Structure-permeability relationships for transcorneal penetration

Alternatives to Laboratory Animals

Volumn 28, Issue 3, 2000, Pages 403-413

  Worth, Andrew P ^a,b   Cronin, Mark T D ^b  

^a JOINT RESEARCH CENTRE   (Italy)

^b LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

Author keywords

Membrane penetration; Ocular drug; Rabbit cornea; Structure permeability relationship

Indexed keywords

DRUG;

ANIMAL TISSUE; ARTICLE; DRUG DELIVERY SYSTEM; DRUG PENETRATION; LIPOPHILICITY; MEMBRANE PERMEABILITY; NONHUMAN; PRIORITY JOURNAL; RABBIT; STRUCTURE ACTIVITY RELATION;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0034094140     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119290002800318     Document Type: Article

References (16)

1. Goskonda, V.R., Khan, M.A., Hutak, C.M. & Reddy, I.K. (1999). Permeability characteristics of novel mydriatic agents using an in vitro culture model that utilizes SIRC rabbit corneal cells. Journal of Pharmaceutical Sciences 88, 180-184.
2. Yoshida, F. & Topliss, J.G. (1996). Unified model for the corneal permeability of related and diverse compounds with respect to their physicochemical properties. Journal of Pharmaceutical Sciences 85, 819-823.
3. Cronin, M.T.D., Dearden, J.C., Gupta, R. & Moss, G.P. (1998). An investigation of the mechanism of flux across polydimethylsiloxane membranes by use of quantitative structure-permeability relationships. Journal of Pharmacy and Pharmacology 50, 143-152.
4. Potts, R.O. & Guy, R.H. (1992). Predicting skin permeability. Pharmaceutical Research 9, 663-669.
5. Cronin, M.T.D., Dearden, J.C., Moss, G.P. & Murray-Dickson, G. (1999). Investigation of the mechanism of flux across human skin in vitro by quantitative structure-permeability relationships. European Journal of Pharmaceutical Sciences 7, 325-330.
6. Prausnitz, M.R. & Noonan, J.S. (1998). Permeability of cornea, sciera and conjunctiva: a literature analysis for drug delivery to the eye. Journal of Pharmaceutical Sciences 87, 1479-1488.
7. Hamalainen, K.M., Kontturi, K., Auriola, S., Murtomaki, L. & Urtti, A. (1997). Estimation of pore size and pore density of biomembranes from permeability measurements of polyethylene glycols using an effusion-like approach. Journal of Controlled Release 49, 97-104.
8. Kawazu, K., Yamada, K., Nakamura, M. & Ota, A. (1999). Characterization of cyclosporin A transport in cultured rabbit corneal epithelial cells: P-glycoprotein transport activity and binding to cyclophilin. Investigative Ophthalmology and Visual Science 40, 1738-1744.
9. Dewar, M.J.S., Zoebisch, E.G., Healy, E.F. & Stewart, J.J.P. (1985). The development and use of quantum-mechanical models. 76. AM1: a new general-purpose quantum-mechanical molecular model. Journal of the American Chemical Society 107, 3902-3909.
10. Sasaki, H., Ichikawa, M., Yamamura, K., Nishida, K. & Nakamura, J. (1997). Ocular membrane permeability of hydrophilic drugs for ocular peptide delivery. Journal of Pharmacy and Pharmacology 49, 135-139.
11. Igarashi, H., Sato, Y., Hamada, S. & Kawasaki, I. (1984). Studies on rabbit corneal permeability of local anesthetics I. Japanese Journal of Pharmacology 34, 429-434.
12. Takahashi, H., Kaminski, A.E. & Zieske, J.D. (1996). Glucose transporter 1 expression is enhanced during corneal epithelial wound repair. Experimental Eye Research 63, 649-659.
13. Schoenwald, R.D. & Ward, R.L. (1978). Relationship between steroid permeability across excised rabbit cornea and octanol-water partition coefficients. Journal of Pharmaceutical Sciences 67, 786-788.
14. Topliss, J.G. & Costello, R.J. (1972). Chance correlations in structure-activity studies using multiple regression analysis. Journal of Medicinal Chemistry 15, 1066-1068.
15. Kang, F., Kuang, K., Li, J. & Fischbarg, J. (1999). Cultured bovine corneal epithelial cells express a functional aquaporin water channel. Investigative Ophthalmology and Visual Science 40, 253-257.
16. Hamalainen, K.M., Kananen, K., Auriola, S., Kontturi, K. & Urtti, A. (1997). Characterization of paracellular and aqueous penetration routes in cornea, conjunctiva and sciera. Investigative Ophthalmology and Visual Science 38, 627-624.