Effects of enzyme inducers and inhibitor on the pharmacokinetics of intravenous 2-(allylthio)pyrazine, a new chemoprotective agent, in rats

Biopharmaceutics and Drug Disposition

Volumn 21, Issue 4, 2000, Pages 157-164

  Bu, Seong C ^a   Kim, Yoon G ^a   Kim, So H ^a   Lee, Myung G ^a  

^a Seoul National University   (South Korea)

Author keywords

2 AP; Enzyme inducers and inhibitor; Pharmacokinetics; Rats

Indexed keywords

2 (ALLYLTHIO)PYRAZINE; 3 METHYLCHOLANTHRENE; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 3A; DEXAMETHASONE; ENZYME INDUCING AGENT; ENZYME INHIBITOR; ETHOXYRESORUFIN DEETHYLASE; ISOENZYME; ISONIAZID; PENTOXYRESORUFIN DEALKYLASE; PHENOBARBITAL; PROADIFEN; PROTECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG METABOLISM; ENZYME METABOLISM; MALE; NONHUMAN; RAT;

AMINES; ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; DEXAMETHASONE; DRUG INTERACTIONS; ENZYME INDUCTION; ENZYME INHIBITORS; ISOENZYMES; ISONIAZID; MALE; PHENOBARBITAL; PROADIFEN; PYRAZINES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0034505131     PISSN: 01422782     EISSN: None     Source Type: Journal    
DOI: 10.1002/1099-081X(200005)21:4<157::AID-BDD226>3.0.CO;2-C     Document Type: Article

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