Role of water channels in fluid transport studied by phenotype analysis of aquaporin knockout mice

Experimental Physiology

Volumn 85 S, Issue SPEC. ISS., 2000, Pages

  Verkman, A S ^a   Yang, Baoxue ^a   Song, Yuanlin ^a   Manley, Geoffrey T ^a   Ma, Tonghui ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AQUAPORIN;

AIRWAY; ANIMAL EXPERIMENT; BRAIN EDEMA; BRAIN ISCHEMIA; CONTROLLED STUDY; GENE DELETION; KIDNEY CONCENTRATING CAPACITY; LUNG ALVEOLUS EPITHELIUM; LUNG ENDOTHELIUM; MOUSE; NONHUMAN; OSMOSIS; PHENOTYPE; POLYURIA; REVIEW; TRANSGENE; WATER INTOXICATION; WATER PERMEABILITY; WATER TRANSPORT;

EID: 0034103872     PISSN: 09580670     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-445x.2000.tb00028.x     Document Type: Review

References (44)

1. BAI, C. X., FUKUDA, N., SONG, V., MA, T., MATTHAY, M. A. & VERKMAN, A. S. (1999). Role of aquaporin water channels in lung fluid transport. Phenotype analysis of aquaporin 1 and 4 knockout mice. Journal of Clinical Investigation 103, 555-561.
2. BICHET, D. G. (1998). Nephrogenic diabetes insipidus. American Journal of Medicine 47, 1344-1347.
3. CHOU, C. L., KNEPPER, M. A., VAN HOEK, A. N., BROWN, D., MA, T. & VERKMAN, A. W. (1999). Reduced water permeability and altered ultrastructure in thin descending limb of Henle in aquaporin-1 null mice. Journal of Clinical Investigation 103, 491-496.
4. CHOU, C. L., MA, T., YANG, B., KNEPPER, M. A. & VERKMAN, A. S. (1998). Four-fold reduction in water permeability in inner medullary collecting duct of aquuporin-4 knockout mice. American Journal of Physiology 274, C549-554.
5. DEEN, H M., VERKIJK, M. A., KNOERS, N. V., WIERINGA, B., MONNENS, L. A., VAN OS, CH. & VAN COST, B. A. (1994). Requirement of human renal water channel aquaporin-2 for vasopressin-dcpendent concentration of urine. Science 264, 92-95.
6. ECELBARGER, C. A., TERRIS, J., FRINDT, G., ECHKVARRIA, M., MARPLES, D., NIELSEN, S. & KNEPPER, M. A. (1995). Aquaporin-3 water channel localization and regulation in rat kidney. American Journal of Physiology 269, F663-672.
7. FARINAS, J., KNEEN, M., MOORE, M. & VERKMAN, A. S. (1997). Plasma membrane water permeability of cultured cells and epithelia measured by light microscopy with spatial filtering. Journal of General Physiology 110, 283-296.
8. FRIGERI, A., GROPPER, M., TUROK, C. W. & VERKMAN, A. S. (1995a). Immunolocalization of the mercurial-insensitive water channel and glycerol intrinsic protein in epithelial cell plasma membranes. Proceedings of the National Academy of Sciences of the USA 92, 4328-4331.
9. FRIGERI, A., GROPPER, M., UMENISHI, F., KAWASHIMA, M., BROWN, D. & VERKMAN, A. S. (1995b). Localization of MIWC and GLIP water channel homologs in neuromuscular, epithelial and glandular tissues. Journal of Cell Science 108, 2993-3002.
10. MA, T., FUKUDA, N., SONG, V., MATTHAY, M. A. & VERKMAN, A. S. (2000). Lung fluid transport in aquaporin-5 knockout mice. Journal of Clinical Investigation 105, 93-100.
11. MA, T., SONG, Y., GILLESPIE, A., CARLSON, E. J., EPSTEIN, C. J. & VERKMAN, A. S. (1999a). Defective secretion of saliva in transgenic mice lacking aquaporin-5 water channels. Journal of Biological Chemistry 274, 20071-20074.
12. MA, T. & VERKMAN, A. S. (1999). Aquaporin water channels in gastrointestinal physiology. Journal of Physiology 517, 317-326.
