메뉴 건너뛰기




Volumn 33, Issue 1, 2000, Pages 1-6

Minor immunophilin binding of tacrolimus and sirolimus metabolites

Author keywords

Cross reactivity; Immunophilin; Metabolite; Radioreceptor assay; Sirolimus; Tacrolimus

Indexed keywords

DRUG METABOLITE; IMMUNOPHILIN; PROTEIN SUBUNIT; RAPAMYCIN; TACROLIMUS;

EID: 0034099456     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-9120(99)00080-6     Document Type: Article
Times cited : (9)

References (22)
  • 1
    • 0025647885 scopus 로고
    • Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 and rapamycin
    • Bierer B.E., Mattila P.S., Standaert R.F., et al. Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 and rapamycin. Proc Natl Acta Sci USA. 87:1990;9231-9235.
    • (1990) Proc Natl Acta Sci USA , vol.87 , pp. 9231-9235
    • Bierer, B.E.1    Mattila, P.S.2    Standaert, R.F.3
  • 2
    • 0025022365 scopus 로고
    • Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK506 and rapamycin
    • Dumont F.J., Saruch M.J., Koprak S.L., Melino M.R., Sigal N.H. Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK506 and rapamycin. J Immunol. 144:(1):1990;1418-1424.
    • (1990) J Immunol , vol.144 , Issue.1 , pp. 1418-1424
    • Dumont, F.J.1    Saruch, M.J.2    Koprak, S.L.3    Melino, M.R.4    Sigal, N.H.5
  • 3
    • 0026969189 scopus 로고
    • Rapamycin inhibits the phosphorylation of p70 S6 kinase in IL-2 and mitogen-activated human T cells
    • Terada N., Lucas J.J., Szepesi A., Franklin R.A., Takase K., Gelfand E.W. Rapamycin inhibits the phosphorylation of p70 S6 kinase in IL-2 and mitogen-activated human T cells. Biochem Biophys Res Commun. 186:(3):1992;1315-1321.
    • (1992) Biochem Biophys Res Commun , vol.186 , Issue.3 , pp. 1315-1321
    • Terada, N.1    Lucas, J.J.2    Szepesi, A.3    Franklin, R.A.4    Takase, K.5    Gelfand, E.W.6
  • 4
    • 0343958393 scopus 로고
    • Pharmacokinetics of FK506 in transplantation patients
    • Venkataramanan R, Jain A, Warty VS, et al. Pharmacokinetics of FK506 in transplantation patients. Transplant Proc 1990; 22(1, Suppl 1): 60-3.
    • (1990) Transplant Proc , vol.22 , Issue.1 SUPPL 1 , pp. 60-63
    • Venkataramanan, R.1    Jain, A.2    Warty, V.S.3
  • 5
    • 0026089524 scopus 로고
    • Pharmacokinetics of FK506 following oral administration: A comparison of FK506 and cyclosporine
    • Venkataramanan R., Jain A., Warty V.S., et al. Pharmacokinetics of FK506 following oral administration a comparison of FK506 and cyclosporine . Transplant Proc. 23:(1):1991;931-933.
    • (1991) Transplant Proc , vol.23 , Issue.1 , pp. 931-933
    • Venkataramanan, R.1    Jain, A.2    Warty, V.S.3
  • 6
    • 0028812794 scopus 로고
    • Potential applications of therapeutic drug monitoring of sirolimus immunosuppression in clinical renal transplantation
    • Kahan B.D., Murgia M.G., Slaton J., Napoli K. Potential applications of therapeutic drug monitoring of sirolimus immunosuppression in clinical renal transplantation. Ther Drug Monit. 17:(6):1995;672-675.
    • (1995) Ther Drug Monit , vol.17 , Issue.6 , pp. 672-675
    • Kahan, B.D.1    Murgia, M.G.2    Slaton, J.3    Napoli, K.4
  • 7
    • 0027945930 scopus 로고
