Heregulin β1 induces the down regulation and the ubiquitin-proteasome degradation pathway of p185(HER2) oncoprotein

FEBS Letters

Volumn 422, Issue 2, 1998, Pages 129-131

  Magnifico, A ^a   Tagliabue, E ^a   Ardini, E ^a   Casalini, P ^a   Colnaghi, M I ^a   Menard S ^a,b  

^a Division of Medical Oncology B   (Italy)

^b NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Down modulation; p185(HER2) oncoprotein; Proteasome enzyme; Ubiquitination

Indexed keywords

MEMBRANE PROTEIN; NEU DIFFERENTIATION FACTOR; ONCOPROTEIN; PROTEASOME; PROTEIN INHIBITOR; PROTEIN TYROSINE KINASE; ADENOSINE TRIPHOSPHATE; BENZOQUINONE DERIVATIVE; CARRIER PROTEIN; CYSTEINE PROTEINASE; ENZYME INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GENISTEIN; GLYCOPROTEIN; HERBIMYCIN; HEREGULIN BETA1; MACROCYCLIC LACTAM; MULTIENZYME COMPLEX; QUINONE DERIVATIVE; RECOMBINANT PROTEIN; UBIQUITIN;

ARTICLE; BREAST CARCINOMA; CELL CULTURE; CONTROLLED STUDY; ENDOCYTOSIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; BIOSYNTHESIS; BREAST TUMOR; FEMALE; KINETICS; METABOLISM; PHOSPHORYLATION;

ADENOSINE TRIPHOSPHATE; BENZOQUINONES; BREAST NEOPLASMS; CARRIER PROTEINS; CYSTEINE ENDOPEPTIDASES; ENZYME INHIBITORS; FEMALE; GENISTEIN; GLYCOPROTEINS; HUMANS; KINETICS; LACTAMS, MACROCYCLIC; MULTIENZYME COMPLEXES; NEUREGULIN-1; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; QUINONES; RECEPTOR, ERBB-2; RECOMBINANT PROTEINS; TUMOR CELLS, CULTURED; UBIQUITINS;

EID: 0032579005     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(97)01612-8     Document Type: Article

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