Promoter-proximal pausing on the hsp70 promoter in Drosophila melanogaster depends on the upstream regulator

Molecular and Cellular Biology

Volumn 20, Issue 7, 2000, Pages 2569-2580

  Tang, Hongbing ^a   Liu, Yingyun ^a   Madabusi, Lakshmi ^a   Gilmour, David S ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; HEAT SHOCK PROTEIN 70; RNA POLYMERASE II;

ANIMAL CELL; ARTICLE; BINDING SITE; DNA FLANKING REGION; DROSOPHILA MELANOGASTER; GENE INDUCTION; HEAT SHOCK; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SALIVARY GLAND; TRANSCRIPTION REGULATION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BASE SEQUENCE; BETA-GALACTOSIDASE; BINDING SITES; DNA FOOTPRINTING; DNA-BINDING PROTEINS; DOSAGE COMPENSATION, GENETIC; DROSOPHILA MELANOGASTER; FEMALE; FUNGAL PROTEINS; GENE EXPRESSION REGULATION; HSP70 HEAT-SHOCK PROTEINS; MALE; MOLECULAR SEQUENCE DATA; MUTATION; PROMOTER REGIONS (GENETICS); REGULATORY SEQUENCES, NUCLEIC ACID; RNA POLYMERASE II; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION FACTORS; X CHROMOSOME; YEASTS;

ANIMALIA; DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 0034117285     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.7.2569-2580.2000     Document Type: Article

References (57)

