Role of macrophage scavenger receptors in diet-induced atherosclerosis in mice

Laboratory Investigation

Volumn 78, Issue 4, 1998, Pages 423-434

  Sakaguchi, Hisashi ^a,b   Takeya, Motohiro ^a   Suzuki, Hiroshi ^a,b   Hakamata, Hideki ^a   Kodama, Tatsuhiko ^c   Horiuchi, Seikoh ^a   Gordon, Siamon ^e   Van Der Laan, Luc J W ^f   Kraal, Georg ^f   Ishibashi, Shun ^d   Kitamura, Nobuo ^a   Takahashi, Kiyoshi ^a  

^a KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

^b CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD36 ANTIGEN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; SCAVENGER RECEPTOR; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL CELL; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CHOLESTEROL ESTERIFICATION; CHOLESTEROL METABOLISM; DIETARY INTAKE; GENE EXPRESSION; MACROPHAGE FUNCTION; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ANTIGENS, CD36; ARTERIOSCLEROSIS; DIET; LIPOPROTEINS, VLDL; MACROPHAGES; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; RECEPTORS, IMMUNOLOGIC; RECEPTORS, LDL; RECEPTORS, LIPOPROTEIN; RECEPTORS, SCAVENGER; SCAVENGER RECEPTORS, CLASS B;

EID: 0031958704     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (56)

