Expression of protein p27 is associated with progression and prognosis in laryngeal cancer

Laryngoscope

Volumn 109, Issue 5, 1999, Pages 815-820

  Fan, Guo Kang ^a   Fujieda, Shigeharu ^a   Sunaga, Hiroshi ^a   Tsuzuki, Hideaki ^a   Ito, Nobuhisa ^a   Saito, Hitoshi ^a  

^a UNIVERSITY OF FUKUI   (Japan)

Author keywords

Granulocyte colony stimulating factor receptor; Laryngeal cancer; p27; p53; Prognosis

Indexed keywords

COLONY STIMULATING FACTOR RECEPTOR; PROTEIN P27; PROTEIN P53;

ADULT; AGED; ARTICLE; CANCER GROWTH; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LARYNX CARCINOMA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; RETROSPECTIVE STUDY; SQUAMOUS CELL CARCINOMA; STATISTICAL ANALYSIS;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; CELL CYCLE PROTEINS; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASES; DISEASE PROGRESSION; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LARYNGEAL NEOPLASMS; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MIDDLE AGED; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RECEPTORS, GRANULOCYTE COLONY-STIMULATING FACTOR; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 0032912924     PISSN: 0023852X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005537-199905000-00025     Document Type: Article

References (21)

1. kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 1994;78:59-66.
2. kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients. Nature Med 1997;3:222-225.
3. kip1 protein: prognostic implications in primary breast cancer. Nature Med 1997;3:227-230.
4. Loda M, Cukor B, Tam SW, et al. Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Nature Med 1997;3:231-234.
5. Mori M, Mimori K, Shiraishi T, et al. p27 Expression and gastric carcinoma. Nature Med 1997;3:593.
6. Shin DM, Kim J, Ro JY, et al. Activation of p53 gene expression in premalignant lesion during head and neck tumor-igenesis. Cancer Res 1994;54:321-326.
7. Hirvikoski P, Kumpulainen E, Virtaniemi J, et al. p53 Expression and cell proliferation as prognostic factors in laryngeal squamous cell carcinoma. J Clin Oncol 1997;15:3111-3120.
8. Nadal A, Campo E, Pinto J, et al. p53 Expression in normal, dysplastic, and neoplastic laryngeal epithelium: absence of correlation with prognostic factors. J Pathol 1995;175:181-188.
9. Berdel WE, Denhauser-Riedl S, Steinhauser G, Winton EF. Various human hematopoietic growth factors (Interleukin-3, GM-CSF, G-CSF) stimulate clonal growth of nonhematopoietic tumor cells. Blood 1989;73:80-83.
10. Ohigashi T, Tachibana M, Tazaki H, Nakamura K. Bladder cancer cells express functional receptors for granulocyte-colony stimulating factor. J Urol 1992;147:283-286.
11. Tsuzuki H, Fujieda S, Sunaga H, Noda I, Saito H. Expression of granulocyte colony-stimulating factor receptor correlates with prognosis in oral and mesopharygeal carcinoma. Cancer Res 1998;58:794-800.
12. Ito T, Fujieda S, Tsuzuki H, et al. Bax expression is associated with tumor progression and clinical outcome in oral and oropharyngeal carcinoma. Cancer Letter in press.
13. kip1 induces cell cycle arrest and loss of cyclin-Cdk activity in human breast cancer cells. Oncogene 1997;14:2283-2289.
14. kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumor. Cell 1996;85:707-720.
15. Katayose Y, Kim M, Rakker ANS, Li Z, Cowan KH, Seth P. Promoting apoptosis: a novel activity associated with the cyclin-dependent kinase inhibitor p27. Cancer Res 1997;57: 5441-5445.
16. Fujieda S, Inuzuka M, Tanaka N, et al. Expression of p27 is associated with Bax expression and spontaneous apoptosis in oral and oropharyngeal carcinoma. Int J Cancer in press.
17. kip1 on adhesion-dependent resistance of tumor cells to anticancer agents. Nature Med 1996;2:1204-1210.
18. Pagano M, Tam SW, Theodoras AM, et al. Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science 1995; 269:682-685.
19. Kip1 accumulation during the cell cycle. Science 1996;271:1861-1864.
20. Kip1: chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors. Cancer Res 1995;55:1211-1214.
21. Kawamata N, Morosetti R, Miller CW, et al. Molecular analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in human malignancies. Cancer Res 1995;55:2266-2269.