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Volumn 5, Issue 2, 2000, Pages 152-161

Communicating genetic risk: Pros, cons, and counsel

Author keywords

BRCA 1; BRCA 2; Breast cancer; Genetic counseling; Ovarian cancer; Psychosocial

Indexed keywords

ADULT; ADVANCED CANCER; ARTICLE; BREAST CANCER; CANCER PATIENT; CANCER RISK; CASE REPORT; FAMILY HISTORY; FEMALE; GENETIC COUNSELING; GENETIC PREDISPOSITION; GENETIC RISK; HUMAN; MEDICAL DECISION MAKING; PRIORITY JOURNAL; PROMOTER REGION; RISK ASSESSMENT; TUMOR SUPPRESSOR GENE;

EID: 0034100312     PISSN: 10837159     EISSN: None     Source Type: Journal    
DOI: 10.1634/theoncologist.5-2-152     Document Type: Article
Times cited : (4)

References (48)
  • 1
    • 0033614998 scopus 로고    scopus 로고
    • Creation of human tumour cells with defined genetic elements
    • Hahn WC, Counter CM, Lundberg AS et al. Creation of human tumour cells with defined genetic elements. Nature 1999;400:464-468.
    • (1999) Nature , vol.400 , pp. 464-468
    • Hahn, W.C.1    Counter, C.M.2    Lundberg, A.S.3
  • 3
    • 0015043748 scopus 로고
    • Mutation and cancer: Statistical study of retinoblastoma
    • Knudson AG Jr. Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci USA 1971;68:820.
    • (1971) Proc Natl Acad Sci USA , vol.68 , pp. 820
    • Knudson A.G., Jr.1
  • 4
    • 0014692015 scopus 로고
    • Suppression of malignancy by cell fusion
    • Harris H, Miller OJ, Klein G et al. Suppression of malignancy by cell fusion. Nature 1969:223:363-368.
    • (1969) Nature , vol.223 , pp. 363-368
    • Harris, H.1    Miller, O.J.2    Klein, G.3
  • 5
    • 0025613812 scopus 로고
    • Linkage of early-onset familial breast cancer to chromosome 17q21
    • Hall JM, Lee MNK, Newman B et al. Linkage of early-onset familial breast cancer to chromosome 17q21. Science 1990:250:1684.
    • (1990) Science , vol.250 , pp. 1684
    • Hall, J.M.1    Lee, M.N.K.2    Newman, B.3
  • 6
    • 0028113345 scopus 로고
    • A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
    • Miki Y, Swensen J, Shattuck-Edens D et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 1994;266:66-71.
    • (1994) Science , vol.266 , pp. 66-71
    • Miki, Y.1    Swensen, J.2    Shattuck-Edens, D.3
  • 7
    • 0006713602 scopus 로고
    • Identification of the breast cancer susceptibility gene BRCA2
    • Wooster R, Bignell G, Lancaster J et al. Identification of the breast cancer susceptibility gene BRCA2. Nature 1995;378:789-792.
    • (1995) Nature , vol.378 , pp. 789-792
    • Wooster, R.1    Bignell, G.2    Lancaster, J.3
  • 8
    • 0033618621 scopus 로고    scopus 로고
    • Association of BRCA1 with the hRad50-hMRe11-p95 complex and the DNA damage response
    • Zhong Q, Chen CF, Li S et al. Association of BRCA1 with the hRad50-hMRe11-p95 complex and the DNA damage response. Science 1999;285:747-750.
    • (1999) Science , vol.285 , pp. 747-750
    • Zhong, Q.1    Chen, C.F.2    Li, S.3
  • 9
    • 0033527717 scopus 로고    scopus 로고
    • Requirement of ATM-dependent phosphorylation of BRCA1 in the DNA damage response to double-strand breaks
    • Cortez D, Wang Y, Qin J et al. Requirement of ATM-dependent phosphorylation of BRCA1 in the DNA damage response to double-strand breaks. Science 1999;286:1162-1166.
    • (1999) Science , vol.286 , pp. 1162-1166
    • Cortez, D.1    Wang, Y.2    Qin, J.3
  • 10
    • 0032703874 scopus 로고    scopus 로고
    • Survival in hereditary breast cancer associated with germline mutations of BRCA2
    • Verhoog LC, Brekelmans CT, Seynaeve C et al. Survival in hereditary breast cancer associated with germline mutations of BRCA2. J Clin Oncol 1999;17:3396-3402.
