Association of the TNF-α-308 (G→A) polymorphism with self-reported history of childhood asthma

Human Genetics

Volumn 107, Issue 6, 2000, Pages 591-596

  Winchester, E C ^a   Millwood, I Y ^a   Rand, L ^a   Penny, M A ^a   Kessling, A M ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; DIPEPTIDYL CARBOXYPEPTIDASE; GUANINE; MAJOR HISTOCOMPATIBILITY ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; ASIAN; ASTHMA; CHILDHOOD DISEASE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE; GENE DELETION; GENE INSERTION; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC RISK; HUMAN; PRIORITY JOURNAL; RISK FACTOR; SOUTH ASIA; UNITED KINGDOM;

ADENINE; ASIA; ASTHMA; CHILD; ETHNIC GROUPS; FEMALE; GENOTYPE; GREAT BRITAIN; GUANINE; HUMANS; PEPTIDYL-DIPEPTIDASE A; POINT MUTATION; POLYMORPHISM, GENETIC; PREGNANCY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034531393     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004390000410     Document Type: Article

References (53)

1. Association of polymorphisms within the tumour necrosis factor (TNF) genes and childhood asthma
2. Gene-environment and gene-gene interaction studies in the molecular genetic analysis of asthma and atopy
3. New concepts in the pathogenesis of bronchial hyperresponsiveness and asthma
4. High frequency of a deletion polymorphism of the angiotensin-converting enzyme gene in asthma
5. Secretion of tumour necrosis factor alpha and lymphotoxin alpha in relation to polymorphisms in the TNF genes and HLA-DR alleles. Relevance for inflammatory bowel disease
6. Interleukin-4, -5, and -6 and tumour necrosis factor in normal and asthmatic airways: Evidence for the human mast cell as a source of these cytokines
7. Gene polymorphism at position -308 of the tumor-necrosis-factor-α (TNF-α) in multiple sclerosis and its influence on the regulation of TNF-α production
8. Relevance of the tumor necrosis factor alpha (TNF alpha) -308 promoter polymorphisms in TNF alpha gene regulation
9. Cytokines in symptomatic asthma airways
10. Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction
11. Polymorphism at the tumour necrosis factor locus and asthma
12. Linkage map of the human major histocompatibility complex including the tumour necrosis factor genes
13. Prevalence of tumour necrosis factor-α and angiotensin converting enzyme polymorphisms in mild/moderate and fatal/near-fatal asthma
14. The alliance of genes and environment in asthma and allergy
15. Angiotensin I-converting enzyme in human circulating mononuclear cells: Genetic polymorphism of expression in T-lymphocytes
16. Angiotensin I converting enzyme and the changes in our concept through the years
17. Lack of association between ACE gene polymorphisms and atopy and asthma in British and Japanese populations
18. Increased secretion of tumour necrosis factor alpha and interleukin-6 by alveolar macrophages consecutive to the development of the late asthmatic reaction
19. Mechanisms of cytokine-induced modulation of beta-adrenoceptor responsiveness in airway smooth muscle
20. Estimation of Hardy-Weinberg and pairwise disequilibrium in the apolipoprotein AI-CIII-AIV gene cluster
21. Association of 3 gene polymorphisms with atopic diseases
22. Structure of the angiotensin I-converting enzyme gene. Two alternate promoters correspond to evolutionary steps of a duplicated gene
23. Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: Relevance to genetic predisposition to systemic lupes erythematosus
24. Prostaglandins mediate bradykinin-induced reduction of exhaled nitric oxide in asthma
25. The -308 tumour necrosis factor-alpha promoter polymorphism effects transcription
26. Inactivation of bradykinin by angiotensin-converting enzyme and by carboxypeptidase N in human plasma
27. Association between -308 tumour necrosis factor promoter polymorphism and bronchial hyperreactivity in asthma
28. Candidate genes and a genome-wide search in Italian families with atopic asthmatic children
29. Activity of the renin-angiotensin system in acute severe asthma and the effect of angiotensin II on lung function
30. Tumour necrosis factor haplotypes and asthma
31. Genetics of asthma and inflammation: The status
32. Extended tumour necrosis factor/HLA-DR haplotypes and asthma in an Australian population sample
33. Renin-angiotensin system component gene polymorphism in Japanese bronchial asthma patients
34. A pitfall in the Association Study of ACE gene polymorphism
35. No independent association between a tumour necrosis factor alpha promoter polymorphism and insulin-dependent diabetes mellitus
36. An insertion/deletion polymorphism in the angiotensin-converting enzyme gene accounting for half the variance of serum enzyme levels
37. PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1)
38. Lack of association of angiotensin-converting enzyme (ACE). Gene insertion/deletion polymorphism with CAD in two Asian populations
39. The genetics of asthma
40. The genetics of asthma
41. Tumour necrosis factor alpha: A potential mediator of asthma
42. A common functional polymorphism (C→A substitution at position -863) in the promoter region of the tumour necrosis factor-α (TNF-α) gene associated with reduced circulating levels of TNF-α
43. -308 Tumour necrosis factor (TNF) polymorphism is not associated with survival in severe sepsis and is unrelated to lipopolysaccharide inducibility of the human TNF promoter
44. Asthma and TNF variants in Chinese and Malays
45. Complete sequence and gene map of a human major histocompatibility complex
46. Genetic polymorphism of the angiotensin-converting enzyme (ACE) in asthmatic patients
47. T cells and cytokines in bronchoalveolar lavage fluid after segmental allergen provocation in atopic asthma
48. Tumor necrosis factor-α-238 and -308 polymorphisms do not associate with traits related to obesity and insulin resistance
49. Complete characterization of disequilibrium at two loci
50. Single base polymorphism in the human tumour necrosis factor alpha (TNF-α) gene detectable by NcoI restriction of PCR product
51. A tumour necrosis factor alpha polymorphism is not associated with rheumatoid arthritis
52. Effects of a polymorphism in the tumour necrosis factor α promoter on transcriptional activation
53. HLA-DR and HLA-DP genotypes and immunoglobulin E responses to common major allergens