Estrogen mediates the sex difference in post-burn immunosuppression

Journal of Endocrinology

Volumn 164, Issue 2, 2000, Pages 129-138

  Gregory, M S ^a   Duffner, L A ^a   Faunce, D E ^a   Kovacs, E J ^a,b  

^a LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

^b Burn and Shock Trauma Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; ESTROGEN; INTERLEUKIN 6;

ANIMAL MODEL; ARTICLE; BURN; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; ESTROGEN ACTIVITY; FEMALE; HORMONE ACTION; IMMUNE SYSTEM; IMMUNOREGULATION; MACROPHAGE; MALE; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; THERMAL INJURY;

EID: 0034087646     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1640129     Document Type: Article

References (64)

1. Akira S, Hirano T, Taga T & Kishimoto T 1990 Biology and multifunctional cytokines: IL 6 and related molecules (IL 1 and TNF). FASEB Journal 4 2860-2867.
2. Angele MK, Wichmann MW, Ayala A, Cioffi WG & Chaudry IH 1997 Testosterone receptor blockade after hemorrhage in males. Archives of Surgery 132 1207-1214.
3. Ansar-Ahmed S, Penhale WJ & Talal N 1985 Sex hormones, immune responses and autoimmune disease. American Journal of Pathology 121 531-551.
4. Bankey, PE, Williams JG, Guice KS & Taylor SN 1995 lnterleukin-6 production after thermal injury: evidence for non-macrophage sources in the lung and liver. Surgery 118 431-139.
5. Chang WC 1989 Effects of estradiol on prostaglandin E2 biosynthesis and prostaglandin metabolic enzyme activity in rat kidneys. Advances in Prostaglandin, Thromboxane, and Leukotriene Research 19 225-228.
6. Chao, TC, Van Alten PJ, Greager JA &Walters RJ 1995 Steroid sex hormones regulate the release of tumor necrosis factor by macrophages. Cellular Immunology 160 43-49.
7. Christeff TN, Benasssayag C, Carli-Vielle C, Carli A & Nunez EA 1988 Elevated oestrogen and reduced testosterone levels in the serum of male septic shock patients. Journal of Steroid Biochemistry 29 435-440.
8. Christeff N, Carli A, Benasssayag C, Bleichner G, Vaxelaire JF & Nunez EA 1992 Relationship between changes in serum estrone levels and outcome in human males with septic shock. Circulatory Shock 36 249-255.
9. Cutolo M, Sulli A, Seriolo B, Accardo S & Msai A 1995 Estrogens, the immune response and autoimmunity. Clinical and Experimental Rheumatology 13 217-260.
10. De M & Wood GW 1990 Influence ot oestrogen and progesterone on macrophage distribution in the mouse uterus. Journal of Endocrinology 126 417-424.
11. De M, Sanford TR & Wood GW 1992 lnterleukin-1, interleukin-6, and tumor necrosis factor alpha are produced in the mouse uterus during the estrous cycle and are induced by estrogen and progesterone. Developmental Biology 151 297-305.
12. Demelia L, Carruxi R, Vallenbona E, Sauna G, Pitzuz F & Solinas A 1987 Adrenal sex steroid hormones in postnecrotic liver cirrhosis. In Liver and Hormones, pp 249-254. Eds A Francavilla, C Panella, A De Leo & DH Van Theil. Raven Press: Serno Symposia Publications.
13. Denizot F & Lang R 1986 Rapid colorimetric assay for cell growth and survival: modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. Journal of Immunological Methods 89 271-277.
14. Depshpande R, Khalili H, Pergolizzi RG, Michael SD & Chang MY 1997 Estradiol down-regulates LPS-induced cytokine production and NFΚB activation in murine macrophages. American Journal of Reproductive Immunology 38 46-54.
15. Dolecek R 1985 Endocrine response after burns. Journal of Bum Care and Rehabilitation 6 381-394.
16. Dolecek R 1989 Endocrine changes after burn injury. Keio Journal of Medicine 38 262-276.
17. Drost AG, Brelson DG, Cioffi WG, Jordan BS, Mason AD & Pruitt BA 1993 Plasma cytokines following thermal injury and their relationship with patient mortality, burn size, and time post bum. Journal of Trauma 35 335-339.
18. Du JT, Venoos E, Ramey E & Ramwell PW 1984 Sex differences in arachidonate cyclo-oxygenase products in elicited rat peritoneal macrophages. Biochemica et Biophysica Acta 794 256-260.
