Identification of three separate binding sites on SHK toxin, a potent inhibitor of voltage-dependent potassium channels in human T-lymphocytes and rat brain

Biochemical and Biophysical Research Communications

Volumn 219, Issue 3, 1996, Pages 696-701

  Pennington, M W ^a   Mahnir, V M ^b   Krafte, D S ^c   Zaydenberg, I ^a   Byrnes, M E ^a   Khaytin, I ^a   Crowley, K ^c   Kem, W R ^b  

^a Bachem Holding AG   (Switzerland)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; SEA ANEMONE TOXIN; SYNTHETIC PEPTIDE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; BRAIN; CIRCULAR DICHROISM; CONTROLLED STUDY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; RAT; STRUCTURE ACTIVITY RELATION; T LYMPHOCYTE; TOXIN STRUCTURE;

EID: 0029997350     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.1996.0297     Document Type: Article

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