Decrease in brain cytochrome P450 enzyme activities during infection and inflammation of the central nervous system

NeuroImmunoModulation

Volumn 8, Issue 3, 2000, Pages 142-147

  Monshouwer, Mario ^a,d   Agnello, Davide ^b   Ghezzi, Pietro ^b   Villa, Pia ^b,c  

^a UTRECHT UNIVERSITY   (Netherlands)

^b MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^c CNR   (Italy)

^d PFIZER INC   (United States)

Author keywords

Brain; Cytochrome P450; Experimental auto immune encephalomyelitis; Infection; Lipopolysaccharide

Indexed keywords

7 ETHOXYCOUMARIN DEETHYLASE; AMINOPYRINE N DEMETHYLASE; CYTOCHROME P450; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN METABOLISM; CENTRAL NERVOUS SYSTEM INFECTION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVITY; LIVER MICROSOME; MALE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD;

7-ALKOXYCOUMARIN O-DEALKYLASE; AMINOPYRINE N-DEMETHYLASE; ANIMALS; BRAIN; CYTOCHROME P-450 ENZYME SYSTEM; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENZYME ACTIVATION; INJECTIONS, INTRAVENTRICULAR; LIPOPOLYSACCHARIDES; MALE; MENINGITIS, BACTERIAL; MICROSOMES, LIVER; RATS; RATS, INBRED LEW; RATS, SPRAGUE-DAWLEY; SPINAL CORD; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034531740     PISSN: 10217401     EISSN: None     Source Type: Journal    
DOI: 10.1159/000054274     Document Type: Article

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