1. Acton SL, Rigotti A, Landschulz KT, Xu S, Hobbs HH, and Krieger M (1996). Identification of scavenger receptor SR-BI as a high density lipoprotein receptor. Science 271:518-520.
2. Acton SL, Scherer PE, Lodish HF, and Krieger M (1994). Expression cloning of SR-BI, a CD36-related class B scavenger receptor. J Biol Chem 269:21003-21009.
3. Ashkenas J, Penman M, Vasile E, Acton S, Freeman M, and Krieger M (1993). Structures and high and low affinity ligand binding properties of murine type I and type II macrophage scavenger receptors. J Lipid Res 34:983-1000.
4. Brown MS and Goldstein JL (1986). A receptor-mediated pathway for cholesterol homeostasis. Science 232:34-47.
5. Doi T, Kurasawa M, Higashino K, Imanishi T, Mori T, Naito M, Takahashi K, Kawabe Y, Wada Y, Matsumoto A, and Kodama T (1994). The histidine interruption of an alpha-helical coiled coil allosterically mediates a pH-dependent ligand dissociation from macrophage scavenger receptors. J Biol Chem 269:25598-25604.
6. Elomaa O, Kangas M, Sahlberg C, Tuukkanen J, Sormunen R, Liakka A, Thesleff I, Kraal G, and Tryggvason K (1995). Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a subset of macrophages. Cell 80:603-609.
7. Emi M, Asaoka H, Matsumoto A, Itakura H, Kurihara Y, Wada Y, Kanamori H, Yazaki Y, Takahashi E, Lepert M, Lalouel J, Kodama T, and Mukai T (1993). Structure, organization, and chromosomal mapping of the human macrophage scavenger receptor gene. J Biol Chem 268:2120-2125.
8. Endemann G, Stanton LW, Madden KS, Bryant CM, White RT, and Protter AA (1993). CD36 is a receptor for oxidized low density lipoprotein. J Biol Chem 268:11811-11816.
9. Fraser I, Hughes D, and Gordon S (1993). Divalent cation-independent macrophage adhesion inhibited by monoclonal antibody to murine scavenger receptor. Nature 364:343-346.
10. Gåfvels ME, Caird M, Britt D, Jackson CL, Patterson D, and Strauss JF III (1993). Cloning of a cDNA encoding a putative human very low density lipoprotein/apolipoprotein E receptor and assignment of the gene to chromosome 9pter-p23. Somat Cell Mol Genet 19:557-569.
11. Gåfvels ME, Paavola LG, Boyd DO, Nolan PM, Wittmack FM, Chawla A, Lazar MA, Bucan M, Angelin B, and Strauss JF III (1994). Cloning of a complementary deoxyribonucleic acid encoding the murine homologue of the very low density lipoprotein/apolipoprotein-E receptor: Expression pattern and assignment of the gene to mouse chromosome 19. Endocrinology 135:387-394.
12. Gianturco SH, Bradley WA, Gotto AM Jr, Morrisett JD, and Peavy DL (1982). Hypertriglyceridemic very low density lipoproteins induce triglyceride synthesis and accumulation in mouse peritoneal macrophages. J Clin Invest 70:168-178.
13. Goldstein JL, Basu SK, and Brown MS (1983). Receptor-mediated endocytosis of low density lipoprotein in cultured cells. Methods Enzymol 98:241-260.
14. Greenberg ME (1989). Preparation and analysis of RNA. In: Ausubel FM, Brent R, and Kingston RE, editors: Current protocols in molecular biology. New York: John Wiley & Sons, Inc., 4.1-4.5.
15. Herz J and Willnow TE (1994). Functions of the LDL receptor gene family. Ann N Y Acad Sci 737:14-19.
16. Holness CL, da Silva RP, and Fawcett J (1993). Macrosialin, a mouse macrophage-restricted glycoprotein, is a member of the lamp/lgp family. J Biol Chem 268:9661-9666.
17. Ishibashi S, Goldstein JL, Brown MS, Herz J, and Burns DK (1994). Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice. J Clin Invest 93:1885-1893.
18. Isobe S, Nakane PK, and Brown WR (1977). Studies on translocation of immunoglobulins across intestinal epithelium. 1. Improvements to study the peroxidase-labeled antibody for application to study of human intestinal mucosa. Acta Histochem Cytochem 10:161-171.
19. Jokinen EV, Landschultz KT, Wyne KL, Ho YK, Frykman PK, and Hobbs HH (1994). Regulation of the very low density lipoprotein receptor by thyroid hormone in rat skeletal muscle. J Biol Chem 269:26411-26418.
20. Kita T, Yokode M, Watanabe Y, Narumiya S, and Kawai C (1986). Stimulation of cholesteryl ester synthesis in mouse peritoneal macrophage by cholesterol-rich very low density lipoproteins from the Watanabe heritable hyperlipidemic rabbit, an animal model of familial hypercholesterolemia. J Clin Invest 77:1460-1465.