    • (1999) J Clin Oncol , vol.17 , pp. 3396-3402
    • Verhoog, L.C.1    Brekelmans, C.T.2    Seynaeve, C.3
  • 11
    • 0030910022 scopus 로고    scopus 로고
    • The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews
    • Struewing JP, Hartge P, Wacholder S et al. The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews. N Engl J Med 1997;336:1401-1408.
    • (1997) N Engl J Med , vol.336 , pp. 1401-1408
    • Struewing, J.P.1    Hartge, P.2    Wacholder, S.3
  • 12
    • 0031972611 scopus 로고    scopus 로고
    • Current perspectives on radiation-induced breast cancer
    • Gross PE, Sierra S. Current perspectives on radiation-induced breast cancer. J Clin Oncol 1998;16:338-347.
    • (1998) J Clin Oncol , vol.16 , pp. 338-347
    • Gross, P.E.1    Sierra, S.2
  • 13
    • 0009121723 scopus 로고    scopus 로고
    • Mammography: An individual's estimated risk that the examination itself will cause radiation-induced breast cancer
    • San Francisco: Committee for Nuclear Responsibility, Inc. C.N.R. Book Division
    • Gofman JW. Mammography: an individual's estimated risk that the examination itself will cause radiation-induced breast cancer. In: Preventing Breast Cancer: The Story of a Major, Proven. Preventable Cause of This Disease. Second Edition. San Francisco: Committee for Nuclear Responsibility, Inc. C.N.R. Book Division, 1996:172-181.
    • (1996) Preventing Breast Cancer: The Story of a Major, Proven. Preventable Cause of This Disease. Second Edition , pp. 172-181
    • Gofman, J.W.1
  • 14
    • 85038047662 scopus 로고    scopus 로고
    • BRCA1/2 status, family history and ipsilateral breast tumor relapse following conservative surgery and radiation therapy
    • Smith TE, Harrold EV, Matloff ET et al. BRCA1/2 status, family history and ipsilateral breast tumor relapse following conservative surgery and radiation therapy. Proc Am Soc Clin Oncol 1999:2413a.
    • (1999) Proc Am Soc Clin Oncol
    • Smith, T.E.1    Harrold, E.V.2    Matloff, E.T.3
  • 15
    • 1642609543 scopus 로고    scopus 로고
    • Is breast conservation appropriate for women with hereditary breast cancer?
    • Simmonds P, Eccles D, Goddard J et al. Is breast conservation appropriate for women with hereditary breast cancer? Proc Am Soc Clin Oncol 1999;18:2363a.
    • (1999) Proc Am Soc Clin Oncol , vol.18
    • Simmonds, P.1    Eccles, D.2    Goddard, J.3
  • 16
    • 0032887486 scopus 로고    scopus 로고
    • BRCA1/BRCA2 germline mutations in locally recurrent breast cancer patients after lumpectomy and radiation therapy: Implications for breast-conserving management in patients with BRCA1/BRCA2 mutations
    • Turner BC, Harrold E, Matloff E et al. BRCA1/BRCA2 germline mutations in locally recurrent breast cancer patients after lumpectomy and radiation therapy: implications for breast-conserving management in patients with BRCA1/BRCA2 mutations. J Clin Oncol 1999;10:3017-3024.
    • (1999) J Clin Oncol , vol.10 , pp. 3017-3024
    • Turner, B.C.1    Harrold, E.2    Matloff, E.3
  • 17
    • 0033975147 scopus 로고    scopus 로고
    • Genetic predisposition to breast cancer: A surgical perspective
    • Sakorafas GH, Tsiotuo AG. Genetic predisposition to breast cancer: a surgical perspective. Br J Surg 2000;87:149-162.
    • (2000) Br J Surg , vol.87 , pp. 149-162
    • Sakorafas, G.H.1    Tsiotuo, A.G.2
  • 18
    • 0031755914 scopus 로고    scopus 로고
    • Frequency of germline and somatic BRCA1 mutations in ovarian cancer
    • Berchuck A, Heron KA, Carney ME et al. Frequency of germline and somatic BRCA1 mutations in ovarian cancer. Clin Cancer Res 1998;4:2433-2437.
    • (1998) Clin Cancer Res , vol.4 , pp. 2433-2437
    • Berchuck, A.1    Heron, K.A.2    Carney, M.E.3
  • 19
    • 85038044827 scopus 로고    scopus 로고
    • BRCA1 promoter hypermethylation: A mechanism of gene inactivation in sporadic ovarian carcinoma
    • Abstract 27
    • Baldwin RL, Trang HT, Elizabeta N et al. BRCA1 promoter hypermethylation: a mechanism of gene inactivation in sporadic ovarian carcinoma. Prog Soc Gynecol Oncol 2000:Abstract 27.
