Heterogeneous effects of IL-2 on collagen-induced arthritis

Journal of Immunology

Volumn 165, Issue 3, 2000, Pages 1557-1563

  Thornton, Sherry ^a   Boivin, Gregory P ^b   Kim, Kwang N ^a   Finkelman, Fred D ^b,c   Hirsch, Raphael ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G2A; RECOMBINANT INTERLEUKIN 2;

ANIMAL CELL; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; AUTOIMMUNE DISEASE; COLLAGEN METABOLISM; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE EXACERBATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SCORING SYSTEM;

EID: 0034254305     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.3.1557     Document Type: Article

References (55)

1. Feldmann, M., F. M. Brennan, and R. N. Maini. 1996. Role of cytokines in rheumatoid arthritis. Annu. Rev. Immunol. 14:397.
2. Bessis, N., M. C. Boissier, P. Ferrara, T. Blankenstein, D. Fradelizi, and C. Fournier. 1996. Attenuation of collagen-induced arthritis in mice by treatment with vector cells engineered to secrete interleukin-13. J. Immunol. 26:2399.
3. Hesse, M., S. Bayrak, and A. Mitchison. 1996. Protective major histocompatibility complex genes and the role of interleukin-4 in collagen-induced arthritis. Eur. J. Immunol. 26:3234.
4. Horsfall, A. C., D. M. Butler, L. Marinova, P. J. Warden, R. O. Williams, R. N. Maini, and M. Feldmann. 1997. Suppression of collagen-induced arthritis by continuous administration of IL-4. J. Immunol. 159:5687.
5. Joosten, L. A. B., E. Lubberts, P. Durez, M. M. A. Helsen, M. J. M. Jacobs, M. Goldman, and W. B. van den Berg. 1997. Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis. Arthritis Rheum. 40:249.
6. Tanaka, Y., T. Otsuka, T. Hotokebuchi, H. Miyahara, H. Nakashima, S. Kuga, Y. Nemoto, H. Niiro, and Y. Niho. 1996. Effect of IL-10 on collagen-induced arthritis in mice. Inflamm. Res. 45:283.
7. Walmsley, M., P. D. Katsikis, E. Abney, S. Parry, R. O. Williams, R. N. Maini, and M. Feldmann. 1996. Interleukin-10 inhibition of the progression of established collagen-induced arthritis. Arthritis Rheum. 39:495.
8. Allen, J. B., H. L. Wong, G. L. Costa, M. J. Bienkowski, and S. M. Wahl. 1993. Suppression of monocyte function and differential regulation of IL-1 and IL-1ra by IL-4 contribute to resolution of experimental arthritis. J. Immunol. 151:4344.
9. Chomarat, P., J. Banchereau, and P. Miossec. 1995. Differential effects of interleukins 10 and 4 on the production of interleukin-6 by blood and synovium monocytes in rheumatoid arthritis. Arthritis Rheum. 38:1046.
10. Isomaki, P., R. Lukkainen, R. Saario, P. Toivanen, and J. Punnonen. 1996. Interleukin-10 functions as an antiinflammatory cytokine in rheumatiod synovium. Arthritis Rheum. 39:386.
11. Katsikas, P. D., C.-Q. Chu, F. M. Brennan, R. N. Maini, and M. Feldmann. 1994. Immunoregulatory role of interleukin 10 in rheumatoid arthritis. J. Exp. Med. 179:1517.
12. van Roon, J. A., J. L. van Roy, F. H. Gmelig-Meyling, F. P. Lafeber, and J. W. Bijlsma. 1996. Prevention and reversal of cartilage degradation in rheumatoid arthritis by interleukin-10 and interleukin-4. Arthritis Rheum. 39:829.
13. Dolhain, R. J., A. N. van der Heiden, N. T. ter Haar, F. C. Breedveld, and A. M. Miltenburg. 1996. Shift toward T lymphocytes with a T helper 1 cytokine-secretion profile in the joints of patients with rheumatoid arthritis. Arthritis Rheum. 39:1961.
14. Cooper, S. M., S. Sriram, and G. E. Ranges. 1988. Suppression of murine collagen-induced arthritis with monoclonal anti-1a antibodies and augmentation with IFN-γ. J. Immunnl. 141:1958.
15. Mauritz, N. J., R. Holmdahl, R. Jonsson, P. H. Van der Meide, A. Scheynius, and L. Klareskog. 1988. Treatment with γ-interferon triggers the onset of collagen arthritis in mice. Arthritis Rheum. 31:1297.
16. Banerjee, S., B. Wei, K. Hillman, H. S. Luthra, and C. S. David. 1988. Immunosuppression of collagen-induced arthritis in mice with an anti-1L-2 receptor antibody. J. Immunol. 141:1150.
