Automated genotyping of single-nucleotide polymorphisms by extension of fluorescently labelled primers: Analysis of individual and pooled DNA samples.

Balkan Journal of Medical Genetics

Volumn 3, Issue 4, 2000, Pages 23-28

  Kirov, G ^a   Stephens, M ^a   Williams, N ^a   O'Donovan, M ^a   Owen, M ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Fluorescent; Genotyping; Method; Primer extension; SNP

Indexed keywords

DNA;

ANALYTIC METHOD; ARTICLE; ECONOMIC ASPECT; FLUORESCENCE ANALYSIS; GENE FREQUENCY; GENE MUTATION; GENE POOL; GENE SEQUENCE; GENETIC ANALYSIS; GENOTYPE; HEALTH CARE COST; HUMAN; LABORATORY DIAGNOSIS; MASS SPECTROMETRY; PRIMED IN SITU LABELING; RELIABILITY; SAMPLE; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 0034454582     PISSN: 13110160     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. SNP Consortium database
2. Database of single nucleotide polymorphisms
3. Genetic epidemiology of single-nucleotide polymorphisms
4. Prospects for whole-genome linkage disequilibrium mapping of common disease genes
5. Nature Genetics editorial. SNP attack on complex traits
6. Single nucleotide polymorphism determination using primer extension and time-of-flight mass spectrometry
7. A new MALDI-TOF based mini-sequencing assay for genotyping of SNPS
8. Large-scale discovery and genotyping of single-nucleotide polymorphisms in the mouse
9. Parallel genotyping of human SNPs using generic high-density oligonucleotide tag arrays
10. Determination of single-nucleotide polymorphisms by real-time pyrophosphate DNA sequencing
11. Pyrosequencing
12. Single-nucleotide polymorphism analysis by pyrosequencing
13. Allelic discrimination using fluorogenic probes and the 5′ nuclease assay
14. High-throughput SNP allele-frequency determination in pooled DNA samples by kinetic PCR
15. Rapid detection of mitochondrial sequence polymorphisms using multiplex solid-phase fluorescent minisequencing
16. Multiplex, fluorescent, solid-phase minisequencing for efficient screening of DNA sequence variation
17. Pooled genotyping of microsatellite markers in parent-offspring trios
18. Cheap, accurate and rapid allele frequency estimation of single nucleotide polymorphisms by primer extension and DHPLC in DNA pools
19. Screening ABCG1, the human homologue of the Drosophila white gene, for polymorphisms and association with bipolar affective disorder
20. Association mapping of disease loci, by use of a pooled DNA genomic screen
21. Allele frequency distributions in pooled DNA samples: Applications to mapping complex disease genes
22. Determining SNP allele frequencies in DNA pools