Pore-forming colicins and their relatives

Current Topics in Microbiology and Immunology

Volumn 257, Issue , 2000, Pages 131-161

  Lakey, J H ^a   Slatin, S L ^b  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL TOXIN; COLICIN; COLICIN A; COLICIN E1;

BACTERIOPHAGE; CHANNEL GATING; HYDROPHOBICITY; MEMBRANE BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; REVIEW; TOXIN ANALYSIS; TOXIN STRUCTURE;

ANIMALS; BACTERIOPHAGES; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; COLICINS; ESCHERICHIA COLI PROTEINS; FUNGAL PROTEINS; HUMANS; HYDROGEN-ION CONCENTRATION; INTRACELLULAR MEMBRANES; ION CHANNELS; MODELS, MOLECULAR; RECEPTORS, CELL SURFACE;

BACTERIA (MICROORGANISMS);

EID: 0034469009     PISSN: 0070217X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (149)

1. Structure of the Escherichia coli TolB protein determined by MAD methods at 1.95Ȧ resolution
2. Functional domains of colicin A
3. A 136-amino-acid residue COOH-terminal fragment of colicin A is endowed with ionophoric activity
4. Protein import into Escherichia coli: Colicins A and E1 interact with a component of their translocation system
5. Colicin A unfolds during its translocation in Escherichia coli cells and spans the whole cell envelope when its pore has formed
6. FhuA, a transporter of the Escherichia coli outer membrane, is converted into a channel upon binding of bacteriophage T5
7. Distinct regions of the colicin A translocation domain are involved in the interaction with TolA and TolB proteins upon import into Escherichia coli
8. A new colicin that adsorbs to outer-membrane protein Tsx but is dependent on the TonB instead of the TolQ membrane-transport system
9. Structure and function of X-Pro dipeptide repeats in the TonB proteins of Salmonella typhimurium and Escherichia coli
10. Determination of the molecularity of the colicin E1 channel by stopped-flow ion flux kinetics
11. Purification of a small receptor-binding peptide from the central region of the colicin E1 molecule
12. Crystal structure of the outer membrane active transporter Fep A from Escherichia coli
13. Ion selectivity of colicin E1: II. Permeability to organic cations
14. Ion selectivity of colicin E1: III. Anion permeability
15. Structure of influenza hemagglutinin at the pH of membrane fusion
16. The structure of TolB, an essential component of the tol-dependent translocation system, and its protein-protein interaction with the translocation domain of colicin E9
17. Activation kinetics of the incorporation of colicin Ia into an artificial membrane: A Markov or a fractal model?
18. Role of the colicin A lysis protein in the expression of the colicin A operon
19. Lipoprotein nature of the colicin A lysis protein: Effect of amino acid substitutions at the site of modification and processing
20. Involvement of BtuB and OmpF proteins in the binding and uptake of colicin A
21. The acylated precursor form of the colicin A lysis protein is a natural substrate of the DegP protease
22. Hydrodynamic properties of colicin A. Existence of a high-affinity lipid-binding site and oligomerization at acid pH
23. The crystal structure of diphtheria toxin
24. Structure-function relationships for a voltage-dependent ion channel: Properties of COOH-terminal fragments of colicin E1
25. Gating processes of channels induced by colicin A, its C-terminal fragment and colicin E1, in planar lipid bilayers
26. Crystal structures explain functional properties of two E. coli porins
27. Structure and dynamics of the colicin E1 channel
28. Structure-function of the channel forming colicins
29. On a domain structure of colicin E1. A COOH-terminal peptide fragment active in membrane depolarization
30. Genetics of resistance to colicins in Escherichia coli K-12: Cross-resistance among colicins of group A
31. Genetics of resistance to colicins in Escherichia coli K-12: Cross-resistance among colicins of group B
32. Trojan peptides: The penetratin system for intracellular delivery
33. TolA central domain interacts with Escherichia coli porins
34. Circular dichroism and molecular modeling of the E. coli TolA periplasmic domains
35. Colicin pore-forming domains bind to Escherichia coli trimeric porins
36. Uncoupled steps of the colicin A pore formation demonstrated by disulfide bond engineering
37. Membrane topology of the colicin A pore-forming domain analyzed by disulfide bond engineering
38. Integration of the colicin A pore-forming domain into the cytoplasmic membrane of Escherichia coli
39. A mechanism for toxin insertion into membranes is suggested by the crystal structure of the channel-forming domain of colicin E1
40. Dynamic aspects of colicin n translocation through the Escherichia coli outer-membrane
41. Characterization of the receptor and translocator domains of colicin N
42. In vitro approaches to investigation of the early steps of colicin-OmpF interaction
43. The spontaneous insertion of proteins into and across membranes: The helical hairpin hypothesis