1. Bello, B., D. Resendez-Perez, and W. J. Gehring. 1998. Spatial and temporal targeting of gene expression in Drosophila by means of a tetracycline-dependent transactivator system. Development 125:2193-2202.
2. Bieschke, E. T., J. C. Wheeler, and J. Tower. 1998. Doxycycline-induced transgene expression during Drosophila development and aging. Mol. Gen. Genet. 258:571-579.
3. Blau, J., H. Xiao, S. McCracken, P. O'Hare, J. Greenblatt, and D. Bentley. 1996. Three functional classes of transcriptional activation domain. Mol. Cell. Biol. 16:2044-2055.
4. Brand, A. H., and N. Perrimon. 1993. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118:401-415.
5. Brown, S. A., A. N. Imbalzano, and R. E. Kingston. 1996. Activator-dependent regulation of transcriptional pausing on nucleosomal templates. Genes Dev. 10:1479-1490.
6. Brown, S. A., C. S. Weirich, E. M. Newton, and R. E. Kingston. 1998. Transcriptional activation domains stimulate initiation and elongation at different times and via different residues. EMBO J. 17:3146-3154.
7. Carey, M., Y.-S. Lin, M. R. Green, and M. Ptashne. 1990. A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives. Nature 345: 361-364.
8. Corton, J. C., E. Moreno, and S. A. Johnston. 1998. Alterations in the GAL4 DNA-binding domain can affect transcriptional activation independent of DNA binding. J. Biol. Chem. 273:13776-13780.
9. Dvir, A., R. C. Conaway, and J. W. Conaway. 1996. Promoter escape by RNA polymerase II. A role for an ATP cofactor in suppression of arrest by polymerase at promoter-proximal sites. J. Biol. Chem. 271:23352-23356.
10. Dvir, A., S. Tan, J. W. Conaway, and R. C. Conaway. 1997. Promoter escape by RNA polymerase II. Formation of an escape-competent transcriptional intermediate is a prerequisite for exit of polymerase from the promoter. J. Biol. Chem. 272:28175-28178.
11. Emanuel, P. A., and D. S. Gilmour. 1993. TFIID recognizes DNA sequences downstream of the TATA element in the hsp 70 heat shock gene. Proc. Natl. Acad. Sci. USA 90:8449-8453.
12. Giardina, C., and J. T. Lis. 1993. DNA melting on yeast RNA polymerase II promoters. Science 261:759-762.
13. Giardina, C., and J. T. Lis. 1995. Dynamic protein-DNA architecture of a yeast heat shock promoter. Mol. Cell. Biol. 15:2737-2744.
14. Giardina, C., M. Perez-Riba, and J. T. Lis. 1992. Promoter melting and TFIID complexes on Drosophila genes in vivo. Genes Dev. 6:2190-2200.
15. Grant, P. A., L. Duggan, J. Cote, S. M. Roberts, J. E. Brownell, R. Candau, R. Ohba, T. Owen-Hughes, C. D. Allis, F. Winston, S. L. Berger, and J. L. Workman. 1997. Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex. Genes Dev. 11:1640-1650.
16. Hiromi, Y., and W. J. Gehring. 1987. Regulation and function of the Drosophila segmentation gene fushi tarazu. Cell 50:963-974.
17. Hoch, M., C. Schroder, E. Seifert, and H. Jackle. 1990. Cis-acting control elements for Krupple expression in the Drosophila embryo. EMBO J. 9: 2587-2595.
18. Katsani, K. R., M. A. Hajibagheri, and C. P. Verrijzer. 1999. Co-operative DNA binding by GAGA transcription factor requires the conserved BTB/ POZ domain and reorganizes promoter topology. EMBO J. 18:698-708.
19. Krumm, A., T. Meulia, M. Brunvand, and M. Groudine. 1992. The block to transcriptional elongation within the human c-myc gene is determined in the promoter-proximal region. Genes Dev. 6:2201-2213.
20. Kumar, K. P., S. Akoulitchev, and D. Reinberg. 1998. Promoter-proximal stalling results from the inability to recruit transcription factor IIH to the transcription complex and is a regulated event. Proc. Natl. Acad. Sci. USA 95:9767-9772.
21. Landick, R. 1997. RNA polymerase slides home: pause and termination site recognition. Cell 88:741-744.
22. Lee, H., K. W. Kraus, M. F. Wolfner, and J. T. Lis. 1992. DNA sequence requirements for generating paused polymerase at the start of hsp70. Genes Dev. 60:284-295.
23. Li, B., J. A. Weber, Y. Chen, A. L. Greenleaf, and D. S. Gilmour. 1996. Analyses of promoter-proximal pausing by RNA polymerase II on the hsp 70 heat shock gene promoter in a Drosophila nuclear extract. Mol. Cell. Biol. 16: 5433-5443.
24. Lis, J. 1998. Promoter-associated pausing in promoter architecture and postinitiation transcriptional regulation. Cold Spring Harbor Symp. Quant. Biol. 63:347-356.
25. Ma, J., and M. Ptashne. 1987. Deletion analysis of GAL4 defines two transcriptional activating segments. Cell 48:847-853.
26. Madabusi, L. V. 1998. Studies on the Drosophila hsp70 core promoter: role of the downstream TFIID contacts in transcription and pausing. Ph.D. thesis. The Pennsylvania State University, University Park, Pa.
27. Marshall, N. F., J. Peng, Z. Xie, and D. H. Price. 1996. Control of RNA polymerase II elongation potential by a novel carboxyl-terminal domain kinase. J. Biol. Chem. 271:27176-27183.
28. Mason, P. B., Jr., and J. T. Lis. 1997. Cooperative and competitive protein interactions at the hsp70 promoter. J. Biol. Chem. 272:33227-33233.