    • (2000) Prog Soc Gynecol Oncol
    • Baldwin, R.L.1    Trang, H.T.2    Elizabeta, N.3
  • 20
    • 0027467494 scopus 로고
    • Extracolonic cancer in hereditary nonpolyposis colorectal cancer
    • Watson P, Lynch HT. Extracolonic cancer in hereditary nonpolyposis colorectal cancer. Cancer 1993;71:677-685.
    • (1993) Cancer , vol.71 , pp. 677-685
    • Watson, P.1    Lynch, H.T.2
  • 21
    • 0030049823 scopus 로고    scopus 로고
    • BRCA1 mutations in a population-based sample of young women with breast cancer
    • Langston AA, Malone KE, Thompson JD et al. BRCA1 mutations in a population-based sample of young women with breast cancer. N Engl J Med 1996;334:137-142.
    • (1996) N Engl J Med , vol.334 , pp. 137-142
    • Langston, A.A.1    Malone, K.E.2    Thompson, J.D.3
  • 22
    • 13344260688 scopus 로고    scopus 로고
    • Germ-line BRCA1 mutations in Jewish and non-Jewish women with early-onset breast cancer
    • Fitzgerald MG, MacDonald DJ, Krainer M et al. Germ-line BRCA1 mutations in Jewish and non-Jewish women with early-onset breast cancer. N Engl J Med 1996;334:143-149.
    • (1996) N Engl J Med , vol.334 , pp. 143-149
    • Fitzgerald, M.G.1    MacDonald, D.J.2    Krainer, M.3
  • 23
    • 2642695719 scopus 로고    scopus 로고
    • BRCA1 related breast cancer in Austrian breast and ovarian cancer families: Specific BRCA1 mutations and pathological characteristics
    • Wagner TM, Moslinger RA, Muhr D et al. BRCA1 related breast cancer in Austrian breast and ovarian cancer families: specific BRCA1 mutations and pathological characteristics. Int J Cancer 1998;77:354-360.
    • (1998) Int J Cancer , vol.77 , pp. 354-360
    • Wagner, T.M.1    Moslinger, R.A.2    Muhr, D.3
  • 24
    • 0343918505 scopus 로고    scopus 로고
    • BRCA1 mutations in women attending clinics that evaluate the risk of breast cancer
    • Couch FJ, Deshano ML, Blackwood MA et al. BRCA1 mutations in women attending clinics that evaluate the risk of breast cancer. N Engl J Med 1997;336:1409-1415.
    • (1997) N Engl J Med , vol.336 , pp. 1409-1415
    • Couch, F.J.1    Deshano, M.L.2    Blackwood, M.A.3
  • 25
    • 0031029633 scopus 로고    scopus 로고
    • Probability of carrying a mutation of breast-ovarian cancer gene BRCA1 based on family history
    • Berry DA, Parmigiani G, Sanchez J et al. Probability of carrying a mutation of breast-ovarian cancer gene BRCA1 based on family history. J Natl Cancer Inst 1997:89:227-238.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 227-238
    • Berry, D.A.1    Parmigiani, G.2    Sanchez, J.3
  • 26
    • 0031917403 scopus 로고    scopus 로고
    • Determining carrier probabilites for breast cancer susceptibility genes BRCA1 and BRCA2
    • Parmigiani G, Berry DA, Aguilar O. Determining carrier probabilites for breast cancer susceptibility genes BRCA1 and BRCA2. Am J Hum Genet 1998;62:145-158.
    • (1998) Am J Hum Genet , vol.62 , pp. 145-158
    • Parmigiani, G.1    Berry, D.A.2    Aguilar, O.3
  • 27
    • 0034002175 scopus 로고    scopus 로고
    • Single-strand conformation polymorphism analysis by capillary and microchip electrophoresis: A fast, simple method for detection of common mutations in BRCA1 and BRCA2
    • Tian H, Jaquins-Gerstl A, Munro N et al. Single-strand conformation polymorphism analysis by capillary and microchip electrophoresis: a fast, simple method for detection of common mutations in BRCA1 and BRCA2. Genomics 2000;63:25-34.
