Obesity: Are we any closer to identifying causes and effective treatments?

Trends in Pharmacological Sciences

Volumn 21, Issue 9, 2000, Pages 334-336

  MacDonald, Ian A ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DEXFENFLURAMINE; FENFLURAMINE; SIBUTRAMINE; TETRAHYDROLIPSTATIN; TRIACYLGLYCEROL LIPASE;

BODY FAT; BODY MASS; CALORIC INTAKE; COGNITIVE THERAPY; COMORBIDITY; DIET; ENERGY BALANCE; ENERGY EXPENDITURE; HEREDITY; HUMAN; LIFESTYLE; OBESITY; PRIORITY JOURNAL; RISK FACTOR; SHORT SURVEY; THERMOGENESIS; WEIGHT REDUCTION;

EID: 0034283685     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(00)01528-5     Document Type: Review

References (17)

1. Obesity: Preventing and Managing the Global Epidemic. 1998;WHO, Geneva.
2. Prentice A.M., Jebb S.A. Obesity in Britain: gluttony or sloth? Br. Med. J. 311:1995;437-439.
3. Stubbs R.J.et al. Covert manipulation of dietary fat and energy density: effect on substrate flux and food intake in men eating ad libitum. Am. J. Clin. Nutr. 62:1995;316-329.
4. McGoey B.B.et al. Effect of weight loss on musculoskeletal pain in the morbidly obese. J. Bone Joint Surg. Ser. A. 728:1990;1322-1323.
5. Seidell J.C. Epidemiology: definition and classification of obesity. Kopelman P.G., Stock M.J. Clinical Obesity. 1998;1-17 Blackwell.
6. Colditz G. Economic costs of obesity. Am. J. Clin. Nutr. 55:1992;503S-507S.
7. Lean M.E.J.et al. Waist circumference indicates the need for weight measurement. Br. Med. J. 311:1995;158-161.
8. Obesity in Scotland: Integrating Prevention With Weight Management. 1996;Royal College of Physicians, Scotland.
9. Rissanen A.et al. Treatment of hypertension in obese patients: efficacy and feasibility of weight and salt reduction programs. Acta Med. Scand. 218:1995;149-156.
10. Wing R.R.et al. Long-term effects of modest weight loss in type 2 diabetic patients. Ann. Int. Med. 147:1987;1749-1753.
11. Williamson D.F.et al. Prospective study of intentional weight loss and mortality in never-smoking overweight US white women aged 40-64 years. Am. J. Epidemiol. 141:1995;1128-1141.
12. Wardle J., Rapoport L. Cognitive-behavioural treatment of obesity. Kopelman P.G., Stock M.J. Clinical Obesity. 1998;1-17 Blackwell.
13. Campfield L.A.et al. Strategies and potential molecular targets for obesity treatment. Science. 280:1998;1383-1387.
14. Huszar D.et al. Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell. 88:1997;131-141.
15. Woods S.C.et al. Signals that regulate food intake and energy homeostasis. Science. 280:1998;1378-1383.
16. Moran T.H.et al. Blockade of type A, but not type B, CCK receptors postpones satiety in rhesus monkeys. Am. J. Physiol. 265:1993;R620-R624.
17. Leibowitz S.F. Differential functions of hypothalamic galanin cell groups in the regulation of eating and body weight. Ann. New York Acad. Sci. 863:1998;206-220.