Tissue factor-dependent factor VIIa signaling

Trends in Cardiovascular Medicine

Volumn 10, Issue 2, 2000, Pages 47-52

  Petersen, Lars C ^a   Freskgård, Per Ola ^a   Ezban, Mirella ^a  

^a NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ANTICOAGULANT PROTEIN; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 7A; HIRUDIN; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; THROMBIN; THROMBOPLASTIN;

AMINO ACID COMPOSITION; ANIMAL CELL; BLOOD CLOTTING; CALCIUM MOBILIZATION; CELL STRAIN BHK; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE TRANSFER; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REPORTER GENE; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; BLOOD COAGULATION; FACTOR VIIA; HUMANS; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; THROMBOPLASTIN;

EID: 0034531150     PISSN: 10501738     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1050-1738(00)00041-4     Document Type: Review

References (45)

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7. H. Binding of factor VIIa to tissue factor on keratinocytes induces gene expression
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21. Requirement of Ras-GTP-Raf complexes for activation of Raf-1 by protein kinase C
22. Association of tissue factor with a γ chain homodimer of the IgE receptor type I in cultured human monocytes
23. Tissue factor cytoplasmic domain is multiply phosohorylated in vitro
24. Thrombin receptor activation elicits rapid protein tyrosine phosphorylation and stimulation of the Raf-1/MAP kinase pathway preceding delayed mitogenesis in cultured rat aortic smooth muscle cells
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29. Binding of factor VIIa to tissue factor induces alterations in gene expression in human fibroblast cells; upregulation of poly(A) polymerase
30. Factor VIIa and thrombin induce the expression of Cyr 61 and connective tissue growth factor, extracellular matrix signalling proteins that could act as possible downstream mediators in factor VII:tissue factor-induced signal transduction
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32. Exclusion of known protease activated receptors in factor VIIa-induced signal transduction
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34. Cellular consequences of the initiation of blood coagulation
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36. Tissue factor pathway inhibitor inhibits aortic smooth muscle cell migration induced by tissue factor-factor VIIa complex
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38. FactorVIIa-induced p44/42 mitogen-activated protein kinase activation requires the proteolytic activity of factor VIIa and is independent of the tissue factor cytoplasmic domain
39. Enhanced expression of urokinase receptor induced through the tissue factor-factor VIIa pathway in human pancreatic cancer
40. 100 Escherichia coli
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42. Factor VIIa/tissue factor-induced signalling via activation of Src-like Kinase, Phosphatidylinositol 3-kinase, and Rac
43. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
44. The cytoplasmic domain of tissue factor is phosphorylated by a protein kinase C-dependent mechanism