Predisposition to cancer and radiosensitivity

Genetics and Molecular Biology

Volumn 23, Issue 4, 2000, Pages 1101-1105

  Pichierri, P ^a   Franchitto, A ^a   Palitti, F ^a  

^a UNIVERSITY OF TUSCIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYSIS; ASSAY; CANCER SUSCEPTIBILITY; CELL CYCLE; CELL CYCLE G2 PHASE; CELL LABELING; CELL POPULATION; CELL SURVIVAL; CHROMOSOME; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DONOR; FIBROBLAST; HUMAN; HUMAN CELL; INCIDENCE; IRRADIATION; METAPHASE; MICRONUCLEUS TEST; PERIPHERAL LYMPHOCYTE; RADIATION; RADIOSENSITIVITY; SAMPLE; SCORING SYSTEM; SHORT SURVEY;

EID: 0034431519     PISSN: 14154757     EISSN: None     Source Type: Journal    
DOI: 10.1590/S1415-47572000000400058     Document Type: Short Survey

References (28)

1. Barber, J.B., Burrill, W., Spreadborough, A.R., Levine, E., Warren, C., Kiltie, A.E., Roberts, S.A. and Scott, D. (2000). Relationship between in vitro chromosomal radiosensitivity of peripheral blood lymphocytes and the expression of normal tissue damage following radiotherapy for breast cancer. Radiother. Oncol. 55: 179-186.
2. Cleaver, J.E. (1968). Defective repair replication of DNA in xeroderma pigmentosum. Nature 218: 652-656.
3. Cleaver, J.E. (1969). Xeroderma pigmentosum: a human disease in which an initial stage of DNA repair is defective. Proc. Natl. Acad. Sci. USA 63: 428-435.
4. Cleaver, J.E. and Kraemer, K.H. (1989). Xeroderma pigmentosum. In: The Metabolic Basis of Inherited Disease (Scriver, C.R., Beaudet, A.L., Sly, W.S. and Valle, D., eds.). 6th edn., Vol. II. McGraw-Hill, New York, pp. 2946-2971.
5. Critchlow, S.E. and Jackson, S.P. (1998). DNA end-joining: from yeast to man. Trends Biochem. Sci. 23: 394-398s.
6. Darroudi, F., Vyas, R.C., Vermeulen, S. and Natarajan, A.T. (1995). G2 radiosensitivity of cells derived from cancer-prone individuals. Mutat. Res. 328: 83-90.
7. Digweed, M., Reis, A. and Sperling, K. (1999). Nijmegen breakage syndrome: consequences of defective DNA double strand break repair. Bioessays 21: 649-656.
8. Easton, D.F. (1994). Cancer risks in A-T heterozygotes. Int. J. Radiat. Biol. 66: S177-S182.
9. Ford, D. and Easton, D.F. (1996). The breast-ovarian cancer syndrome and BRCA1. In: Genetic Predisposition to Cancer (Eeles, R.A., Ponder, B.A.J., Easton, D.F. and Horwhich, A., eds.). Chapman and Hall, London, pp. 239-252.
10. Fujiwara, Y. and Tatsumi, M. (1977). Cross-link repair in human cells and its possible defect in Fanconi's anemia cells. J. Mol. Biol. 113: 635-649.
11. Gebhart, E., Schinzel, M. and Ruprecht, K.W. (1985). Cytogenetic studies using various clastogens in two patients with Werner syndrome and control individuals. Hum. Genet. 70: 324-327.
12. Goldgar, D.E., Strattonn, M.R. and Eles, R.A. (1996). Familial breast cancer. In: Genetic Predisposition to Cancer (Eeles, R.A., Ponder, B.A.J., Easton, D.F. and Horwhich, A., eds.). Chapman and Hall, London, pp. 227-238.
13. Haber, J.E. (2000). Recombination: a frank view of exchanges and vice versa. Curr. Opin. Cell Biol. 12: 286-296.
14. Higurashi, M. and Conen, P.E. (1973). In vitro chromosomal radiosensitivity in "chromosomal breakage syndromes". Cancer 32: 380-383.
15. Jeggo, P., Singleton, B., Beamish, H. and Priestley, A. (1999). Double strand break rejoining by the Ku-dependent mechanism of non-homologous end-joining. C.R. Acad. Sci. III 322: 109-112.
16. Kanaar, R., Hoeijmakers, J.H. and van Gent, D.C. (1998). Molecular mechanisms of DNA double strand break repair. Trends Cell. Biol. 8: 483-489.
17. Lavin, M.F. and Khanna, K.K. (1999). ATM: the protein encoded by the gene mutated in the radiosensitive syndrome ataxia-telangiectasia. Int. J. Radiat. Biol. 75: 1201-1214.
18. Little, J.B., Nichols, W.W., Troilo, P., Nagasawa, H. and Strong, L.C. (1989). Radiation sensitivity of cell strains from families with genetic disorders predisposing to radiation-induced cancer. Cancer Res. 49: 4705-4714.
19. Palitti, F., Pichierri, P., Franchitto, A., Proietti De Santis, L. and Mosesso, P. (1999). Chromosome radiosensitivity in human G2 lymphocytes and cell-cycle progression. Int. J. Radiat. Biol. 75: 621-627.
20. Pastink, A. and Lohman, P.H. (1999). Repair and consequences of double-strand breaks in DNA. Mutat. Res. 428: 141-156.
21. Rigaud, O., Guedeney, G., Duranton, I., Leroy, A., Doloy, M.T. and Magdelenat, H. (1990). Genotoxic effects of radiotherapy and chemotherapy on the circulating lymphocytes of breast cancer patients. II. Alteration of DNA repair and chromosome radiosensitivity. Mutat. Res. 242: 25-35.
22. Roberts, S.A., Spreadborough, A.R., Bulman, B., Barber, J.B., Evans, D.G. and Scott, D. (1999). Heritability of cellular radiosensitivity: a marker of low-penetrance predisposition genes in breast cancer? Am. J. Hum. Genet. 65: 784-794.
23. Samouhos, E. (1983). Chromosomes, cancer and radiosensitivity. Am. J. Clin. Oncol. 6: 503-506.
24. Sanford, K.K., Parshad, R., Gantt, R., Tarone, R.E., Jones, G.M. and Price, F.M. (1989). Factors affecting and significance of G2 chromatin radiosensitivity in predisposition to cancer. Int. J. Radiat. Biol. 55: 963-981.
25. Scott, D., Spreadborough, A., Levine, E. and Roberts, S.A. (1994). Genetic predisposition in breast cancer. Lancet 344: 1444.
26. Scott, D., Spreadborough, A.R., Jones, L.A., Roberts, S.A. and Moore, C.J. (1996). Chromosomal radiosensitivity in G2-phase lymphocytes as an indicator of cancer predisposition. Radiat. Res. 145: 3-16.
27. Scott, D., Barber, J.B., Levine, E.L., Burrill, W. and Roberts, S.A. (1998). Radiation-induced micronucleus induction in lymphocytes identifies a high frequency of radiosensitive cases among breast cancer patients: a test for predisposition? Br. J. Cancer 77: 614-620.
28. Takata, M., Sasaki, M.S., Sonoda, E., Morrison, C., Hashimoto, M., Utsumi, H., Yamaguchi-Iwai, Y., Shinohara, A. and Takeda, S. (1998). Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity of vertebrate cells. EMBO J.: 17: 5497-5508.