The relationship of sputum eosinophilia and sputum cell generation of IL-5

Journal of Allergy and Clinical Immunology

Volumn 106, Issue 6, 2000, Pages 1063-1069

  Liu, Lin Ying ^a   Swensen, Cheri A ^a   Kelly, Elizabeth A Becky ^b   Kita, Hirohito ^c   Busse, William W ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c MAYO CLINIC   (United States)

Author keywords

Allergy; Eosinophil IL 5; Sputum induction

Indexed keywords

INTERLEUKIN 5;

ADULT; ALLERGIC RHINITIS; ALLERGY; ANTIGEN RECOGNITION; ARTICLE; ASTHMA; CLINICAL ARTICLE; EOSINOPHIL; EOSINOPHILIA; FEMALE; HUMAN; LUNG LAVAGE; MALE; PRIORITY JOURNAL; SPUTUM ANALYSIS;

EID: 0034538065     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1067/mai.2000.110792     Document Type: Article

References (30)

1. Increased expression of eotaxin in bronchoalveolar lavage and airways of asthmatics contributes to the chemotaxis of eosinophils to the site of inflammation
2. Increases in eotaxin-positive cells in induced sputum from atopic asthmatic subjects after inhalational allergen challenge
3. Eotaxin and monocyte chemotactic protein-4 mRNA expression in small airways of asthmatic and nonasthmatic individuals
4. RANTES is a chemotactic and activating factor for human eosinophils
5. Cytokine concentrations in sputum of asthmatic patients
6. Kinetics of allergen-induced airway eosinophilic cytokine production and airway inflammation
7. The role of interleukin-5, interleukin-8 and RANTES in the chemotactic attraction of eosinophils to the allergic lung
8. Monocyte chemotactic protein-4 (MCP-4), a novel structural and functional analog of MCP-3 and eotaxin
9. Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma
10. Immediate and late airway response of allergic rhinitis patients to segmental antigen challenge. Characterization of eosinophil and mast cell mediators
11. Late response to allergen is associated with increased concentrations of tumor necrosis factor-α and IL-5 in induced sputum
12. IL-4 and IL-5 mRNA expression in induced sputum of asthmatic subjects: Comparison with bronchial wash
13. Increases in airway eosinophils and interleukin-5 with minimal bronchoconstriction during repeated low-dose allergen challenge in atopic asthmatics
14. Effect of inhaled interleukin-5 on airway hyperreactivity and eosinophilia in asthmatics
15. Effects of an antibody to interleukin-5 in a monkey model of asthma
16. Effect of anti-IL-5 and IL-5 on airway hyperreactivity and eosinophils in guinea pigs
17. Modulation of eosinophil chemotaxis by interleukin-5
18. The effect of segmental bronchoprovocation with allergen on airway lymphocyte function
19. The immediate and late allergic response to segmental bronchopulmonary provocation in asthma
20. Cellular and biochemical analysis of induced sputum from asthmatic and healthy subjects
21. Indices of airway inflammation in induced sputum: Reproducibility and validity of cell and fluid-phase measurements
22. IgA-induced eosthophil degranulation
23. Sputum in severe exacerbations of asthma. Kinetics of inflammation indices after prednisone treatment
24. Latephase asthmatic reaction to inhaled allergen is associated with early recruitment of eosinophils in the airways
25. The effect of IL-5 and eotaxin expression in the lung on eosinophil trafficking and degranulation and the induction of bronchial hyperreactivity
26. Neutrophilic inflammation in severn persistent asthma
27. Segmental antigen challenge increases fibronectin in bronchoalveolar lavage fluid
28. Relationship between interleukin-5 and eotaxin in regulating blood and tissue eosinophilia in mice
29. IL-5 is the predominant eosinophil-active cytokine in the antigen-induced pulmonary kate phase reaction
30. Eosinophil recruitment is associated with IL-5, but not RANTES, twenty-four hours after allergen challenge