13. MA, T., YANG, B., GILLESPIE, A., CARLSON, E. J., EPSTEIN, C. J. & VERKMAN, A. S. (1997). Generation and phenotype of a transgenic knock-out mouse lacking the mercurial-insensitive water channel aquaporin-4. Journal of Clinical Investigation 100, 957-962.
14. MA, T., YANG, B., GILLESPIE, A., CARLSON, E. J., EPSTEIN, C. J. & VERKMAN, A. S. (1998). Severely impaired urinary concentrating ability in transgenic mice lacking aquaporin-1 water channels. Journal of Biological Chemistry 273, 4296-4299.
15. MA, T., YANG, B. & VERKMAN, A. S. (1999b). Targeted gene deletion of aquaporin-3 in mice. Journal of the American Society of Nephrology 10, 19A (abstract).
16. MAEDA, V., SMITH, B. L., AGRE, P., KNEPPER, M. A. (1995). Quantification of aquaporin-CHIP water channel protein in mirodissected renal tubules by fluorescence-based ELISA. Journal of Clinical Investigation 95, 422-428.
17. MANLEY, G. T., FUJIMURA, M., MA, T., FILIZ, F., BOLLEN, A., CHAN, P. & VERKMAN, A. S. (2000). Aquaporin-4 deletion in mice reduces brain edema following acute water intoxication and ischemic stroke. Nature Medicine 6, 159-163.
18. MATTHAY, M. A., FOLKESSON, H. & VERKMAN, A. S. (1996). Salt and water transport across alveolar and distal airway epithelia in the adult lung. American Journal of Physiology 270, L487-503.
19. MOORE, M., MA, T., YANG, B. & VERKMAN, A. S. (2000). Tear secretion by lacrimal glands in mice is not affected by deletion or AQPI, AQP3, AQP4 or AQP5. Experimental Eye Research (in the Press).
20. 2 permeability of Xenopus oocytes. American Journal of Physiology 274, C543-548.
21. NIELSEN, S., FROR, J. & KNEPPER, M. A. (1998). Renal aquaporins. key roles in water balance and water balance disorders. Current Opinion in Nephrology and Hypertension 7, 509-516.
22. OHSHIRO, K., YAOITA, E. & YAMAMOTO, T. (1999). Localization of AQP6 in the intercalated cells of collecting duct in rat kidney. Journal of the American Society of Nephrology 10, 22A (abstract).
23. PALLONE, T. L., EDWAKD, A., MA, T., SILLDORFK, K. & VERKMAN, A. S. (2000). Requirement of aquaporin-1 for NaCl driven water transport across descending vasa recta. Journal of Clinical Investigation 105, 215-222.
24. PRESTON, G. M., SMITH, B. L., ZEIDEL, M. L., MOULDS, J. J. & AGRE, P. (1994). Mutations in aquaporin-1 in phenotypically normal humans without functional CHIP water channels. Science 265, 1585-1587.
25. SCHNERMANN, J., CHOU, C. L., MA, T., TRAYNOR, T., KNEPPER, M. A. & VERKMAN, A. S. (1998). Defective proximal tubular fluid reabsorption in transgenic aquaporin-1 null mice. Proceedings of the National Academy of Sciences of the USA 95, 9660-9664.
26. SONO, Y., MA, T., MATTHAY, M. A. & VERKMAN, A. S. (2000). Role of aquaporin-4 in airspace-to-capillary water permeability in intact mouse lung measured by a novel gravimetric method. Journal of General Physiology 115, 17-27.
27. SPRING, K. R. (1998). Routes and mechanisms of fluid transport by epiihelia. Annual Review of Physiology 60, 105-119.
28. TAMARAPPOO, B. K., KOYAMA, X., GABBERT, M. & VERKMAN, A. S. (1999a). High-throughput screening of combinatorial drug libraries to identify non-mercurial aquaporin inhibitors. Journal of the American Society of Nephrology 10, 25 A (abstract).
