A rapid and efficient approach to metabolite identification using nuclear magnetic resonance spectroscopy, liquid chromatography/mass spectrometry and liquid chromatography/nuclear magnetic resonance spectroscopy/sequential mass spectrometry

Rapid Communications in Mass Spectrometry

Volumn 12, Issue 24, 1998, Pages 2023-2030

  Dear, G J ^a   Ayrton, J ^a   Plumb, R ^a   Sweatman, B C ^a   Ismail, I M ^a   Fraser, I J ^a   Mutch, P J ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MAGNETIC RESONANCE SPECTROMETERS; MASS SPECTROMETRY; METABOLITES; NUCLEAR MAGNETIC RESONANCE;

HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; ION TRAPS; LIQUID CHROMATOGRAPHY - MASS SPECTROMETRIES; LIQUID CHROMATOGRAPHY-NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; METABOLITE IDENTIFICATION; NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS; STRUCTURAL ELUCIDATION; WEIGHT INFORMATION;

NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

EID: 0032413197     PISSN: 09514198     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1097-0231(19981230)12:24<2023::aid-rcm431>3.0.co;2-6     Document Type: Article

References (25)

1. G. G. Gibson and P. Skett, Introduction to Drug Metabolism, Chapman and Hall, London, New York (1986).
2. M. Mitchard, in Drug Metabolism in Man, J. W. Gorrod and A. H. Beckett (Eds), p175, Taylor and Francis, London (1978).
3. D. J. Harvey, Mass Spectrom. 9, 303 (1987).
4. D. J. Harvey, Mass Spectrom. 10, 273 (1989).
5. W. E. Siefert Jr., A. Ballatore and R. M. Caprioli, Rapid Commun. Mass Spectrom. 3, 117 (1989).
6. E. de Hoffman, J. Mass Spectrom. 31, 129 (1996).
7. M. Kaibaf, J. H. Lamb, S. Naylor, K. Pattichis and J. W. Gorrod, Anal. Chim. Acta 247, 151 (1991).
8. S. Naylor, M. Kaibaf, J. H. Lamb, M. Jahanshahi and J. W. Gorrod, Biol. Mass Spectrom. 21, 165 (1992).
9. G. J. Dear, J. C. Harrelson, A. E. Jones, T. E. Johnson and S. Pleasance, Rapid Commun. Mass Spectrom. 9, 1457 (1995).
10. G. J. Dear, I. J. Fraser, D. K. Patel, J. Long and S. Pleasance, J Chromatogr. A 794, 27 (1998).
11. M. Spraul, M. Hoffman and P. Belton (Eds), Magnetic Resonance Food Science, Royal Society of Chemistry, Cambridge, p 77 (1995).
12. M. Spraul, M. Hoffman, J. C. Lindon, R. D. Farrant, M. J. Seddon, J. K. Nicholoson and I. D. Wilson, NMR BioMed. 7, 295 (1994).
13. J. C. Lindon, J. K. Nicholson, U. G. Sidelmann and I. D. Wilson Drug Met. Reviews 29 (3), 705 (1997).
14. F. S. Pullen, A. G. Swanson, M. J. Newmann and D. S. Richards, Rapid Commun. Mass Spectrom. 9, 1003 (1995).
15. R. M. Holt, M. J. Newmann, F. S. Pullen, D. S. Richards and A. G. Swanson, J. Mass Spectrom. 32, 64 (1997).
16. K. I. Burton, J. R. Everett, M. J. Newmann, F. S. Pullen, D. S. Richards and A. G. Swanson, J. Pharmaceutical Biomed. Anal. 15, 1903, (1997).
17. J. P. Shocker, S. E. Unger, I. D. Wilson, P. J. Foxall, J. K. Nicholson and J. C. Lindon, Anal. Chem. 68, 4431 (1997).
18. M. Spraul, M. Hoffman, J. C. Lindon, J. K. Nicholson and I. D. Wilson, Analytical Proceedings 30, 390 (1993).
19. B. C. Sweatman, R. D. Farrant, P. N. Sanderson, I. Philippe, S. R. Salman, J. K. Nicholson and J. C. Lindon, J. Magn. Reson. Anal. 1, 9 (1995).
20. J. P. Chervet, M. Ursen and J. P. Salzmann, Anal. Chem. 68, 1507 (1996).
21. K. Vanhoutte, W. Van Dongen and E. L. Esmans, Rapid Commun. Mass Spectrom. 12, 15 (1998).
22. K. Vanhoutte, W. Van Dongen, I. Hoes, F. Lemiere, E. L. Esmans, H. Van Onckelen, E. Van den Eeckhout, R. E. J. van Soest and A. J. Hudson, Anal. Chem. 69, 3161 (1997).
23. D. L. Olson, M. E. Lacey and J. V. Sweedler, Anal., Chemistry News and Features April 1, (1998).
24. K. Pusecker, J. Schewitz, P. Gforer, L. Tseng, K. Albert and E. Bayer, Anal. Chem. 70, 3280 (1998).
25. R. N. Warriner, A. S. Craze, D. E. Games and S. J. Lane, Rapid Commun. Mass Spectrom. 12, 1143 (1998).