Evidence that separate neural circuits the nucleus accumbens encode cocaine versus 'natural' (water and food) reward

Journal of Neuroscience

Volumn 20, Issue 11, 2000, Pages 4255-4266

  Carelli, Regina M ^a   Ijames, Stephanie G ^a   Crumling, Alison J ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Cocaine; Food; Nucleus accumbens; Reward; Self administration; Water

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; ELECTROPHYSIOLOGY; INFORMATION PROCESSING; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; REINFORCEMENT; REWARD;

EID: 0034212626     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-11-04255.2000     Document Type: Article

References (64)

1. Alexander GE, Crutcher MD (1990) Functional architecture of basal ganglia circuits: neural substrates of parallel processing. Trends Neurosci 13:266-271.
2. Alexander GE, DeLong MR, Strick PL (1986) Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci 9:357-381.
3. Apicella P, Ljungberg T, Scarnati E, Schultz W (1991) Responses to reward in monkey dorsal and ventral striatum. Exp Brain Res 85:491-500.
4. Bardo MT (1998) Neuropharmacological mechanisms of drug reward: beyond dopamine in the nucleus accumbens. Crit Rev Neurobiol 12:37-67.
5. Bassareo V, Di Chiara G (1999) Differential responsiveness of dopamine transmission to food-stimuli in nucleus accumbens shell/core compartments. Neuroscience 89:637-641.
6. Bowman EM, Aigner TG, Richmond BJ (1996) Neural signals in the monkey ventral striatum related to motivation for juice and cocaine rewards. J Neurophysiol 75:1061-1073.
7. Brog JS, Salyapongse A, Deutch AY, Zahm DS (1993) The patterns of afferent innervation of the core and shell in the "accumbens" part of the rat ventral striatum: immunohistochemical detection of retrogradely transported fluoro-gold. J Comp Neurol 338:255-278.
8. Caine SB, Kooh GF (1994) Effects of mesolimbic dopamine depiction on responding maintained by cocaine and food. J Exp Anal Behav 61:213-221.
9. Carelli RM, Deadwyler SA (1994) A comparison of nucleus accumbens neuronal firing patterns during cocaine self-administration and water reinforcement in rats. J Neurosci 14:7735-7746.
10. Carelli RM, Deadwyler SA (1996) Dose-dependent transitions in nucleus accumbens cell firing and behavioral responding during cocaine self-administration sessions in rats. J Pharmacol Exp Ther 277:385-393.
11. Carelli RM, Deadwyler SA (1997) Cellular mechanisms underlying reinforcement-related processing in the nucleus accumbens: electrophysiological studies in behaving animals. Pharmacol Biochem Behav 57:495-504.
12. Carelli RM, Ijames S, Konstantopoulos J, Deadwyler SA (1999) Examination of factors mediating the transition to behaviorally correlated nucleus accumbens cell firing during cocaine self-administration in rats. Behav Brain Res 104:127-139.
13. Chang JY, Sawyer SF, Lee RS, Woodward DJ (1994) Electrophysiological and pharmacological evidence for the role of the nucleus accumbens in cocaine self-administration in freely moving rats. J Neurosci 14:1224-1244.
14. Chang JY, Janak PH, Woodward DJ (1998) Comparison of mesocorticolimbic neuronal responses during cocaine and heroin self-administration in freely moving rats. J Neurosci 18:3098-3115.
15. Childress AR, McElgin W, Mozley D, O'Brien CP (1998) PET imaging of cue-induced and no-drug craving states. Soc Neurosci Abstr 24:1967.
16. Cousins MS, Atherton A, Turner L, Salamone JD (1996) Nucleus accumbens dopamine depletions alter relative response allocation in a T-maze cost/benefit task. Behav Brain Res 74:189-197.
17. Di Chiara G (1995) The role of dopamine in drug abuse viewed from the perspective of its role in motivation. Drug Alcohol Depend 38:95-137.
18. Everitt BJ (1990) Sexual motivation: a neural and behavioural analysis of the mechanisms underlying appetitive and copulatory responses in male rats. Neurosci Biobehav Rev 14:217-232.