29. TAMARAPPOO, B. K., VERKMAN, A. S. (1998). Defective trafficking of AQP2 water channels in Nephrogenic Diabetes Insipidus and correction by chemical chaperones. Journal of Clinical Investigation 101, 2257-226.
30. TAMARAPPOO, B. K., YANG, B. & VERKMAN, A. S. (1999b). Misfolding of mulant aquaporin-2 water channels in nephrogenic diabetes insipidus. Journal of Biological Chemistry 274, 34825-34831.
31. TERRIS, J., ECELBARGER, C. A., MARPLES, D., KNEPPER, M. A., NIELSEN, S. (1995). Distribution of aquaporin-4 water channel expression within rat kidney. American Journal of Physiology 269, F775-785.
32. VAN HOEK, A. N., MA, T., YANG, B., VERKMAN, A. S. & BROWN, D. (2000). Aquaporin-4 is expressed in basolateral membranes of juxtamedullary proximal tubules in mouse kidney. American Journal of Physiology (in the Press).
33. VERBAVATZ, J. M., BHOWN, D., SABOLIC, I., VALENTI, G., AUSIELLO, D. A., VAN HOEK, A. N., MA, T. & VERKMAN, A. S. (1993). Tetrameric assembly of CHIP28 water channels in liposomes and cell membranes. A freeze-fracture study. Journal of Cell Biology 123, 605-618.
34. VERBAVATZ, J. M., MA, T., GOHIN, B. & VERKMAN, A. S. (1997). Absence of orthogonal arrays in kidney, brain and muscle from transgenic knockout mice lacking water channel aquaporin-4. Journal of Cell Science 110, 2855-2860.
35. VERKMAN, A. S. (1999). Lessons on renal physiology from transgenic mice lacking aquaporin water channels. Journal of the American Society of Nephrology 10, 1126-1135.
36. VERKMAN, A. S., MATTHAV, M. A. & SONG, V. (2000). Aquaporin water channels and lung physiology. American Journal of Physiology (in the Press).
37. YAMAMOTO, T. & SAISAKI, S. (1998). Aquaporins in the kidney: emerging new aspects. Kidney International 54, 1041-1051.
38. YANG, B., BROWN, D. & VERKMAN, A. S. (1996). The mercurial-insensitive water channel (AQP-4) forms orthogonal arrays in stably transfected CHO cells. Journal of Biological Chemistry 271, 4577-4580.
39. YANG, B., FOLKENSON, H. G., YANG, J., MATTHAY, M. A., MA, T. & VERKMAN, A. S. (1999). Reduced water permeability of the peritoneal barrier in aquaporin-1 knockout mice. American Journal of Physiology 276, C76-81.
40. YANG, B., FUKUDA, N., VAN HOEK, A. N., MATTHAY, M. A., MA, T. & VERKMAN, A. S. (2000a). Carbon dioxide permeability of aquaporin-1 measured in erythrocytes and lung of aquaporin-1 null mice and in reconstituted proteoliposomes. Journal of Biological Chemistry 275, 2686-2692.
41. YANG, B., MA, T., DONG, J. Y. & VERKMAN, A. S. (20006). Partial correction of the urinary concentrating defect in aquaporin-1 null mice by adenovirus-mediated gene delivery. Human Gene Therapy 11, 567-575.
42. YANG, B., VERBAVATZ, J. M., SONG, Y., VETRIVAL, L., MANLEY, G., KAO, W. M., MA, T. & VERKMAN, A. S. (2000c). Skeletal muscle function and water permeability in aquaporin-4 deficient mice. American Journal of Physiology (in the Press).
43. YANG, B. & VERKMAN, A. S. (1999). A transgenic knock-in mouse model of human nephrogenic diabetes insipidus. Journal of the American Society of Nephrology 10, 26A (abstract).
44. YASUI, M., KWON, T. H., KNEPPER, M. A., NIELSEN, S. & AGRE, P. (1999). Aquaporin 6: an intracellular vesicle water channel protein in renal epithelia. Proceedings of the National Academy of Sciences of the USA 96, 5808-5813.