17. Firestein, G. S., W. D. Xu, K. Townsend, D. Broide, J. Alvaro-Gracia, A. Glasebrook, and N. J. Zvaifler. 1988. Cytokines in chronic inflammatory arthritis. J. Exp. Med. 168:1573.
18. Thornton, S., G. P. Boivin, Y. Ma, and R. Hirsch. 1999. Association of the course of collagen-induced arthritis with distinct patterns of cytokine and chemokine messenger RNA expression. Arthritis Rheum. 42:1109.
19. Kanik, K. S., E. Hagiwara, C. H. Yarboro, H. R. Schumacher, R. L. Wilder, and D. M. Klinman. 1998. Distinct patterns of cytokine secretion characterize new onset synovitis versus chronic rheumatoid arthritis. J. Rheumatol. 25:16.
20. Sadlack, B., H. Merz, H. Schorle, A. Schimpl, A. C. Feller, and I. Horak. 1993. Ulcerative colitis-like disease in mice with a disrupted interleuken-2 gene. Cell 75:253.
21. Horak, I. 1995. Immunodeficiency in IL-2-knockout mice. Clin. Immunol. Immunopathol. 76:S172.
22. Hughes, C., J. A. Wolos, E. H. Giannini, and R. Hirsch. 1994. Induction of T helper cell hyporesponsiveness in an experimental model of autoimmunity by using nonmitogenic anti-CD3 monoclonal antibody. J. Immunol. 153:3319.
23. Finkelman, F. D., and S. C. Morris. 1999. Development of an assay to measure in vivo cytokine production in the mouse. Int. Immunol. 11:1811.
24. Chastagner, P., I. L. Moreau, Y. Jacques, T. Tanaka, M. Miyasaka, M. Kondo, K. Sugamura, and J. Theze. 1996. Lack of intermediate-affinity interleukin-2 receptor in mice leads to dependence on interleukin-2 receptor α, β and γ chain expression for T cell growth. Eur. J. Immunol. 26:201.
25. Froussard, P., D. L. Jankovic, P. Chastagner, and J. Theze. 1991. Induction of mouse p55 interleukin-2 receptor gene expression by IL-2 and IL-4 and characterization of its transcription initiation sites. Mol. Immunol. 28:87.
26. Tada, Y., K. Nagasawa, A. Ho, F. Morito, O. Ushiyama, N. Suzuki, H. Ohta, and T. W. Mak. 1999. CD28-deficient mice are highly resistant to collagen-induced arthritis. J. Immunol. 162:203.
27. Wooley, P. H., H. S. Luthra, M. M. Griffiths, J. M. Stuart, A. Huse, and C. S. David. 1985. Type II collagen-induced arthritis in mice. IV. Variations in immunogenetic regulation provide evidence for multiple arthritogenic epitopes or the collagen molecule. J. Immunol. 135:2443.
28. Goldschmidt, T. J., M. Andersson, V. Malmstrom, and R. Holmdahl. 1992. Activated type II collagen reactive T cells are not eliminated by in vivo anti-CD4 treatment: implications for therapeutic approaches on autoimmune arthritis, Immunobiology 184:359.
29. Durie, F. H., R. A. Fava, T. M. Foy, A. Aruffo, J. A. Ledbetter, and R. J. Noelle. 1993. Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40. Science 261:1328.
30. + cell subset shifts and autoimmunity in the BXSB mouse by murine CT4LA41g. J. Immunol 156:1262.
31. Stuart, J. M., A. S. Townes, and A. H. Kang. 1982. Nature and specificity of the immune response to collagen in type II collagen-induced arthritis in mice. J. Clin. Invest. 69:673.
32. Theze, J., P. M. Alzari, and J. Bertoglio. 1996. Interleukin 2 and its receptors: recent advances and new immunological functions. Immunol. Today 17:481.
33. Plows, D., G. Kontogeorgos, and G. Kollias. 1999. Mice lacking mature T and B lymphocytes develop arthritic lesions after immunization with type 11 collagen. J. Immunol. 162:1018.
34. Doncarli, A., L. M. Stasiuk, C. Fournier, and O. Abehsira-Amar. 1997. Conversion in vivo from an early dominant Th0/Th1 response to a Th2 phenotype during the development of collagen-induced arthritis. Eur. J Immunol. 27:1451.
35. Contractor, N. V., H. Bassiri, T. Reya, A. Y. Park, D. C. Baumgart, M. A. Wasik, S. G. Emerson, and S. R. Carding. 1998. Lymphoid hyperplasia, autoimmunity, and compromised intestinal intraepithelial lymphocyte development in colitis-free gnotobiotic IL-2-deficient mice. J. Immunol. 160:385.