19. Faist E, Mewes A, Stradder T, Alkan S, Baker G, Ertel W & Heberer G 1988 Alterations of monocyte function following major trauma. Archives of Surgery 123 287-292.
20. Faist E, Schinkel C & Zimmer S 1996 Update on the mechanisms of immune suppression of injury and immune modulation. World Journal of Surgery 20 454-459.
21. Faunce DE, Gregory MS & Kovacs EJ 1997 Effects of acute ethanol exposure on cellular immune responses in a murine model of thermal injury. Journal of Leukocyte Biology 62 733-740.
22. Faunce DE, Gregory MS & Kovacs EJ 1998 Acute ethanol exposure prior to thermal injury results in decreased T cell responses mediated in part by increased production of IL-6. Shock 10 135-140.
23. Finn R, Hill CA, Govan AJ, Ralfs IG & Gurney FG, 1972 Imniunological responsiveness in pregnancy and survival of fetal homograft. British Medical Journal 3 150-152.
24. Fourrier F, Jallot A, Leclerc L, Jourdain M, Racadot A, Chagnon J-L, Rime A & Chopin C 1994 Sex steroid hormones in circulatory shock sepsis syndrome and septic shock. Circulatory Shock 43 171-178.
25. Frazier-Jessen MR & Kovacs EJ 1995 Estrogen modulation of JE/MCP-1 mRNA expression in macrophages. Journal of Immunology 154 1838-1845.
26. Fukushima R, Alexander JW. Wu JZ, Mao JX, Szczur K, Stephens AM, Ogle JD & Ogle CK 1994 Time course of production of cytokine and prostaglandin E2 macrophages isolated after thermal injury and bacterial translocation. Circulatory Shock 42 154-162.
27. Gennari R, Alexander JW, Pyles T, Hartman S & Ogle CK 1994 Effects of antimurine interleukin-6 on bacterial translocation during gut-derived sepsis. Archives of Surgery 129 1191-1197.
28. Grossman CJ 1984 Regulation of the immune system by sex steroids. Endocrine Reviews 5 435-445.
29. Grossman CJ 1991 Immunoendocrinology. In Basic and Clinical Endocrinology, edn 3, pp 40-52, Ed FS Greenspan. Connecticut: Appleton and Lang.
30. Hu SH, Mitcho YL & Rath NC 1988 Effects of estradiol on IL-1 synthesis by macrophages. Journal of Immunopharmacology 10 247-252.
31. Klaiber EL, Brovermann DM, Haffajee CL, Hochmann JS, Sacks GL & Dalen JE 1982 Serum estrogen levels in men with acute myocardial infarction. American Journal of Medicine 73 872-881.
32. Kley, HK, Keck E & Kruskemper HL 1976 Estrone and estradiol inpatients with cirrhosis of the liver: effects of ACTH and dexamethasone. Journal of Clinical Endocrinology and Metabolism 43 557-560.
33. Kopf M, Baumann H, Freer G, Freudenberg M, Lamers M, Kishimoto T, Zinkernagel R, Bluethmann H & Kohler G 1994 Impaired immune and acute-phase responses in interleukin-6-deficient mice. Nature 368 339-342.
34. Kuckerman SH, Ahmari SE, Bryan-Poole N, Evans GF, Short L & Glasebrook AL 1996 Estriol: a potent regulator of TNF and IL-6 expression in a murine model of endotoxemia. Inflammation 20 581-597.
35. Lephart ED, Baxter CR & Parker CR 1987 Effect of burn trauma on adrenal and testicular steroid production. Journal of Clinical Endocrinology and Metabolism 64 842-848.
36. Li AG, Danis VA & Brooks PM 1993 Effect of gonadal steroids on the production of IL-1 and IL-6 by blood mononuclear cells in vitro. Clinical and Experimental Rheumatology 11 157-162.
37. Lieberman ME, Maurer RA, Claude P, Wiklund J, Wertz N & Gorski J 1981 Regulation of pituitary growth and prolactin gene expression by estrogen. Advances in Experimental Medicine and Biology 138 151-163.
38. Liu Z, Simpson RJ & Cheers C 1994 Role of IL-6 in activation of T cells for acquired cellular resistance to Listeria monocytogenes. Journal of Immunology 152 5375-5380.
39. Miller CL & Baker CC 1979 Changes in lymphocyte activity after thermal injury, Journal of Clinical Investigation 63 202-210.
40. Miller L & Hunt JS 1996 Sex steroid hormones and macrophage function. Life Sciences 59 1-14.
41. Ogle CK, Mao JX, Wu JZ, Ogle JD & Alexander JW 1994 The production of tumor necrosis factor, interleukin-1, interleukin-6, and prostaglandin E2 by isolated enterocytes and gut macrophages: effect of lipopolysaccharide and thermal injury. Journal of Burn Care and Rehabilitation 15 470-477.
