Combining cell culture analogue reactor designs and PBPK models to probe mechanisms of naphthalene toxicity

Biotechnology Progress

Volumn 16, Issue 3, 2000, Pages 334-345

  Ghanem, A ^a,b   Shuler, M L ^a  

^a Department of Population Medicine and Diagnostic Sciences   (United States)

^b The University of Maine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOREACTOR; CELL CULTURE; CELL DEATH; CELL INTERACTION; CYTOTOXICITY; GLUTATHIONE; MAMMAL CELL; MATHEMATICAL MODEL; METABOLITE; NAPHTHALENE; NAPHTHOQUINONE; POLYCYCLIC AROMATIC HYDROCARBON; RAT; REACTOR DESIGN; TOXICITY TESTING;

CELL CULTURE; CELLS; MATHEMATICAL MODELS; METABOLITES; NAPHTHALENE; TISSUE; TOXICITY;

CELL CULTURE ANALOGUE REACTOR; NAPHTHALENE EPOXIDE; PHYSIOLOGICALLY BASED PHARMACOKINETIC MODEL; TOXICOLOGY;

BIOREACTORS;

ANIMALS; BIOREACTORS; CELL CULTURE TECHNIQUES; EQUIPMENT DESIGN; GLUTATHIONE; L-LACTATE DEHYDROGENASE; MOLECULAR PROBES; NAPHTHALENES; PHARMACOKINETICS; RATS; TUMOR CELLS, CULTURED;

ANIMALIA; MAMMALIA;

EID: 0034130030     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp9901522     Document Type: Article

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