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Journal of Chromatography B: Biomedical Sciences and Applications

Volumn 748, Issue 1, 2000, Pages 281-293

Mass directed peak selection, an efficient method of drug metabolite identification using directly coupled liquid chromatography-mass spectrometry-nuclear magnetic resonance spectroscopy

(7) Dear, G J a Plumb, R S a Sweatman, B C a Ayrton, J a Lindon, J C b Nicholson, J K b Ismail, I M a

a GLAXOSMITHKLINE (United Kingdom)

b IMPERIAL COLLEGE LONDON (United Kingdom)

Author keywords

Drug metabolites; Peak selection

Indexed keywords

2 ETHYL 7 FLUORO 3 OXO 3,4 DIHYDRO 2H QUINOXALINE CARBOXYLIC ACID ISOPROPYLESTER; 4 AMINO 1 (2,6 DIFLUOROBENZYL) 1H 1,2,3 TRIAZOLO[4,5 C]PYRIDINE; DRUG METABOLITE; GI 262663; GI 265080; GW 420867; PYRIDINE DERIVATIVE; QUINOXALINE DERIVATIVE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CONTROLLED STUDY; DOG; DRUG DETERMINATION; DRUG STRUCTURE; DRUG URINE LEVEL; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULAR WEIGHT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; RAT; SPECTROMETER;

CHROMATOGRAPHY, LIQUID; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; PHARMACEUTICAL PREPARATIONS;

EID: 0034306734 PISSN: 13872273 EISSN: None Source Type: Journal
DOI: 10.1016/S0378-4347(00)00291-7 Document Type: Article

Times cited : (40)

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