19. Glowa JR, Fantegrossi WE (1997) Effects of dopaminergic drugs on food- and cocaine-maintained responding. IV. Continuous cocaine infusions. Drug Alcohol Depend 45:71-79.
20. Glowa JR, Wojnicki FHE (1996) Effects of drug on food- and cocaine-maintained responding. III. Dopaminergic antagonists. Psychopharmacology 128:351-358.
21. Green JD (1958) A simple microelectrode for recording from the central nervous system. Nature 182:962.
22. Groenewegen HJ, Berendse HW, Meredith GE, Haber SN, Voorn P, Walters JG, Lohman AHM (1991) Functional anatomy of the ventral, limbic system-innervated striatum. In: The mesolimbic dopamine system: from motivation to action. (Willner P, Scheel-Kruger J, eds), pp 19-59. New York: Wiley.
23. Groenewegen HJ, Wright CI, Beijer AV (1996) The nucleus accumbens: gateway for limbic structures to reach the motor system? Prog Brain Res 107:485-511.
24. Heimer L, Zahm DS, Alheid GF (1995) Basal ganglia. In: The rat nervous system, Ed 2. (Paxinos G, ed), pp 579-628. San Diego: Academic.
25. Heimer L, Alheid GF, de Olmos JS, Groenewegen HJ, Haber SN, Harlan RE, Zahm DS (1997) The accumbens: beyond the core-shell dichotomy. J Neuropsychiatry Clin Neurosci 9:354-381.
26. Hoebel BG (1997) Neuroscience and appetitive behavior research: 25 years. Appetite 29:119-133.
27. Hollerman JR, Tremblay L, Schultz W (1998) Influence of reward expectation on behavior-related neuronal activity in primate striatum. J Neurophysiol 80:947-963.
28. Kelley AE (1999) Functional specificity of ventral striatal compartments in appetitive behaviors. Ann NY Acad Sci 877:71-90.
29. Kelley AE, Swanson CJ (1997) Feeding induced by blockade of AMPA and kainate receptors within the ventral striatum: a microinfusion mapping study. Behav Brain Res 89:107-113.
30. Koob GF (1998) Circuits, drugs, and drug addiction. Adv Pharmacol 42:978-982.
31. Koob GF, Nestler EJ (1997) The neurobiology of drug addiction. J Neuropsychiatry Clin Neurosci 9:482-497.
32. Lee RS, Koob GF, Henriksen SJ (1998) Electrophysiological responses of nucleus accumbens neurons to novelty stimuli and exploratory behavior in the awake, unrestrained rat. Brain Res 799:317-322.
33. Mello NK, Negus SS (1998) Effects of kappa opioid agonists on cocaine-and food-maintained responding by rhesus monkeys. J Pharmacol Exp Ther 286:812-824.
34. Nicolelis MAL (1999) Methods for neural ensemble recordings. Boca Raton, FL: CRC.
35. Nicolelis MAL, Ghazanfar AA, Faggin BM, Votaw S, Oliveira LMO (1997) Reconstructing the engram: simultaneous, multisite, many single neuron recordings. Neuron 18:529-537.
36. Paxinos G, Watson C (1997) The rat brain in stereotaxic coordinates, Compact third edition. San Diego: Academic.
37. Pennartz CM, Groenewegen HJ, Lopes da Silva FH (1994) The nucleus accumbens as a complex of functionally distinct neuronal ensembles: an integration of behavioral, elcctrophysiological and anatomical data. Prog Neurobiol 42:719-761.
38. Peoples LL, West MO (1996) Phasic firing of single neurons in the rat nucleus accumbens correlated with the timing of intravenous cocaine self-administration. J Neurosci 16:3459-3473.
39. Peoples LL, Gee F, Bibi R, West MO (1998) Phasic firing time locked to cocaine self-infusion and locomotion: dissociable firing patterns of single nucleus accumbens neurons in the rat. J Neurosci 18:7588-7598.
40. Pfaus JG, Damsma G, Nomikos GG, Wenkstern DG, Blaha CD, Phillips AG, Fibiger HC (1990) Sexual behavior enhances central dopamine transmission in the male rat. Brain Res 530:345-348.
41. Rada P, Mark GP, Hoebel BG (1998) Galanin in the hypothalamus raises dopamine and lowers acetylcholine release in the nucleus accumbens: a possible mechanism for hypothalamic initiation of feeding behavior. Brain Res 798:1-6.