21. Kodama T, Freeman M, Rohrer L, Zabrecky J, Matsudaira P, and Krieger M (1990). Type I macrophage scavenger receptor contains-helical and collagen-like coiled coils. Nature 343: 531-535.
22. Krieger M, Acton S, Ashkenas J, Pearson A, Penman M, and Resnick D (1993). Molecular flypaper, host defense, and atherosclerosis. J Biol Chem 268:4569-4572.
23. Kunijathoor VV, Wilson DL, and LeBoruf RC (1996). Increased atherosclerosis in streptozotocin-induced diabetic mice. J Clin Invest 97:1767-1773.
24. Landschulz KT, Pathak RK, Rigotti A, Krieger M, and Hobbs HH (1996). Regulation of scavenger receptor, class B, type I, a high density lipoprotein receptor, in liver and steroidogenic tissues of the rat. J Clin Invest 98:984-995.
25. Mahley RW (1988). Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology. Science 240:622-630.
26. Marilee L, Lum CM, Ling W, Suzuki H, Kodama T, and Steinbrecher U (1997). High affinity saturable uptake of oxidized low density lipoprotein by macrophagen from mice lacking the scavenger receptor class A type I/II. J Biol Chem 20:12938-12944.
27. Matsumoto A, Naito M, Itakura H, Ikemoto S, Asaoka H, Hayakawa I, Kanamori H, Aburatani H, Takaku F, Suzuki H, Kobari Y, Miyai T, Takahashi K, Cohen EH, Wydro R, Housman DE, and Kodama T (1990). Human macrophage scavenger receptors: Primary structure, expression, and localization in atherosclerotic lesions. Proc Natl Acad Sci U S A 87:9133-9137.
28. Miyazaki A, Rahim AT, Ohta T, Morino Y, and Horiuchi S (1992). High density lipoprotein mediates selective reduction in cholesteryl esters from macrophage foam cells. Biochim Biophys Acta 1126:73-80.
29. Mori T, Takahashi K, Higashi T, Takeya M, Kume S, Kawabe Y, Kodama T, and Horiuchi S (1995). Localization of advanced glycation end products of Maillard reaction in bovine tissues and their endocytosis by macrophage scavenger receptors. Exp Mol Pathol 63:135-152.
30. Mori T, Takahashi K, Naito M, Kodama T, Hakamata H, Sakai M, Miyazaki A, Horiuchi S, and Ando M (1994). Endocytic pathway of scavenger recptors via trans-golgi system in bovine alveolar macrophages. Lab Invest 71:409-416.
31. Multhaupt HAB, Gåfvels ME, Kariko K, Jin H, Arenas-Elliott C, Goldman BI, Strauss JF III, Angelin B, Warhol MJ, and McCrae KR (1996). Expression of very low density lipoprotein receptor in the vascular wall. Am J Pathol 148:1985-1997.
32. Murakami M, Horiuchi S, Takata K, and Morino Y (1987). Distinction in the mode of receptor-mediated endocytosis between high density lipoprotein and acetylated high density lipoprotein: Evidence for high density lipoprotein receptor-mediated cholesterol transfer. J Biochem (Tokyo) 101:729-741.
33. Naito M, Suzuki H, Mori T, Matsumoto A, Kodama T, and Takahashi K (1992). Coexpression of type I and type II human macrophage scavenger receptors in macrophages of various organs and foam cells in atherosclerotic lesions. Am J Pathol 141:591-599.
34. Nakazato K, Ishibashi T, Shindo J, Ahiomi M, and Maruyama Y (1996). Expression of very low density lipoprotein receptor mRNA in rabbit atherosclerotic lesions. Am J Pathol 149: 1831-1838.
35. 2+-catalyzed oxidation of human low density lipoprotein. FEBS Lett 257:435-438.
36. Oka K, Ishimura-Oka K, Chu M-J, Sullivan M, Krushkal J, Li W-H, and Chan L (1994a). Mouse very-low-density-lipoprotein receptor (VLDLR) cDNA cloning, tissue-specific expression and evolutionary relationship with the low-density-lipoprotein receptor. Eur J Biochem 224:975-982.
37. Oka K, Tzung KW, Sullivan M, Lindsay E, Baldini A, and Chan L (1994b). Human very-low-density lipoprotein receptor complementary DNA and deduced amino acid sequence and localization of its gene (VLDLR) to chromosome band 9p24 by fluorescence in situ hybridization. Genomics 20:298-300.
38. Pearson A, Lux A, and Krieger M (1995). Expression cloning of dSR-Cl, a class C macrophage-specific scavenger receptor from Drosophila melanogaster. Proc Natl Acad Sci U S A 92:4056-4060.
39. Plump AS, Smith JD, Hayek T, Aalto-Setala K, Walsh A, Verstuyft JG, Rubin EM, and Breslow JL (1992). Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell 71:343-353.
