Comparative studies of in vitro inhibition of cytochrome P450 3A4- dependent testosterone 6β-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin

Drug Metabolism and Disposition

Volumn 26, Issue 11, 1998, Pages 1053-1057

  Yamazaki, Hiroshi ^b   Shimada, Tsutomu ^a  

^a OSAKA PREFECTURAL INSTITUTE OF PUBLIC HEALTH   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 INHIBITOR; ERYTHROMYCIN; N NORROXITHROMYCIN; ROXITHROMYCIN; RU 28111; RU 39001; TESTOSTERONE; TROLEANDOMYCIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG SCREENING; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; HUMAN TISSUE; HYDROXYLATION; PRIORITY JOURNAL;

ANTI-BACTERIAL AGENTS; ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INHIBITORS; ERYTHROMYCIN; HUMANS; HYDROXYLATION; METHYLATION; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; RECOMBINANT PROTEINS; ROXITHROMYCIN; STEROID HYDROXYLASES; TROLEANDOMYCIN;

UNIDENTIFIED BACULOVIRUS;

EID: 0031769798     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

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