Structural basis for the biological activity of dendrotoxin-I, a potent potassium channel blocker

Biopolymers

Volumn 54, Issue 1, 2000, Pages 44-57

  Katoh, Etsuko ^a   Nishio, Hideki ^b   Inui, Tatsuya ^b   Nishiuchi, Yuji ^b   Kimura, Terutoshi ^b   Sakakibara, Shumpei ^b   Yamazaki, Toshimasa ^a  

^a NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES   (Japan)

^b Protein Research Foundation   (Japan)

Author keywords

Dendrotoxin; Molecular model for biological activity; nmr spectroscopy; Potassium channel; Potassium channel blocker; Protein structure

Indexed keywords

AMINO ACIDS; ELECTRIC POTENTIAL; MATHEMATICAL MODELS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POTASSIUM;

DENDROTOXIN; POTASSIUM CHANNEL BLOCKER;

PROTEINS;

DENDROTOXIN; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; SNAKE VENOM;

ARTICLE; CRYSTAL STRUCTURE; DRUG DESIGN; MOLECULAR MODEL; NONHUMAN; PROTEIN DOMAIN; PROTEIN TERTIARY STRUCTURE; STRUCTURE ACTIVITY RELATION; TOXIN STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; APROTININ; BRAIN CHEMISTRY; ELAPID VENOMS; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDES; POTASSIUM CHANNEL BLOCKERS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; SYNAPTOSOMES;

EID: 0034096955     PISSN: 00063525     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0282(200007)54:1<44::AID-BIP50>3.0.CO;2-Z     Document Type: Article

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