    • (2000) Genomics , vol.63 , pp. 25-34
    • Tian, H.1    Jaquins-Gerstl, A.2    Munro, N.3
  • 28
    • 0031753049 scopus 로고    scopus 로고
    • Awareness and attitudes concerning BRCA gene testing
    • Mogilner A, Otten M, Cunningham JD et al. Awareness and attitudes concerning BRCA gene testing. Ann Surg Oncol 1998;5:607-612.
    • (1998) Ann Surg Oncol , vol.5 , pp. 607-612
    • Mogilner, A.1    Otten, M.2    Cunningham, J.D.3
  • 29
    • 0030866838 scopus 로고    scopus 로고
    • Predisposition genetic testing for late-onset disorders in adults: A position paper of the National Society of Genetic Counselors
    • McKinnon WC, Baty BJ, Bennett RL et al. Predisposition genetic testing for late-onset disorders in adults: a position paper of the National Society of Genetic Counselors. JAMA 1997;278:1217-1220.
    • (1997) JAMA , vol.278 , pp. 1217-1220
    • McKinnon, W.C.1    Baty, B.J.2    Bennett, R.L.3
  • 30
    • 0032703873 scopus 로고    scopus 로고
    • Breast cancer in carriers of BRCA1 and BRCA2 mutations: Tackling a molecular and clinical conundrum
    • Haber DA. Breast cancer in carriers of BRCA1 and BRCA2 mutations: tackling a molecular and clinical conundrum. J Clin Oncol 1999;17:3367-3370.
    • (1999) J Clin Oncol , vol.17 , pp. 3367-3370
    • Haber, D.A.1
  • 31
    • 0031291674 scopus 로고    scopus 로고
    • Genetic counseling for BRCA1/BRCA2 testing
    • Schneider KA. Genetic counseling for BRCA1/BRCA2 testing. Genetic Testing 1997;1:91-98.
    • (1997) Genetic Testing , vol.1 , pp. 91-98
    • Schneider, K.A.1
  • 32
    • 0030939329 scopus 로고    scopus 로고
    • Genetic testing for susceptibility to adult-onset cancer: The process and content of informed consent
    • Geller G, Botkin JR, Green MJ et al. Genetic testing for susceptibility to adult-onset cancer: the process and content of informed consent. JAMA 1997;277:1467-1473.
    • (1997) JAMA , vol.277 , pp. 1467-1473
    • Geller, G.1    Botkin, J.R.2    Green, M.J.3
  • 33
    • 0030963119 scopus 로고    scopus 로고
    • Am Soc Clin Oncol Special Article: Recommended breast cancer surveillance guidelines
    • Am Soc Clin Oncol Special Article: Recommended breast cancer surveillance guidelines. J Clin Oncol 1997;15:2149-2156.
    • (1997) J Clin Oncol , vol.15 , pp. 2149-2156
  • 34
    • 19244362641 scopus 로고    scopus 로고
    • Adverse psychological events occurring in the first year after predictive testing for Huntington's disease. The Canadian collaborative study predictive testing
    • Lawson K, Wiggins S, Green T et al. Adverse psychological events occurring in the first year after predictive testing for Huntington's disease. The Canadian collaborative study predictive testing. J Med Genet 1996;33:856-862.
    • (1996) J Med Genet , vol.33 , pp. 856-862
    • Lawson, K.1    Wiggins, S.2    Green, T.3
  • 35
    • 0025184187 scopus 로고
    • Psychological outcomes of different treatment policies in women with early breast cancer outside a clinical trial
    • Fallowfield LJ, Hall A, Maguire GP et al. Psychological outcomes of different treatment policies in women with early breast cancer outside a clinical trial. Br Med J 1990;301:575-580.
    • (1990) Br Med J , vol.301 , pp. 575-580
    • Fallowfield, L.J.1    Hall, A.2    Maguire, G.P.3
  • 36
    • 0029886710 scopus 로고    scopus 로고
    • Anxiety in women "at risk" of developing breast cancer
    • Thirlaway K, Fallowfield L, Nunnerley H et al. Anxiety in women "at risk" of developing breast cancer. Br J Cancer 1996;73:1422-1424.
    • (1996) Br J Cancer , vol.73 , pp. 1422-1424
    • Thirlaway, K.1    Fallowfield, L.2    Nunnerley, H.3
  • 37
    • 0014665574 scopus 로고
    • Gaps in doctor-patient communication
    • Francis V, Korsch B, Morris M. Gaps in doctor-patient communication. N Engl J Med 1969;280:535-538.
