A preliminary physiologically based pharmacokinetic model for naphthalene and naphthalene oxide in mice and rats

Annals of Biomedical Engineering

Volumn 24, Issue 2, 1996, Pages 305-320

  Sweeney, Lisa M ^a,c   Shuler, Michael L ^a   Quick, Deborah J ^a   Babish, John G ^b  

^a Cornell University   (United States)

^b Department of Obstetrics Gynecology   (United States)

^c CIIT CENTERS FOR HEALTH RESEARCH   (United States)

Author keywords

Circulating metabolites; Glutathione; Mathematical modeling; PBPK

Indexed keywords

COMPOSITION EFFECTS; LIVING SYSTEMS STUDIES; MATHEMATICAL MODELS; NAPHTHALENE; PHYSIOLOGICAL MODELS; TISSUE;

CIRCULATING METABOLITES; GLUTATHIONE;

PHARMACOKINETICS;

1 NAPHTHOL; ACETYLCYSTEINE DERIVATIVE; ENVIRONMENTAL CHEMICAL; NAPHTHALENE; NAPHTHALENE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; COVALENT BOND; ENANTIOMER; EXCRETION; GLUTATHIONE METABOLISM; MATHEMATICAL MODEL; METABOLITE; MOUSE; NONHUMAN; PHARMACOKINETICS; RAT; TOXICOKINETICS; XENOBIOTIC METABOLISM;

ABSORPTION; ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; BODY FLUID COMPARTMENTS; CELLS, CULTURED; GLUTATHIONE; INJECTIONS, INTRAPERITONEAL; LIVER; LUNG; MICE; MODELS, BIOLOGICAL; NAPHTHALENES; ORGAN SIZE; RATS; REGRESSION ANALYSIS;

EID: 0030111203     PISSN: 00906964     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02667357     Document Type: Article

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