44. DNA-sequence analysis of 3 missense mutations affecting colicin-E3 bactericidal activity
45. The channel domain of colicin-a is inhibited by its immunity protein through direct interaction in the Escherichia coli inner membrane
46. Direct measurement of the association of a protein with a family of membrane receptors
47. Different sensitivities to acid denaturation within a family of proteins; Implications for acid unfolding and membrane translocation
48. Functional complementation between bacterial MDR-like export systems: Colicin V, alpha-hemolysin, and Erwinia protease
49. High levels of colicin resistance in Escherichia coli
50. Siderophore mediated iron transport; crystal structure of FhuA with bound lipopolysaccharide
51. Characterization of OmpF domains involved in Escherichia coli K-12 sensitivity to colicins A and N
52. An α-helical hydrophobic hairpin as a specific determinant in Protein-Protein interaction occurring in Escherichia coli colicin A and B immunity systems
53. Topology and function of the integral membrane protein conferring immunity to colicin A
54. Induction of colicin 1a at high temperature
55. Colicin A and the Tol proteins involved in its translocation are preferentially located in the contact sites between the inner and outer membranes of Escherichia coli cells
56. Bacteriocin 28b, a chromosomally encoded bacteriocin produced by most Serratia marcescens biotypes
57. Point mutations in a conserved region (TonB Box) of Escherichia coli outer membrane protein BtuB affect vitamin B12 transport
58. Mitomycin C and temperature induction of colicin B in the absence of deoxyribonucleic acid synthesis
59. Crystal structure of the two N-terminal domains of g3p from filamentous phage fd at 1.9Å: Evidence for conformational lability
60. Structural alignment of globins, phycocyanins and colicin-a
61. Probing the structure of the diphtheria toxin channel. Reactivity in planar lipid bilayer membranes of cysteine-substituted mutant channels with methanethiosulfonate derivatives
62. Sur la biosynthese d'une colicine et son mode d'action
63. Highly purified colicin E3 contains immunity protein
64. A hybrid toxin from bacteriophage f1 attachment protein and colicin E3 has altered cell receptor specificity
65. Translocation of inserted foreign epitopes by a channel-forming protein
66. Channel-forming colicin: Translocation (and other deviant behavior) associated with colicin Ia channel gating
67. The biology of E-colicins-Paradigms and paradoxes
68. Ligand-specific opening of a gated-porin channel in the outer membrane of living bacteria
69. Construction and characterization of pyocincolicin chimeric proteins
70. Induction of colicin production by high temperature or inhibition of protein synthesis
71. Transmembrane insertion of the colicin Ia hydrophobic hairpin
72. Translocation of the colicin Ia channel-forming domain: Where will it end?
73. Structural and mechanistic basis of immunity toward endonuclease colicins
74. Isolation and molecular and functional properties of the amino-terminal domain of colicin A
75. Characterization of colicin Ia and colicin IB. Chemical studies of protein structure
76. Interaction of colicin Ia with bacterial cells. Direct measurement of Ia-receptor interaction
77. Structure of TolC, the outer membrane component of the bacterial type I efflux system, derived from two-dimensional crystals
78. A novel approach to study the geometry of the water lumen of ion channels: Colicin Ia in planar lipid bilayers
79. Fluorescence energy transfer distance measurements using site-directed single cysteine mutants. The membrane insertion of colicin A
80. Site-directed fluorescence spectroscopy as a tool to study the membrane insertion of colicin A
81. Fluorescence energy transfer distance measurements: The hydrophobic helical hairpin of Colicin A in the membrane bound state
82. An 8-angstrom projected structure of FhuA, a "ligand-gated" channel of the Escherichia coli outer membrane
83. The membrane channel-forming colicin A: Synthesis, secretion, structure, action and immunity
84. Synthetic amphiphilic peptide models for protein ion channels
85. TolA: A membrane protein involved in colicin uptake contains an extended helical region
86. A single tryptic fragment of colicin E1 can form an ion channel: Stoichiometry confirms kinetics
87. Crystal structure of insecticidal delta-endotoxin from Bacillus thuringiensis at 2.5A resolution
88. Kinetic description of structural changes linked to membrane import of the colicin E1 channel protein
89. Unfolding pathway of the colicin E1 channel protein on a membrane surface
90. A very short peptide makes a voltage-dependent ion channel: The critical length of the channel domain on of colicin E1
91. Transmembrane signalling across the ligand-gated FhuA receptor; crystal strutcures of free and ferrichrome-bound states reveal allosteric changes
92. The structural basis of phage display elucidated by the crystal structure of the N terminal domains of g3p
