Involvement of cytochrome P4502E1 in the toxicity of dichloropropanol to rat hepatocyte cultures

Toxicology

Volumn 118, Issue 2-3, 1997, Pages 171-179

  Hammond, Alison H ^a   Fry, Jeffrey R ^a  

^a QUEEN S MEDICAL CENTRE   (United Kingdom)

Author keywords

Dichloropropanol; Diethyldithiocarbamate; Hepatocytes; Hepatotoxicity; isoniazid

Indexed keywords

ALLYL ALCOHOL; CYTOCHROME P450 ISOENZYME; DIETHYLDITHIOCARBAMIC ACID; GLUTATHIONE; ISONIAZID; ORGANOHALOGEN DERIVATIVE; PRECOCENE II;

ARTICLE; ENZYME ACTIVITY; IN VITRO STUDY; LIVER CELL CULTURE; LIVER TOXICITY; PRIORITY JOURNAL;

1-PROPANOL; ACETONE; ALPHA-CHLOROHYDRIN; ANALYSIS OF VARIANCE; ANIMALS; ANTIDOTES; BENZOPYRANS; CELL DEATH; CELLS, CULTURED; CHLOROHYDRINS; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; DITIOCARB; DRUG INTERACTIONS; ENZYME ACTIVATION; ENZYME INDUCTION; GLUTATHIONE; INSECTICIDES; ISONIAZID; L-LACTATE DEHYDROGENASE; LIVER; MALE; MUTAGENS; PLANTS; PROPANOLS; RATS; RATS, WISTAR;

EID: 0031588932     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(96)03604-9     Document Type: Article

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