Focal adhesion kinase regulation by oxidative stress in different cell types

IUBMB Life

Volumn 50, Issue 4-5, 2000, Pages 291-299

  Mahdi, M H B ^a   Andrieu, V ^a   Pasquier, C ^a  

^a BICHAT HOSPITAL   (France)

Author keywords

Apoptosis; Cancer; Cell survival; Focal adhesion kinase; Reactive oxygen species; Superoxide anion; Tyrosine kinase

Indexed keywords

FOCAL ADHESION KINASE; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; AUTOPHOSPHORYLATION; CELL MIGRATION; CELL PROLIFERATION; CELL SPREADING; CELL STRUCTURE; CELL TYPE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME STRUCTURE; HUMAN; NONHUMAN; OXIDATIVE STRESS; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CELL DIVISION; CELL MOVEMENT; ENDOTHELIUM, VASCULAR; FOCAL ADHESION KINASE 1; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; OXIDATIVE STRESS; PROTEIN-TYROSINE KINASES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 0034456917     PISSN: 15216543     EISSN: None     Source Type: Journal    
DOI: 10.1080/15216540051081038     Document Type: Review

References (62)

1. Mesodermal defect in late phase of gastrulation by a targeted mutation of focal adhesion kinase, FAK
2. pp125FAK, a structurally distinctive protein-tyrosine kinase associated with focal adhesions
3. Oxidative stress induced in pathologies: The role of antioxidants
4. pp125FAK, a structurally distinctive protein-tyrosine kinase associated with focal adhesions
5. Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin
6. Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin
7. pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk
8. The evolution of free radicals and oxidative stress
9. Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions
10. Focal adhesion kinase in integrin-mediated signaling
11. Focal adhesion targeting: The critical determinant of FAK regulation and substrate phosphorylation
12. A mechanism for regulation of the adhesion-associated proteintyrosine kinase pp125FAK
13. Insulin-like growth factor I stimulates tyrosine phosphorylation of p130(Cas), focal adhesion kinase, and paxillin. Role of phosphatidylinositol 3′-kinase and formation of a p130(Cas). Crk complex
14. alpha2-Adrenoceptor stimulation promotes actin polymerization and focal adhesion in 3T3F442A and BFC-1beta preadipocytes
15. A transmembrane-anchored chimeric focal adhesion kinase is constitutively activated and phosphorylated at tyrosine residues identical to pp125FAK
16. Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src
17. Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
18. SH2- and SH3-mediated interactions between focal adhesion kinase and Src
19. Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation
20. Primary sequence of paxillin contains putative SH2 domain binding motifs and multiple LIM domains: Identification of a vinculin and pp125Fak-binding region
21. Control of adhesion-dependent cell survival by focal adhesion kinase
22. Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: Involvement of the Grb2, p130cas, and Nck adaptor proteins
23. pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk
24. Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice
25. Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase
26. Mesodermal defect in late phase of gastrulation by a targeted mutation of focal adhesion kinase, FAK
27. Tyrosine kinase cell signaling pathways of rat mesangial cells in 3-dimensional cultures: Response to fetal bovine serum and platelet-derived growth factor-BB
28. FAK integrates growth-factor and integrin signals to promote cell migration
29. Vascular endothelial growth factor (VEGF)-driven actin-based motility is mediated by VEGFR2 and requires concerted activation of stress-activated protein kinase 2 (SAPK2/p38) and geldanamycin-sensitive phosphorylation of focal adhesion kinase
30. Requirement of phosphatidylinositol 3-kinase in focal adhesion kinase-promoted cell migration
31. Potential role for focal adhesion kinase in migrating and proliferating keratinocytes near epidermal wounds and in culture
32. Control of smooth muscle cell proliferation and phenotype by integrin signaling through focal adhesion kinase
33. The COOH-terminal domain of the focal adhesion kinase induces loss of adhesion and cell death in human tumor cells
34. Focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer
35. Inhibition of pp125FAK in cultured fibroblasts results in apoptosis
36. Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis
37. Oxidative stress: Introductory remarks
38. The broad spectrum of responses to oxidants in proliferating cells: A new paradigm for oxidative stress
39. 2-induced T cell signal transduction
40. 2-induced T cell signal transduction
41. Activation of the mitogen-activated protein kinase signalling pathway in neutrophils. Role of oxidants
42. ROS stimulate reorganization of mesangial cell-collagen gels by tyrosine kinase signaling
43. Reactive oxygen intermediates activate NF-kB in a tyrosine kinase-dependent mechanism and in combination with vanadate activate the p561ck and p59fyn tyrosine kinases in human lymphocytes
44. Regulation of tyrosine phosphorylation in neutrophils by the NADPH oxidase. Role of reactive oxygen intermediates
45. Signal transduction in cell-matrix interactions
46. Sphingosylphosphorylcholine rapidly induces tyrosine phosphorylation of p125FAK and paxillin, rearrangement of the actin cytoskeleton and focal contact assembly. Requirement of p21rho in the signaling pathway
47. Oxidative stress-induced actin reorganization mediated by the p38 mitogen-activated protein kinase/heat shock protein 27 pathway in vascular endothelial cells
48. Intracellular signaling pathways in stellate cell activation
49. Peroxynitrite modulates tyrosine phosphorylation and phosphoinositide signalling in human neuroblastoma SH-SY5Y cells: Attenuated effects in human 132IN1 astrocytoma cells
50. A suppressive role of p125FAK protein tyrosine kinase in hydrogen peroxide-induced apoptosis of T98G cells
51. Reactive oxygen species activate focal adhesion kinase, paxillin, and p130cas tyrosine phosphorylation in endothelial cells
52. Hydrogen peroxide stimulates tyrosine phosphorylation of focal adhesion kinase in vascular endothelial cells
53. Muscarinic M3 and epidermal growth factor receptors activate mutually inhibitory signaling cascades in human neuroblastoma SH-SY5Y cells
54. Oxidative stress affects cytoskeletal structure and cell-matrix interactions in cells from an ocular tissue: The trabecular meshwork
55. FAK is the upstream signal protein of the phosphatidylinositol 3-kinase-Akt survival pathway in hydrogen peroxide-induced apoptosis of a human glioblastoma cell line
56. A suppressive role of p125FAK protein tyrosine kinase in hydrogen peroxide-induced apoptosis of T98G cells
57. Anti-apoptotic role of focal adhesion kinase (FAK). Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line, HL-60
58. Suppression of ultraviolet irradiation-induced apoptosis by overexpression of focal adhesion kinase in Madin-Darby canine kidney cells
59. Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals
60. Caspase-mediated cleavage of focal adhesion kinase pp125FAK and disassembly of focal adhesions in human endothelial cell apoptosis
61. Caspases cleave focal adhesion kinase during apoptosis to generate a FRNK-like polypeptide
62. Targeted proteolysis of the focal adhesion kinase pp125 FAK during c-MYC-induced apoptosis is suppressed by integrin signalling