36. Klebb, G., I. B. Autenrieth, H. Haber, E. Gillert, B. Sadlack, K. A. Smith, and I. Horak. 1996. Interleukin-2 is indispensable for development of immunological self-tolerance. Clin. Immunol. Immunopathol. 81:282.
37. Zhang, E., T. Poul, S. Bulfone-Paus, J. Wachtlin, U. Kunzendorf, and F. Hoffmann. 1998. Prolongation of corneal allograft survival by an interleukin-2 immunoglobulin fusion protein in mice. Graefe's Arch. Clin. Exp. Ophthalmol. 236:486.
38. Zheng, L., C. L. Trageser, D. M. Willerford, and M. J. Lenardo. 1998. T cell growth cytokines cause the superinduction of molecules mediating antigen-induced T lymphocyte death. J Immunol. 160:763.
39. Critchfield, J. M., M. K. Racke, J. C. Zuniga-Pflucker, B. Cannella, C. S. Raine, J. Goverman, and M. J. Lenardo. 1994. T cell deletion in high antigen dose therapy of autoimmune encephalomyelitis. Science 263:1139.
40. Oyaizu, N., T. W. McCloskey, S. Than, R. Hu, V. S. Kalyanaraman, and S. Pahwa. 1994. Cross-linking of CD4 molecules upregulates Fas antigen expression in lymphocytes by inducing interferon-γ and tumor necrosis factor-α secretion. Blood 84:2622.
41. + T cell activation and IFN-γ production. J. Immunol. 161:2848.
42. + human marrow cells is induced by interferon γ and tumor necrosis factor α and potentiates cytokine-mediated hematopoietic suppression in vitro. Blood 85:3183.
43. + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 188:287.
44. Sakaguchi, S., N. Sakaguchi, M. Asano, M. Itoh, and M. Toda. 1995. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor a-chains (CD25): breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 155:1151.
45. Boissier, M. C., G. Chiocchia, N. Bessis, J. Hajnal, G. Garotta, F. Nicoletti, and C. Fournier. 1995. Biphasic effect of interferon-γ in murine collagen-induced arthritis. Eur. J. Immunol. 25:1184.
46. Manoury-Schwartz, B., G. Chiocchia, N. Bessis, O. Abehsira-Amar, F. Batteux, S. Muller, S. Huang, M. C. Boissier, and C. Fournier. 1997. High susceptibility to collagen-induced arthritis in mice lacking IFN-γ receptors. J. Immunol. 158: 5501.
47. Kageyama, Y., Y. Koide, A. Yoshida, M. Uchijima, T. Arai, S. Miyamoto, T. Ozeki, M. Hiyoshi, K. Kushida, and T. Inoue. 1998. Reduced susceptibility to collagen-induced arthritis in mice deficient in IFN-γ receptor. J. Immunol. 161: 1542.
48. Vermeire, K., H. Heremans, M. Vandeputte, S. Huang, A. Billiau, and P. Matthys. 1997. Accelerated collagen-induced arthritis in IFN-γ receptor-deficient mice. J. Immunol. 158:5507.
49. Jacob, C. O., J. Holoshitz, P. Van der Meide, S. Strober, and H. O. McDevitt. 1989. Heterogeneous effects of IFN-γ in adjuvant arthritis. J. Immunol. 142:1500.
50. Weigent, D. A., G. J. Stanton, and H. M. Johnson. 1983. Interleukin 2 enhances natural killer cell activity through induction of γ interferon. Infect. Immun. 41: 992.
51. Sayers, T., H. Rossiter, J. Chung, A. Hren, and D. Armerding. 1985. In vivo activation of murine natural killer cell functions by human recombinant DNA interleukin 2. Immunobiology 169:303.
52. Mussener, A., M. J. Litton, E. Lindroos, and L. Klareskog. 1997. Cytokine production in synovial tissue of mice with collagen-induced arthritis (ClA). Clin. Exp. Immunol. 107:485.
53. Buchan, G., K. Barrett, T. Fujita, T. Taniguchi, R. Maini, and M. Feldmann. 1988. Detection of activated T cell products in the rheumatoid joint using cDNA probes to interleukin 2 (IL-2) IL-2 receptor and IFN-γ. Clin. Exp. Immunol. 71:295.
54. John, S., A. Myerscough, A. Marlow, A. Hajeer, A. Silman, W. Ollier, and J. Worthington. 1998. Linkage of cytokine genes to rheumatoid arthritis: evidence of genetic heterogeneity. Ann. Rheum. Dis. 57:361.
55. Encinas, J. A., L. S. Wicker, L. B. Peterson, A. Mukasa, C. Teuscher, R. Sobel, H. L. Weiner, C. E. Seidman, J. G. Seidman, and V. K. Kuchroo. 1999. QTL influencing autoimmune diabetes and encephalomyelitis map to a 0.15-cM region containing 112. Nat. Genet. 21:158.