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Volumn 6, Issue 4, 2000, Pages 385-386

Caspase cleavage of APP results in a cytotoxic proteolytic peptide

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CASPASE; GENE PRODUCT;

EID: 0034088719     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/74644     Document Type: Short Survey
Times cited : (20)

References (13)
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    • Caspase structure, proteolytic substrates and function during apoptotic cell death
    • Nicholson, D.W. Caspase structure, proteolytic substrates and function during apoptotic cell death. Cell Death and Diff. 6, 1028-1042 (1999).
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  • 7
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    • Increased production of amyloid precursor protein provides a substrate for caspase-3 in dying motoneurons
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  • 8
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    • Yankner, B.A., Duffy, L.K. & Kirschner, D.A. Neurotrophic and neurotoxic effects of Amyloid b protein: Reversal by Tachykinin neuropeptides. Science 250, 279-282 (1990).
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    • Yankner, B.A.1    Duffy, L.K.2    Kirschner, D.A.3
  • 9
    • 0033600274 scopus 로고    scopus 로고
    • Translating cell biology into therapeutic advances in Alzheimer's disease
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    • Selkoe, D.J.1
  • 10
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    • Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease
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    • Alternative, non-secretase processing of Alzheimer's beta-amyloid precursor protein during apoptosis by caspase-6 and -8
    • Pellegrini, L., Passer, B.J., Tabaton, M., Ganjei, J.K. & D'Adamio L. Alternative, non-secretase processing of Alzheimer's beta-amyloid precursor protein during apoptosis by caspase-6 and -8. J. Biol. Chem. 274, 21011-21016 (1999).
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.