40. Purcell-Huynh DA (1995). Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet. J Clin Invest 95:2246-2257.
41. Ramprasad MP, Fischer W, Witztum JL, Sambrano GR, Quehenberger O, and Steinberg D (1995). The 94- to 97-kDa mouse macrophage membrane protein that recognizes oxidized low density lipoprotein and phosphatidylserine-rich liposomes is identical to macrosialin, the mouse homologue of human CD68. Proc Natl Acad Sci U S A 92:9580-9584.
42. Rohrer L, Freeman M, Kodama T, Penman M, and Krieger M (1990). Coiled-coil fibrous domains mediate ligand binding by macrophage scavenger receptor type II. Nature 343:570-572.
43. Sakai J, Hoshino A, Takahashi S, Miura Y, Hirofumi I, Kawarabayasi Y, and Yamamoto T (1994). Structure, chromosome location, and expression of the human very low density lipoprotein receptor gene. J Biol Chem 269:2173-2182.
44. Sakai M, Miyazaki A, Hakamata H, Kodama T, Suzuki H, Kobori S, Shichiri M, and Horiuchi S (1996). The scavenger receptor serves as a route for internalization of lysophosphatidylcholine in oxidized low density lipoprotein-induced macrophage proliferation. J Biol Chem 271:27346-27352.
45. Stanton LW, White RT, Bryant CM, Protter AA, and Endemann G (1992). A macrophage Fc receptor for IgG is also a receptor for oxidized low density lipoprotein. J Biol Chem 267:22446-22451.
46. Suzuki H, Kurihara Y, Takeya M, Kamada N, Kataoka M, Jishage K, Ueda O, Sakaguchi H, Higshi T, Suzuki T, Takashima Y, Kawabe Y, Cynshi O, Wada Y, Honda M, Kurihara H, Aburatani H, Doi T, Matsumoto A, Azuma S, Noda T, Toyoda Y, Itakura H, Yazaki Y, Horiuchi S, Takahashi K, Karuijt JK, van Berkel TJC, Steinbrecher UP, Ishibashi S, Maeda N, Gordon S, and Kodama T (1997). A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection. Nature 386:292-296.
47. Tabas I, Myers JN, Innerarity TL, Xu XX, Arnold K, Boyles J, and Maxfield FR (1991). The influence of particle size and multiple apoprotein E-receptor interactions on the endocytic targeting of β-VLDL in mouse peritoneal macrophages. J Biol Chem 115:1547-1560.
48. Takahashi S, Kawarabayasi Y, Nakai T, Sakai J, and Yamamoto T (1992). Rabbit very low density lipoprotein receptor: A low density lipoprotein receptor-like protein with distinct ligand specificity. Proc Natl Acad Sci U S A 89:9252-9256.
49. Tsubamoto Y, Yamada N, Watanabe Y, Inaba T, Shimoi M, Shimano H, Gotoda T, Harada K, Shimada M, Ohsuga J, Kawamura M, and Yazaki Y (1994). Dextran sulfate, a competitive inhibitor for scavenger receptor, prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbits. Atherosclerosis 106:43-50.
50. Umeda S, Takahashi K, Shultz LN, Naito M, and Takagi K (1996). Effects of macrophage colony-stimulating factor on macrophages and their related cell populations in the osteopetrosis mouse defective in production of functional macrophage colony-stimulating factor protein. Am J Pathol 149: 559-574.
51. van der Laan LJW, Kangas M, Döpp EA, Broug-Holub E, Elomaa O, Tryggvason K, and Kraal G (1997). Macrophage scavenger receptor MARCO: In vitro and in vivo regulation and involvement in the anti-bacterial host defense, Immunol Lett 57:203-208.
52. van Lenten BJ, Fogelman AM, Jackson RL, Shapiro S, Haberland ME, and Edwards PA (1985). Receptor-mediated uptake of remnant lipoproteins by cholesterol-loaded human monocyte-macrophages. J Biol Chem 260:8783-8788.
53. Watanabe Y (1980). Serial inbreeding of rabbits with hereditary hyperlipidemia (WHHL-rabbit): Incidence and development of atherosclerosis and xanthoma. Atherosclerosis 36: 261-268.
54. Webb JC, Patel DD, Jones MD, Knight BL, and Soutar AK (1994). Characterization and tissue-specific expression of the human, very low density lipoprotein (VLDL) receptor, mRNA. Hum Mol Genet 3:531-537.
55. Zhang SH, Reddick RL, Burkey B, and Maeda N (1994). Diet-induced atherosclerosis in mice heterozygous and homozygous for apolipoprotein E gene disruption. J Clin Invest 94:937-945.
56. Zhang SH, Reddick RL, Piedrahita JA, and Maeda N (1992). Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science 258:468-471.