Native 5-HT(1B) receptors expressed in OK cells display dual coupling to elevation of intracellular calcium concentrations and inhibition of adenylate cyclase

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 358, Issue 5, 1998, Pages 503-508

  Zgombick, John M ^a   Branchek, Theresa A ^a  

^a H LUNDBECK A S   (Denmark)

Author keywords

5 HT(1B) receptor; Cyclic AMP; Intracellular calcium; OK cells; Receptor reserve

Indexed keywords

3 (1,2,5,6 TETRAHYDRO 4 PYRIDYL)PYRROLO[3,2 B]PYRIDIN 5 ONE; ADENYLATE CYCLASE; CALCIUM; CYANOPINDOLOL; CYANOPINDOLOL I 125; CYCLIC AMP; FORSKOLIN; GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPRENALINE; METITEPINE; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; PERTUSSIS TOXIN; SEROTONIN 1B RECEPTOR; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; 3 (1,2,5,6 TETRAHYDROPYRID 4 YL)PYRROLO(3,2 B)PYRID 5 ONE; 3-(1,2,5,6-TETRAHYDROPYRID-4-YL)PYRROLO(3,2-B)PYRID-5-ONE; ADENYLATE CYCLASE TOXIN; BORDETELLA VIRULENCE FACTOR; DRUG DERIVATIVE; OXADIAZOLE DERIVATIVE; PINDOLOL; PIPERAZINE DERIVATIVE; PYRIDINE DERIVATIVE; PYRROLE DERIVATIVE; SEROTONIN; SEROTONIN RECEPTOR;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL MEMBRANE; CONCENTRATION RESPONSE; DISSOCIATION CONSTANT; ENZYME INHIBITION; NONHUMAN; OPOSSUM; SECOND MESSENGER; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; KIDNEY; METABOLISM; PHYSIOLOGY; RADIOASSAY;

ADENYLATE CYCLASE; ADENYLATE CYCLASE TOXIN; ANIMALS; CALCIUM; CELL LINE; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; FORSKOLIN; KIDNEY; METHIOTHEPIN; OPOSSUMS; OXADIAZOLES; PERTUSSIS TOXIN; PINDOLOL; PIPERAZINES; PYRIDINES; PYRROLES; RADIOLIGAND ASSAY; RECEPTOR, SEROTONIN, 5-HT1B; RECEPTORS, SEROTONIN; SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; VIRULENCE FACTORS, BORDETELLA;

EID: 0031593434     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00005285     Document Type: Article

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