42. Paavonen T 1994 Hormonal regulation of immune responses. Annals of Medicine 26 255-258.
43. Paavonen T, Andersson LC & Aldercreutz H 1981 Sex hormone regulation of in vitro immune response: estradiol enhances human B cell maturation via inhibition of suppressor T cells in pokeweed mitogen stimulated cultures. Journal of Experimental Medicine 154 1935-1945.
44. Plymate SR, Vaughan GM, Mason AD & Pruitt BA 1987 Central hypogonadism in burned men. Hormone Research 27 152-158.
45. Purtillo DT, Hallgren HM & Yunis EJ 1972 Depressed maternal lymphocyte response to PHA in human pregnancy. Lancet 754 769-771.
46. Schluter B, Konig B, Bergmann U, Muller FE & Konig W 1991 Interleukin-6 - a potential mediator of lethal sepsis after major thermal trauma: evidence for increased IL-6 production by peripheral blood mononuclear cells. Journal of Trauma 31 1663-1670.
47. Schuurs AHWM & Verhuel HAM 1990 Effects of gender and sex steroids on the immune response. Journal of Steroid Biochemistry 35 157-172.
48. Shupnik MA 1996 Gonadal hormone feedback on pituitary gonadotropin genes. Trends in Endocrine Metabolism 7 272-276.
49. Simpson ER, Ackerman GE, Smit ME & Mendelson CR 1981 Estrogen formation in stromal cells of adipose tissue in women: induction by glucocorticoids. Proceedings of the National Academy of Sciences of the USA 9 5690-5694.
50. Starnes HF, Pearce MK, Tewari A, Yim JH, Zou JC & Abrams JS 1990 Anti-IL-6 monoclonal antibodies protect against lethal Eschericia coli and lethal tumor necrosis factor-a challenge in mice. Journal of Immunology 145 4185-4191.
51. Stein B & Yang MX 1995 Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-ΚB and C/EBPβ. Journal of Molecular and Cellular Biology 15 4971-4979.
52. Thong YH, Steele RW, Vincent MM, Hensen SA & Bellanti JA 1973 Impaired in vitro cell-mediated immunity to rubella virus during pregnancy. New England Journal of Medicine 289 604-606.
53. Ueyama M, Maruyama I, Osame M & Sawada Y 1992 Marked increases in plasma interleukin-6 in burn patients. Journal of Laboratory and Clinical Medicine b 693-698.
54. Waage A, Brandtzaeg P, Halstensen A, Kierulf P & Espevik T 1989 The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between IL-6, IL-1, and fatal outcome. Journal of Experimental Medicine 169 333-338.
55. Walker HL & Mason AD 1968 A standard animal burn. Journal of Trauma 8 1049-1051.
56. Weinstein Y, Ran S & Segal S 1984 Sex-associated differences in the regulation of immune response controlled by the MHC of the mouse. Journal of Immunology 132 656-661.
57. Welshons WV, Wolf MF, Murphy CS & Jordan VC 1988 Estrogenic activity of phenol red. Molecular and Cellular Endocrinology 57 169-178.
58. Weusten JJ, Blankenstein MA, Gmelig-Meyling FH, Scuurman HJ, Kater L & Thijssen JH 1986 Presence of estrogen receptors in human blood mononuclear cells and thymocytes. Acta Endocrinologica 112 409-415.
59. Wichmann MW, Zellweger R, DeMaso CM, Ayala A & Chaudry IH 1996 Enhanced immune responses in females, as opposed to decreased responses in males following hemorrhagic shock and resuscitation. Cytokine 88 853-863.
60. Wood JJ, Grbic JT, Roderick ML, Jordan A & Mannick JA 1987 Suppression of interleukin-2 production in an animal model of thermal injury is related to prostaglandin synthesis. Archives of Surgery 122 179-184.
61. Woolf PD, Hamill RW, McDonald JV, Lee LA & Kelly M 1985 Transient hypogonadotropic hypogonadism caused by critical illness. Journal of Clinical Endocrinology and Metabolism 60 444-450.
62. Zellweger R, Wichmann MW, Ayala A, Stein S, DeMaso CM & Chaudry IH 1997 Females in proestrus state maintain splenic immune functions and tolerate sepsis better than males. Critical Care Medicine 25 106-110.
63. Zhou D, Munster A & Winchurch RA 1991 Pathologic concentrations of interleukin 6 inhibit T cell responses via induction of activation of TGF-beta. FASEB Journal 5 2582-2585.
64. Zhou D, Muntser AM & Winchurch RA 1992 Inhibitory effect of interleukin 6 on immunity: possible implications in burn patients. Archives of Surgery 127 65-69.