrate specificity

Chemistry - A European Journal

Volumn 6, Issue 9, 2000, Pages 1656-1662

  Kurihara, Shinwa ^a   Tsumuraya, Takeshi ^a   Suzuki, Kayo ^a   Kuroda, Masataka ^a   Liu, Lidong ^a   Takaoka, Yumiko ^a   Fujii, Ikuo ^a  

^a BIOMOL ENG RESEARCH INSTITUTE   (Japan)

Author keywords

Catalytic antibodies; Hapten; Immunization; Protecting groups; Transition states

Indexed keywords

ANTIBODY 7B9; CATALYTIC ANTIBODY; ESTER; ESTER DERIVATIVE; GLUTARIC ACID DERIVATIVE; HAPTEN; NITROBENZENE DERIVATIVE; PHOSPHONIC ACID 4 NITROBENZYL ESTER; PHOSPHONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL; ANTIBODY SPECIFICITY; ANTIBODY STRUCTURE; ARTICLE; BINDING SITE; CATALYSIS; CATALYST; CHEMICAL STRUCTURE; DEGRADATION; ENZYME SPECIFICITY; GENETIC PROCEDURES; GENETICS; KINETICS; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; MOLECULAR MODEL; MOUSE; REACTION ANALYSIS; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, CATALYTIC; BINDING SITES; CLONING, MOLECULAR; ESTERS; GLUTARATES; KINETICS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHONIC ACIDS; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

EID: 0034595395     PISSN: 09476539     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-3765(20000502)6:9<1656::AID-CHEM1656>3.3.CO;2-1     Document Type: Article

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