    • Measurement of blood concentration of FK506 (tacrolimus) and its metabolites in seven liver graft patients after the first dose the HPLC-MS and microparticle enzyme immunoassay (MEIA)
    • Gonschior A., Christians U., Braun F., et al. Measurement of blood concentration of FK506 (tacrolimus) and its metabolites in seven liver graft patients after the first dose the HPLC-MS and microparticle enzyme immunoassay (MEIA). Br J Clin Pharamocol. 38:1994;567-571.
    • (1994) Br J Clin Pharamocol , vol.38 , pp. 567-571
    • Gonschior, A.1    Christians, U.2    Braun, F.3
  • 8
    • 0028810418 scopus 로고
    • Consensus document: Therapeutic monitoring of tacrolimus (FK506)
    • Jusko W.J., Thomson A.W., Fung J., et al. Consensus document therapeutic monitoring of tacrolimus (FK506) . Ther Drug Monit. 17:1995;606-614.
    • (1995) Ther Drug Monit , vol.17 , pp. 606-614
    • Jusko, W.J.1    Thomson, A.W.2    Fung, J.3
  • 9
    • 0028824489 scopus 로고
    • Lake Louise Consensus conference on cyclosporin monitoring in organ transplantation: Report of the consensus panel
    • Oellerich V., Armstrong V.W., Kahan B., et al. Lake Louise Consensus conference on cyclosporin monitoring in organ transplantation report of the consensus panel . Ther Drug Monit. 17:1995;642-654.
    • (1995) Ther Drug Monit , vol.17 , pp. 642-654
    • Oellerich, V.1    Armstrong, V.W.2    Kahan, B.3
  • 10
    • 0028852056 scopus 로고
    • Consensus guidelines for therapeutic drug monitoring of rapamycin: Report of the consensus panel
    • Yatscoff R.W., Boeckx R., Holt D.W., et al. Consensus guidelines for therapeutic drug monitoring of rapamycin report of the consensus panel . Ther Drug Monit. 17:1995;676-680.
    • (1995) Ther Drug Monit , vol.17 , pp. 676-680
    • Yatscoff, R.W.1    Boeckx, R.2    Holt, D.W.3
  • 11
    • 0032420378 scopus 로고    scopus 로고
    • Tacrolimus metabolite cross-reactivity in different tacrolimus assays
    • Murthy J.N., Davis D.L., Yatscoff R., Soldin S.J. Tacrolimus metabolite cross-reactivity in different tacrolimus assays. Clin Biochem. 31:(8):1998;613-617.
    • (1998) Clin Biochem , vol.31 , Issue.8 , pp. 613-617
    • Murthy, J.N.1    Davis, D.L.2    Yatscoff, R.3    Soldin, S.J.4
  • 13
    • 0030940628 scopus 로고    scopus 로고
    • Identification of a 37 kDa tacrolimus, sirolimus and cyclosporine binding immunophilin possessing glyceraldehyde-3-phosphate dehydrogenase activity from Jurkat T cell line
    • Murthy J.N., Goodyear N., Soldin S.J. Identification of a 37 kDa tacrolimus, sirolimus and cyclosporine binding immunophilin possessing glyceraldehyde-3-phosphate dehydrogenase activity from Jurkat T cell line. Clin Biochem. 30:1997;129-133.
    • (1997) Clin Biochem , vol.30 , pp. 129-133
    • Murthy, J.N.1    Goodyear, N.2    Soldin, S.J.3
  • 15
    • 0026519765 scopus 로고
    • Isolation of two immunosuppressive metabolites after in vitro metabolism of rapamycin
    • Christians U., Sattler M., Schiebel H.M., et al. Isolation of two immunosuppressive metabolites after in vitro metabolism of rapamycin. Drug Metab Dispos. 20:1992;186-191.
    • (1992) Drug Metab Dispos , vol.20 , pp. 186-191
    • Christians, U.1    Sattler, M.2    Schiebel, H.M.3
  • 16
    • 0028500440 scopus 로고
