Substrate-induced down-regulation of human type 2 deiodinase (hD2) is mediated through proteasomal degradation and requires interaction with the enzyme's active center

Endocrinology

Volumn 141, Issue 3, 2000, Pages 1127-1135

  Steinsapir, Jaime ^a   Bianco, Antonio C ^a   Buettner, Christoph ^a   Harney, John ^a   Larsen, P R ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CYCLOHEXIMIDE; CYSTEINE; IODIDE PEROXIDASE; PROTEASOME; SELENOCYSTEINE; THYROID HORMONE; UBIQUITIN;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEIODINATION; DOWN REGULATION; EMBRYO; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME MECHANISM; ENZYME REGULATION; ENZYME SUBSTRATE; HALF LIFE TIME; HUMAN; HUMAN CELL; MICHAELIS CONSTANT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION;

EID: 0034465486     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.141.3.7355     Document Type: Article

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