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Volumn 3, Issue 1, 1998, Pages 15-20

Transcription factor NF-κB: Friend or foe of neurons?

Author keywords

Alzheimer's disease; Neurodegeneration; Neuroprotection; NF B; Oxidative stress; Transcription factors

Indexed keywords

ANTIOXIDANT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NEUROTOXIN; REACTIVE OXYGEN METABOLITE;

EID: 0031962438     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4000295     Document Type: Review
Times cited : (61)

References (78)
  • 1
    • 0024520513 scopus 로고
    • Central nervous sytem trauma and stroke. I. Biochemical considerations for oxygen radical formation and lipid peroxidation
    • Hall ED, Braughler JM. Central nervous sytem trauma and stroke. I. Biochemical considerations for oxygen radical formation and lipid peroxidation. Free Radic Biol Med 1989; 6: 289-301.
    • (1989) Free Radic Biol Med , vol.6 , pp. 289-301
    • Hall, E.D.1    Braughler, J.M.2
  • 2
    • 0024589421 scopus 로고
    • Central nervous system trauma and stroke. II. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation
    • Hall ED, Braughler JM. Central nervous system trauma and stroke. II. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation. Free Radic Biol Med 1989; 6: 303-313.
    • (1989) Free Radic Biol Med , vol.6 , pp. 303-313
    • Hall, E.D.1    Braughler, J.M.2
  • 3
    • 0026754574 scopus 로고
    • Reactive oxygen species and the central nervous system
    • Halliwell B. Reactive oxygen species and the central nervous system. J Neurochem 1932; 59: 1609-1623.
    • (1932) J Neurochem , vol.59 , pp. 1609-1623
    • Halliwell, B.1
  • 4
    • 0028762647 scopus 로고
    • Excitatory amino acids as a final common pathway for neurologic disorders
    • Lipton SA, Rosenberg PA. Excitatory amino acids as a final common pathway for neurologic disorders. N Engl J Med 1994; 330: 613-622.
    • (1994) N Engl J Med , vol.330 , pp. 613-622
    • Lipton, S.A.1    Rosenberg, P.A.2
  • 5
    • 0027171266 scopus 로고
    • Oxidants, antioxidants, and the degenerative diseases of aging
    • Ames BN, Shigenaga MK, Hagen TM. Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci USA 1993; 90: 7915-7922.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7915-7922
    • Ames, B.N.1    Shigenaga, M.K.2    Hagen, T.M.3
  • 6
    • 0027496238 scopus 로고
    • A radical hypothesis for neurodegeneration
    • Olanow CW. A radical hypothesis for neurodegeneration. Trends Neurosci 1993; 16: 439-444.
    • (1993) Trends Neurosci , vol.16 , pp. 439-444
    • Olanow, C.W.1
  • 8
    • 0026636441 scopus 로고
    • Free radicals, antioxidants and human diseases: Where are we now?
    • Halliwell B, Gutteridge JMC, Cross CE. Free radicals, antioxidants and human diseases: where are we now? J Lab Clin Med 1992; 119: 598-620.
    • (1992) J Lab Clin Med , vol.119 , pp. 598-620
    • Halliwell, B.1    Gutteridge, J.M.C.2    Cross, C.E.3
  • 10
    • 0028793087 scopus 로고
    • Functional pleiotropy of the neurohormone melatonin: Antioxidant protection and neuroendocrine regulation
    • Reiter RJ. Functional pleiotropy of the neurohormone melatonin: antioxidant protection and neuroendocrine regulation. Front Neuroendocrinol 1995; 16: 383-415.
    • (1995) Front Neuroendocrinol , vol.16 , pp. 383-415
    • Reiter, R.J.1
  • 11
    • 0029028294 scopus 로고