    • (1969) N Engl J Med , vol.280 , pp. 535-538
    • Francis, V.1    Korsch, B.2    Morris, M.3
  • 38
    • 0034716620 scopus 로고    scopus 로고
    • Qualitative study of interpretation of reassurance among patients attending rheumatology clinics: "just a touch of arthritis, doctor?"
    • Donovan JL, Blake DR. Qualitative study of interpretation of reassurance among patients attending rheumatology clinics: "just a touch of arthritis, doctor?" Br Med J 2000;320:541-544.
    • (2000) Br Med J , vol.320 , pp. 541-544
    • Donovan, J.L.1    Blake, D.R.2
  • 39
    • 0030893779 scopus 로고    scopus 로고
    • Recommendations for follow-up care of individuals with inherited predisposition to cancer. II. BRCA1 and BRCA2. Cancer Genetics Studies Consortium
    • Burke W, Daly M, Garber J et al. Recommendations for follow-up care of individuals with inherited predisposition to cancer. II. BRCA1 and BRCA2. Cancer Genetics Studies Consortium. JAMA. 1997;277:997-1003.
    • (1997) JAMA. , vol.277 , pp. 997-1003
    • Burke, W.1    Daly, M.2    Garber, J.3
  • 40
    • 0027365739 scopus 로고
    • Report of the International Workshop on Screening for Breast Cancer
    • Fletcher SW, Black W, Harris R et al. Report of the International Workshop on Screening for Breast Cancer. J Natl Cancer Inst 1993;85:1644-1656.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 1644-1656
    • Fletcher, S.W.1    Black, W.2    Harris, R.3
  • 41
    • 0033611962 scopus 로고    scopus 로고
    • Screening mammography under age 50
    • Antman K, Shea S. Screening mammography under age 50. JAMA 1999;281:1470-1472.
    • (1999) JAMA , vol.281 , pp. 1470-1472
    • Antman, K.1    Shea, S.2
  • 42
    • 17144461981 scopus 로고    scopus 로고
    • Confusion about breast cancer screening
    • Fletcher SW. Confusion about breast cancer screening [Letter]. N Engl J Med 1997;337:1850.
    • (1997) N Engl J Med , vol.337 , pp. 1850
    • Fletcher, S.W.1
  • 43
    • 0028801693 scopus 로고
    • Ovarian cancer: Screening, treatment, and follow-up
    • NIH Consensus Conference. Ovarian cancer: screening, treatment, and follow-up. JAMA 1995;273:491-497.
    • (1995) JAMA , vol.273 , pp. 491-497
  • 44
    • 0033541548 scopus 로고    scopus 로고
    • Screening for ovarian cancer: A pilot randomised controlled trial
    • Jacobs IJ, Skates SJ, MacDonald N et al. Screening for ovarian cancer: a pilot randomised controlled trial. Lancet 1999;353:1207-1210.
    • (1999) Lancet , vol.353 , pp. 1207-1210
    • Jacobs, I.J.1    Skates, S.J.2    MacDonald, N.3
  • 45
    • 0030909527 scopus 로고    scopus 로고
    • Decision analysis: Effects of prophylactic mastectomy and oophorectomy on life expectancy among women with BRCA1 and BRCA2 mutations
    • Schrag D, Kuntz KM, Garber JE et al. Decision analysis: effects of prophylactic mastectomy and oophorectomy on life expectancy among women with BRCA1 and BRCA2 mutations. N Engl J Med 1997;336:1465-1471.
    • (1997) N Engl J Med , vol.336 , pp. 1465-1471
    • Schrag, D.1    Kuntz, K.M.2    Garber, J.E.3
  • 46
    • 0032537990 scopus 로고    scopus 로고
    • Tamoxifen for prevention of breast cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 study
    • Fisher B, Constantino JP, Wickerham DL et al. Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 study. J Natl Cancer Inst 1998;90:1371-1388.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1371-1388
    • Fisher, B.1    Constantino, J.P.2    Wickerham, D.L.3
  • 47
    • 0033575083 scopus 로고    scopus 로고
    • The effect of raloxifene on risk of breast cancer in postmenopausal women: Results from the MORE randomized trial - Multiple Outcomes of Raloxifene Evaluation
    • Cummings SR, Eckert S, Krueger KA et al. The effect of raloxifene on risk of breast cancer in postmenopausal women: results from the MORE randomized trial - Multiple Outcomes of Raloxifene Evaluation. JAMA 1999;281:2189-2197.
    • (1999) JAMA , vol.281 , pp. 2189-2197
    • Cummings, S.R.1    Eckert, S.2    Krueger, K.A.3


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