Cloning and expression analysis of a novel gene, RP42, mapping to an autism susceptibility locus on 6q16

Genomics

Volumn 65, Issue 1, 2000, Pages 70-74

  Mas, Christophe ^a   Bourgeois, Francine ^a   Bulfone, Alessandro ^b   Levacher, Béatrice ^a   Mugnier, Claude ^c   Simonneau, Michel ^a  

^a HÔPITAL ROBERT DEBRÉ   (France)

^b TELETHON INSTITUTE OF GENETICS AND MEDICINE TIGEM   (Italy)

^c UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA;

AMINO ACID SEQUENCE; ARTICLE; AUTISM; BRAIN DEVELOPMENT; CHROMOSOME 6Q; DISEASE PREDISPOSITION; EMBRYO; GENE EXPRESSION; GENE MAPPING; HUMAN; HUMAN TISSUE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

RODENTIA; SCHIZOSACCHAROMYCES POMBE;

EID: 0034176694     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.2000.6126     Document Type: Article

References (17)

1. Anderson S. A., Eisenstat D. D., Shi L., Rubenstein J. L. Interneuron migration from basal forebrain to neocortex: Dependence on Dlx genes. Science. 278:1997;474-476.
2. Bulfone A., Gattuso C., Marchitiello A., Pardini C., Boncinelli E., Borsani G., Banfi S., Ballabio A. The embryonic expression pattern of 40 murine cDNAs homologous to Drosophila mutant genes (Dres): A comparative and topographic approach to predict gene function. Hum. Mol. Genet. 7:1998;1997-2006.
3. Ema M., Morita M., Ikawa S., Tanaka M., Matsuda Y., Gotoh O., Saijoh Y., Fujii H., Hamada H., Kikuchi Y., Fujii-Kuriyama Y. Two new members of the murine Sim gene family are transcriptional repressors and show different expression patterns during mouse embryogenesis. Mol. Cell. Biol. 16:1996;5865-5875.
4. Fan C. M., Kuwana E., Bulfone A., Fletcher C. F., Copeland N. G., Jenkins N. A., Crews S., Martinez S., Puelles L., Rubenstein J. L., Tessier-Lavigne M. Expression patterns of two murine homologs of Drosophila single-minded suggest possible roles in embryonic patterning and in the pathogenesis of Down syndrome. Mol. Cell. Neurosci. 7:1996;1-16.
5. Gibbons R. J., Picketts D. J., Villard L., Higgs D. R. Mutations in a putative global transcriptional regulator cause X-linked mental retardation with alpha-thalassemia (ATR-X syndrome). Cell. 80:1995;837-845.
6. Hatten M. E., Heinz N. Neurogenesis and migration. Zigmond M. J., Bloom F. E., Landis S. C., Roberts J. L., Squire L. R. Fundamental Neurosciences. 1999;Academic Press, San Diego.
7. Hogue D. L., Ling V. A human nucleobase transporter-like cDNA (SLC23A1): Member of a transporter family conserved from bacteria to mammals. Genomics. 59:1999;18-23.
8. Hum. Mol. Genet. 7:1998;571-578.
9. Kozak M. Structural features in eukaryotic mRNAs that modulate the initiation of translation. J. Biol. Chem. 266:1991;19867-19870.
10. Lai E. C., Bodner R., Kavaler J., Freschi G., Posakony J. W. Antagonism of Notch signaling activity by members of a novel protein family encoded by the Bearded and Enhancer of split gene complexes. Development. 127:2000;291-306.
11. Lai E. C., Burks C., Posakony J. W. The K box, a conserved 3′ UTR sequence motif, negatively regulates accumulation of enhancer of split complex transcripts. Development. 125:1998;4077-4088.
12. Lai E. C., Posakony J. W. The Bearded box, a novel 3′ UTR sequence motif, mediates negative post-transcriptional regulation of Bearded and Enhancer of split Complex gene expression. Development. 124:1997;4847-4856.
13. Liang P., Pardee A. B. Differential display. A general protocol. Methods Mol. Biol. 85:1997;3-11.
14. Philippe A., Martinez M., Guilloud-Bataille M., Gillberg C., Rastam M., Sponheim E., Coleman M., Zappella M., Aschauer H., van Malldergerme L., Penet C., Feingold J., Brice A., Leboyer M. Genome-wide scan for autism susceptibility genes. Paris Autism Research International Sibpair Study. Hum. Mol. Genet. 8:1999;805-812.
15. Piven J. The biological basis of autism. Curr. Opin. Neurobiol. 7:1997;708-712.
16. Villard L., Gecz J., Mattei J. F., Fontes M., Saugier-Veber P., Munnich A., Lyonnet S. XNP mutation in a large family with Juberg-Marsidi syndrome. Nat. Genet. 12:1996;359-360.
17. Villard L., Lossi A. M., Cardoso C., Proud V., Chiaroni P., Colleaux L., Schwartz C., Fontes M. Determination of the genomic structure of the XNP/ATRX gene encoding a potential zinc finger helicase. Genomics. 43:1997;149-155.