29. Melcher, K., and S. A. Johnston. 1995. GAL4 interacts with TATA-binding protein and coactivators. Mol. Cell. Biol. 15:2839-2848.
30. Mirkovitch, J., and J. E. J. Darnell. 1992. Mapping of RNA polymerase on mammalian genes in cells and nuclei. Mol. Cell. Biol. 3:1085-1094.
31. Mooney, R. A., I. Artsimovitch, and R. Landick. 1998. Information processing by RNA polymerase: recognition of regulatory signals during RNA chain elongation. J. Bacteriol. 180:3265-3275.
32. Moreland, R. J., F. Tirode, Q. Van, J. W. Conaway, J. M. Egly, and R. C. Conaway. 1999. A role for the TFIIH XPB DNA helicase in promoter escape by RNA polymerase II. J. Biol. Chem. 274:22127-22130.
33. O'Brien, T., and J. T. Lis. 1991. RNA polymerase II pauses at the 5′ end of the transcriptionally induced Drosophila hsp70 gene. Mol. Cell. Biol. 11: 5285-5290.
34. Pinaud, S., and J. Mirkovitch. 1998. Regulation of c-fos expression by RNA polymerase elongation competence. J. Mol. Biol. 280:785-798.
35. Purnell, B. A., P. A. Emanuel, and D. S. Gilmour. 1994. TFIID sequence-recognition of the initiator and sequences further downstream in Drosophila class II genes. Genes Dev. 8:830-842.
36. Rasmussen, E. B., and J. T. Lis. 1995. Short transcripts of the ternary complex provide insight into RNA polymerase II elongational pausing. J. Mol. Biol. 252:522-535.
37. Ring, B. Z., and J. W. Roberts. 1994. Function of a nontranscribed DNA strand site in transcription elongation. Cell 78:317-324.
38. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
39. Samkurashvili, I., and D. S. Luse. 1998. Structural changes in the RNA polymerase II transcription complex during transition from initiation to elongation. Mol. Cell. Biol. 18:5343-5354.
40. Serizawa, H., J. W. Conaway, and R. C. Conaway. 1993. Phosphorylation of C-terminal domain of RNA polymerase II is not required in basal transcription. Nature 363:371-374.
41. Shopland, L. S., K. Hirayoshi, M. Fernandes, and J. T. Lis. 1995. HSF access to heat shock elements in vivo depends critically on promoter architecture defined by GAGA factor, TFIID, and RNA polymerase II binding sites. Genes Dev. 9:2756-2769.
42. Simon, J. A., and J. T. Lis. 1987. A germline transformation analysis reveals flexibility in the organization of heat shock consensus elements. Nucleic Acids Res. 15:2971-2988.
43. Spencer, C. A., and M. Groudine. 1990. Transcription elongation and eucaryotic gene regulation. Oncogene 5:777-785.
44. Thummel, C. S., A. M. Boulet, and H. D. Lipshitz. 1988. Vectors for Drosophila P-element-mediated transformation and tissue culture transfection. Gene 74:445-456.
45. Tsukiyama, T., P. B. Becker, and C. Wu. 1994. ATP-dependent nucleosome disruption at a heat-shock promoter mediated by binding of GAGA transcription factor. Nature 367:525-532.
46. Tsukiyama, T., and C. Wu. 1995. Purification and properties of an ATP-dependent nucleosome remodeling factor. Cell 83:1011-1020.
47. Verrijzer, C. P., J. L. Chen, K. Yokomori, and R. Tjian. 1995. Binding of TAFs to core elements directs promoter selectivity by RNA polymerase II. Cell 81:1115-1125.
48. Vincent, J.-P., J. A. Kassis, and P. H. O'Farrell. 1990. A synthetic homeodomain binding site acts as a cell type specific, promoter specific enhancer in Drosophila embryos. EMBO J. 9:2573-2578.
49. Wang, W., M. Carey, and J. D. Gralla. 1992. Polymerase II promoter activation: closed complex formation and ATP-driven start site opening. Science 255:450-453.
50. Weber, J. A., and D. S. Gilmour. 1995. Genomic footprinting of the hsp70 and histone H3 promoters in Drosophila embryos reveal novel protein-DNA interactions. Nucleic Acids Res. 23:3327-3334.
51. Weber, J. A., D. J. Taxman, Q. Lu, and D. S. Gilmour. 1997. Molecular architecture of the hsp70 promoter after deletion of the TATA box or the upstream regulation region. Mol. Cell. Biol. 17:3799-3808.
52. Xiao, H., J. D. Friesen, and J. T. Lis. 1994. A highly conserved domain of RNA polymerase II shares a functional element with acidic activation domains of upstream transcription factors. Mol. Cell. Biol. 14:7507-7516.
53. Yamaguchi, Y., T. Takagi, T. Wada, K. Yano, A. Furuya, S. Sugimoto, J. Hasegawa, and H. Handa. 1999. NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation. Cell 97:41-51.
54. Yankulov, K., and D. Bentley. 1998. Transcriptional control: Tat cofactors and transcriptional elongation. Curr. Biol. 8:R447-R449.
55. Yankulov, K., J. Blau, T. Purton, S. Roberts, and D. L. Bentley. 1994. Transcriptional elongation by RNA polymerase II is stimulated by transactivators. Cell 77:749-759.
56. Zhou, Q., and P. A. Sharp. 1995. Novel mechanism and factor for regulation by HIV-Tat. EMBO J. 14:321-328.
57. Zink, D., and R. Paro. 1995. Drosophila Polycomb-group regulated chromatin inhibits the accessibility of a trans-activator to its target DNA. EMBO J. 14:5660-5671.