    • High performance liquid chromatographic isolation, spectroscopic characterization and immunosuppressive activities of two rapamycin degradation products
    • Wang C.P., Chan K.W., Schiksinis R.A., Scantina J.A., Sisenwine S.F. High performance liquid chromatographic isolation, spectroscopic characterization and immunosuppressive activities of two rapamycin degradation products. J Liq Chromatogr. 17:1994;3383-3392.
    • (1994) J Liq Chromatogr , vol.17 , pp. 3383-3392
    • Wang, C.P.1    Chan, K.W.2    Schiksinis, R.A.3    Scantina, J.A.4    Sisenwine, S.F.5
  • 17
    • 0029126123 scopus 로고
    • High performance liquid chromatographic isolation, spectroscopic characterization and immunosuppressive activities of three major metabolites from the plasma of rats receiving rapamycin (sirolimus) orally
    • Wang C.P., Lim H.K., Chan K.W., Schiksinis R.A., Scantina J.A., Sisenwine S.F. High performance liquid chromatographic isolation, spectroscopic characterization and immunosuppressive activities of three major metabolites from the plasma of rats receiving rapamycin (sirolimus) orally. J Liq Chromatogr. 18:1995;2559-2568.
    • (1995) J Liq Chromatogr , vol.18 , pp. 2559-2568
    • Wang, C.P.1    Lim, H.K.2    Chan, K.W.3    Schiksinis, R.A.4    Scantina, J.A.5    Sisenwine, S.F.6
  • 18
    • 0028792553 scopus 로고
    • Analysis of tacrolimus (FK506) in relation to therapeutic drug monitoring
    • Jusko W.J. Analysis of tacrolimus (FK506) in relation to therapeutic drug monitoring. Ther Drug Monit. 17:1995;596-601.
    • (1995) Ther Drug Monit , vol.17 , pp. 596-601
    • Jusko, W.J.1
  • 19
  • 20
    • 0029738491 scopus 로고    scopus 로고
    • Sensitive and specific quantitation of sirolimus (rapamycin) and its metabolites in blood of kidney graft recipients by HPLC/electrospray-mass spectrometry
    • Streit F., Christians U., Schiebel H.M., et al. Sensitive and specific quantitation of sirolimus (rapamycin) and its metabolites in blood of kidney graft recipients by HPLC/electrospray-mass spectrometry. Clin Chem. 42:1996;1417-1425.
    • (1996) Clin Chem , vol.42 , pp. 1417-1425
    • Streit, F.1    Christians, U.2    Schiebel, H.M.3
  • 21
    • 0032128447 scopus 로고    scopus 로고
    • Rapamycin: Distribution, pharmacokinetics and therapeutic range investigations: An update
    • Trepanier D.J., Gallant H., Legatt D.F., Yatscoff R.W. Rapamycin distribution, pharmacokinetics and therapeutic range investigations: an update . Clin Biochem. 31:(5):1998;345-351.
    • (1998) Clin Biochem , vol.31 , Issue.5 , pp. 345-351
    • Trepanier, D.J.1    Gallant, H.2    Legatt, D.F.3    Yatscoff, R.W.4
  • 22
    • 0029783338 scopus 로고    scopus 로고
    • Tacrolimus (FK506) metabolite patterns in blood from liver and kidney transplant patients
    • Gonschior A.K., Christians U., Winkler M., Linck A., Baumann J., Sewing F.K. Tacrolimus (FK506) metabolite patterns in blood from liver and kidney transplant patients. Clin Chem. 42:1996;1426-1432.
    • (1996) Clin Chem , vol.42 , pp. 1426-1432
    • Gonschior, A.K.1    Christians, U.2    Winkler, M.3    Linck, A.4    Baumann, J.5    Sewing, F.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.