Donitriptan, a unique high-efficacy 5-HT1B/1D agonist: Key features and acute antimigraine potential

CNS Drug Reviews

Volumn 6, Issue 4, 2000, Pages 278-289

  John, Gareth W ^a   Perez, Michel ^a   Pauwels, Petrus J ^a   Le Grand, Bruno ^a   Verscheure, Yvan ^a   Colpaert, Francis C ^a  

^a INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

5 HT1B 1D receptors; F 11356; F 12640; Intrinsic activity; Migraine; Triptans

Indexed keywords

ANTIMIGRAINE AGENT; CALCIUM ION; CYCLIC AMP; DONITRIPTAN; FORSKOLIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); NARATRIPTAN; POTASSIUM ION; RECEPTOR SUBTYPE; SEROTONIN; SEROTONIN 1 AGONIST; SEROTONIN 1B AGONIST; SEROTONIN 1B RECEPTOR; SEROTONIN 1D RECEPTOR; SEROTONIN DERIVATIVE; SUMATRIPTAN; TRYPTAMINE; UNCLASSIFIED DRUG; ZOLMITRIPTAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; CALCIUM SIGNALING; CAROTID ARTERY FLOW; DOSE RESPONSE; DRUG EFFICACY; DRUG POTENCY; DRUG SELECTIVITY; GUINEA PIG; HUMAN; MIGRAINE; NONHUMAN; POTASSIUM CURRENT; RAT; RECEPTOR AFFINITY; RECEPTOR INTRINSIC ACTIVITY; REVIEW; SAPHENOUS VEIN; SWINE; TRIGEMINUS GANGLION; VASOCONSTRICTION;

EID: 0034444749     PISSN: 1080563X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1527-3458.2000.tb00153.x     Document Type: Review

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