42. Richardson NR, Gratton A (1996) Behavior-relevant changes in nucleus accumbens dopamine transmission elicited by food reinforcement: an electrochemical study in rat. J Neurosci 16:8160-8169.
43. Salamone JD, Cousins MS, Snyder BJ (1997) Behavioral functions of nucleus accumbens dopamine: empirical and conceptual problems with the anhedonia hypothesis. Neurosci Biobehav Rev 21:341-359.
44. Schultz W (1998) Predictive reward signal of dopamine neurons. J Neurophysiol 80:1-27.
45. Schultz W, Apicella P, Scarnati E, Ljungberg T (1992) Neuronal activity in monkey ventral striatum related to expectation of reward. J Neurosci 12:4595-4610.
46. Schultz W, Dayan P, Montague PR (1997) A neural substrate of prediction and reward. Science 275:1593-1599.
47. Sokolowski JD, Salamone JD (1998) The role of accumbens dopamine in lever pressing and response allocation: effects of 6-OHDA injected into the core and dorsomedial shell. Pharmacol Biochem Behav 59:557-566.
48. Stewart J, deWit H, Eikelboom R (1984) Role of unconditioned and conditioned drug effects in the self-administration of opiates and stimulants. Psychol Rev 91:251-268.
49. Stratford TR, Kelley AE (1997) GABA in the nucleus accumbens shell participates in the central regulation of feeding behavior. J Neurosci 17:4434-4440.
50. Stratford TR, Swanson CJ, Kelley A (1998) Specific changes in food intake elicited by blockade or activation of glutamate receptors in the nucleus accumbens shell. Behav Brain Res 93:43-50.
51. Swanson CJ, Heath S, Stratford TR, Kelley AE (1997) Differential behavioral responses to dopaminergic stimulation of nucleus accumbens subregions in the rat. Pharmacol Biochem Behav 58:933-945.
52. Taber MT, Fibiger HC (1997) Feeding-evoked dopamine release in the nucleus accumbens: regulation by glutaminergic mechanisms. Neuroscience 76:1105-1112.
53. Tran-Nguyen LTL, Baker DA, Grote KA, Solano J, Neisewander JL (1999) Serotonin depletion attenuates cocaine-seeking behavior in rats. Psychopharmacology 146:60-66.
54. Tremblay L, Hollerman JR, Schultz W (1998) Modifications of reward expectation-related neuronal activity during learning in primate striaturn. J Neurophysiol 80:964-977.
55. Weissenborn R, Robbins TW, Everitt BJ (1997) Effects of medial prefrontal or anterior cingulate cortex lesions on responding for cocaine under fixed-ratio and second-order schedules of reinforcement in rats. Psychopharmacology 134:242-257.
56. Wenkstern D, Pfaus JG, Fibiger HC (1993) Dopamine transmission increases in the nucleus accumbens of male rats during their first exposure to sexually receptive female rats. Brain Res 618:41-46.
57. Wilson C, Nomikos GG, Collu M, Fibiger HC (1995) Dopaminergic correlates of motivated behavior: Importance of drive. J Neurosci 15:5169-5178.
58. Wise RA (1982) Common neural basis for brain stimulation reward, drug reward, and food reward. In: The neural basis of feeding and reward (Hoebel BG and Novin D, eds), pp 445-454. Brunswick, ME: Haer Institute.
59. Wise RA (1983) Brain neuronal systems mediating reward processes. In: The neurobiology of opiate reward processes. (Smith JE, Lane JD, eds), pp 405-437. New York: Elsevier.
60. Wise RA (1997) Drug self-administration viewed as ingestive behavior. Appetite 28:1-5.
61. Wise RA (1998) Drug-activation of brain reward pathways. Drug Alcohol Depend 51:13-22.
62. Wojnicki FHE, Rothman RB, Rice KC, Glowa JR (1999) Effects of phentermine on responding maintained under multiple fixed-ratio schedules of food and cocaine presentation in the rhesus monkey. J Pharmacol Exp Ther 288:550-560.
63. Wright CI, Beijcr VJ, Groenewegen HJ (1996) Basal amygdaloid complex afferents to the rat nucleus accumbens are compartmentally organized. J Neurosci 16:1877-1893.
64. Zahm DS, Brog JS (1992) Commentary: on the significance of subterritorics in the "accumbens" part of the rat ventral striatum. Neuroscience 50:751-767.