93. Filamentous phage infection: Crystal structure of g3p in complex with its coreceptor, the C-terminal domain of TolA
94. Isolation, molecular and functional properties of the C-terminal domain of colicin A
95. Identification of a voltage-responsive segment of the potential-gated colicin E1 ion channel
96. Bcl-xL regulates apoptosis by heterodimerization-dependent and-independent mechanisms
97. X-ray and NMR structure of human BCL-X(L), an inhibitor of programmed cell-death
98. pH-dependent stability and membrane interaction of the pore-forming domain of colicin-A
99. Induction of colicin E1 synthesis by neocarzinostatin and bleomycin
100. Gating properties of channels formed by colicin Ia in planar lipid bilayer membranes
101. Translocation of the catalytic domain of diphtheria toxin across planar phospholipid bilayers by its own T domain
102. Structure of the membrane-pore-forming fragment of colicin A
103. Rendering a membrane-protein soluble in water-A common packing motif in bacterial protein toxins
104. Insights into membrane insertion based on studies of colicins
105. Refined structure of the pore-forming domain of colicin A at 2.4Å resolution
106. Formation of voltage dependent pores by colicin A
107. Voltage-dependent monomeric channel activity of colicin E1 in artificial membrane vesicles
108. Novel colicin-10-Assignment of 4 domains to tonb-dependent and tolc-dependent uptake via the tsx receptor and to pore formation
109. Strong function-related homology between the pore-forming colicin K and colicin 5
110. The Ton system can functionally replace the TolB protein in the uptake of mutated colicin U
111. Energy requirement for pullulanase secretion by the main terminal branch of the general secretory pathway
112. The ins and outs of colicins. Part II. Lethal action, immunity and ecological implications
113. Nucleotide sequencing of the structural gene for colicin N reveals homology between the catalytic, C-terminal domains of colicins A and B
114. Major transmembrane movement associated with colicin Ia channel gating
115. Discovery of critical Tol A-binding residues in the bactericidal toxin colicin N; a biophysical approach
116. Structural and functional organization of the Yersinia pestis bacteriocin pesticin gene cluster
117. Channels formed by colicin E1 in planar lipid bilayers are large and exhibit pH-dependent ion selectivity
118. Gating of a voltage-dependent channel (colicin E1) in planar lipid bilayers: Translocation of regions outside the channel-forming region
119. The C terminal of TolA is the coreceptor for filamentous phage infection of E. coli
120. Molecular mechanisms of colicin evolution
121. Molecular mechanisms of bacteriocin evolution
122. Formation of a gated channel by a ligand-specific transport protein in the bacterial outer membrane
123. Colicin K acts by forming voltage-dependent channels in phospholipid bilayer membranes
124. The TolA protein interacts with colicin E1 differently than with other group A colicins
125. On the nature of the unfolded intermediate in the in-vitro transition of the colicin E1 channel domain from the aqueous to the membrane phase
126. Transport across the outer membrane of Escherichia coli K12 via the FhuA receptor is regulated by the TonB protein of the cytoplasmic membrane
127. Purification and characterization of colicin E1
128. The diphtheria toxin channel-forming T domain translocates its own NH2-terminal region across planar bilayers
129. The diphtheria toxin channel-forming T domain translocates its own NH2-terminal region across planar bilayers
130. Structure-function relationships in diphtheria toxin channels I. Determining a minimal channel-forming domain
131. A protein-conducting channel in the endoplasmic reticulum
132. Colicin E1 in planar lipid bilayers
133. Gating of a voltage-dependent channel (colicin E1) in planar lipid bilayers: The role of protein translocation
134. Identification of a translocated segment in a voltage-dependent channel
135. Rapid invasion by colicinogenic Escherichia coli with novel immunity functions
136. Adventures in membrane protein topology. A study of the membrane bound state of colicin E1
137. A 'molten-globule' membrane-insertion intermediate of the pore-forming domain of colicin A
138. Role of acidic lipids in the translocation and channel activity of colicins A and N in Escherichia coli cells
139. Analysis of a cloned colicin Ib gene: Complete nucleotide sequence and implications for regulation of expression
140. Crystal structure of a colicin N fragment suggests a model for toxicity
141. A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
142. Pesticin displays muramidase activity
143. A structure-function analysis of BtuB, the E. coli vitamin B12 outer membrane transport protein
144. The to1 gene products and the import of macromolecules into Escherichia coli
145. Mechanism of action of colicin: Early events
146. Crystal structure of colicin Ia
147. Membrane-bound state of the colicin E1 channel domain as an extended two-dimensional array