X-linked genetic factors regulate hematopoietic stem-cell kinetics in females

Blood

Volumn 95, Issue 7, 2000, Pages 2449-2451

  Christensen, Kaare ^a   Kristiansen, Marianne ^b   Hagen Larsen, Heidi ^b   Skylthe, Axel ^b   Bathum, Lise ^b   Jeune, Bernard ^b   Andersen Ranberg, Karen ^b   Vaupel, James W ^b   Ørstavik, Karen Helene ^b  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AGED; AGING; ARTICLE; CELL KINETICS; CHROMOSOME MOSAICISM; CONTROLLED STUDY; FEMALE; HEMATOPOIETIC STEM CELL; HEREDITY; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SEX DIFFERENCE; X CHROMOSOME INACTIVATION; X CHROMOSOME LINKAGE;

EID: 0034176876     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v95.7.2449     Document Type: Article

References (21)

1. Busque L, Mio R, Mattioli J, et al. Nonrandom X-inactivation patterns in normal females: lyonization ratios vary with age. Blood. 1996;88:59.
2. Gale RE, Fielding AK, Harrison CN, Linch DC. Acquired skewing of X-chromosome inactivation patterns in myeloid cells of the elderly suggests stochastic clonal loss with age. Br J Haematol. 1997;98:512.
3. Champion KM, Gilbert JG, Asimakopoulos FA, Hinshelwood S, Green AR. Clonal haemopoiesis in normal elderly women: implications for the myeloproliferative disorders and myelodysplastic syndromes. Br J Haematol. 1997;97:920.
4. Abkowitz JL, Catlin SN, Guttorp P. Evidence that hematopoiesis may be a stochastic process in vivo. Nat Med. 1996;2:190.
5. Abkowitz JL, Taboada M, Shelton GH, Catlin SN, Guttorp P, Kiklevich JV. An X chromosome gene regulates hematopoietic stem cell kinetics. Proc Natl Acad Sci U S A. 1998;95:3862.
6. Nance WE. Do twin Lyons have larger spots? Am J Hum Genet. 1990;46:646.
7. Hall JG. Twins and twinning. Am J Med Genet. 1996;61:202.
8. Monteiro J, Derom C, Vlietinck R, Kohn N, Lesser M, Gregersen PK. Commitment to X inactivation precedas the twinning event in monochorionic MZ twins. Am J Hum Genet. 1998;63:339.
9. Christensen K, Gaist D, Jeune B, Vaupel JW. A tooth per child? Lancet. 1998;352:204.
10. Allen RC, Zoghbi HY, Moseley AB, Rosenblatt HM, Belmont JW. Methylation of HpaII and HhaI sites near the polymorphic CAG repeat in the human androgen-receptor gene correlates with X chromosome inactivation. Am J Hum Genet. 1992;51:1229.
11. Orstavik KH, Orstavik RE, Naumova AK, et al. X chromosome inactivation in carriers of Barth syndrome. Am J Hum Genet. 1998;63:1457.
12. Orstavik KH, Barg K. Skewed X chromosome inactivation pattern in healthy females 83 years or older [abstract]. Eur J Hum Genet. 1998;6(suppl 1):A1165.
13. Belmont JW. Genetic control of X inactivation and processes leading to X-inactivation skewing. Am J Hum Genet. 1996;58:1101.
14. Naumova AK, Olien L, Bird LM, et al. Genetic mapping of X-linked loci involved in skewing of X chromosome inactivation in the human. Eur J Hum Genet. 1998;6:552.
15. Fearon ER, Kohn DB, Winkelstein JA, Vogelstein B, Blaese RM. Carrier detection in the Wiskott-Aldrich syndrome. Blood. 1988;72:1735.
16. Nyhan WL, Bakay B, Connor JD, Marks JF, Keele DK. Hemizygous expression of glucose-6-phosphate dehydrogenase in erythrocytes of heterozygotes for the Lesch-Nyhan syndrome. Proc Natl Acad Sci U S A. 1970;85:214.
17. Puck JM. The timing of twinning: more insights from X inactivation. Am J Hum Genet. 1998;63: 327.
18. Filosa S, Giacometti N, Wangwei C, et al. Somatic-cell selection is a major determinant of the blood-cell phenotype in heterozygotes for glucose-6-phosphate dehydrogenase mutations causing severe enzyme deficiency. Am J Hum Genet. 1996;59:887.
19. Luzzatto L, Usanga EA, Bienzle U, Esan GF, Fusuan FA. Imbalance in X-chromosome expression: evidence for a human X-linked gene affecting growth of hemopoietic cells. Science. 1979; 205:1418.
20. Vaupel JW, Carey JR, Christensen K, et al. Biodemographic trajectories of longevity. Science. 1998;280:855.
21. Payevsky VA, Vysotsky VG, Yefremov VD, Markovets MY, Morozov YG, Shapoval AP. Sex-specific survival rales in birds. Zhurnal Obschei Biologii. 1997;58:5.