    • An in vitro EPR study of the free radical scavenging actions of the lazaroids antioxidants U-74500A and U-7851F
    • Zhao W, Richardson JS, Mombourquette MJ, Weil JA. An in vitro EPR study of the free radical scavenging actions of the lazaroids antioxidants U-74500A and U-7851F. Free Radic Biol Med 1995; 19: 21-30.
    • (1995) Free Radic Biol Med , vol.19 , pp. 21-30
    • Zhao, W.1    Richardson, J.S.2    Mombourquette, M.J.3    Weil, J.A.4
  • 12
    • 0029804987 scopus 로고    scopus 로고
    • Melatonin prevents oxidative stress-induced cell death in hippocampal cells
    • Lezoualc'h F, Skutella T, Widmann M, Behl C. Melatonin prevents oxidative stress-induced cell death in hippocampal cells. Neuroreport 1996; 7: 2071-2077.
    • (1996) Neuroreport , vol.7 , pp. 2071-2077
    • Lezoualc'h, F.1    Skutella, T.2    Widmann, M.3    Behl, C.4
  • 13
    • 0027269781 scopus 로고
    • 2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor
    • 2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor. EMBO J 1993; 12: 2005-2015.
    • (1993) EMBO J , vol.12 , pp. 2005-2015
    • Meyer, M.1    Schreck, R.2    Baeuerle, P.A.3
  • 14
    • 0028466383 scopus 로고
    • Oxygen and the control of gene expression
    • Pahl HL, Baeuerle PA. Oxygen and the control of gene expression. Bioessays 1994; 16: 497-502.
    • (1994) Bioessays , vol.16 , pp. 497-502
    • Pahl, H.L.1    Baeuerle, P.A.2
  • 15
    • 0025739254 scopus 로고
    • Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-κB transcription factor and HIV-1
    • Schreck R, Rieber P, Baeuerle PA. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-κB transcription factor and HIV-1. EMBO J 1991; 10: 2247-2258.
    • (1991) EMBO J , vol.10 , pp. 2247-2258
    • Schreck, R.1    Rieber, P.2    Baeuerle, P.A.3
  • 16
    • 0022481133 scopus 로고
    • Multiple nuclear factors interact with the immunoglobulin enhancer sequences
    • Sen R, Baltimore D. Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell 1986; 46: 705-716.
    • (1986) Cell , vol.46 , pp. 705-716
    • Sen, R.1    Baltimore, D.2
  • 17
    • 0027232067 scopus 로고
    • NF-κB and Rel: Participants in a multiform transcriptional regulatory system
    • Grilli M, Chiu JJ, Lenardo MJ. NF-κB and Rel: participants in a multiform transcriptional regulatory system. Int Rev Cytol 1993; 143: 1-62.
    • (1993) Int Rev Cytol , vol.143 , pp. 1-62
    • Grilli, M.1    Chiu, J.J.2    Lenardo, M.J.3
  • 18
    • 0028174061 scopus 로고
    • Function and activation of NF-κB in the immune system
    • Baeuerle P, Henkel T. Function and activation of NF-κB in the immune system. Annu Rev Immunol 1994; 12: 141-179.
    • (1994) Annu Rev Immunol , vol.12 , pp. 141-179
    • Baeuerle, P.1    Henkel, T.2
  • 19
    • 0029874138 scopus 로고    scopus 로고
    • The NF-κB and IκB proteins: New discoveries and insights
    • Baldwin AS. The NF-κB and IκB proteins: new discoveries and insights. Annu Rev Immunol 1996; 14: 649-683.
    • (1996) Annu Rev Immunol , vol.14 , pp. 649-683
    • Baldwin, A.S.1
  • 20
    • 0025865317 scopus 로고
    • The inducible transcription activator NF-κB: Regulation by distinct protein subunits
    • Baeuerle PA. The inducible transcription activator NF-κB: regulation by distinct protein subunits. Biochem Biophys Acta 1991; 1072: 63-80.
    • (1991) Biochem Biophys Acta , vol.1072 , pp. 63-80
    • Baeuerle, P.A.1
  • 22
    • 0030271387 scopus 로고    scopus 로고
    • NF-κB: Ten years after
    • Baeuerle P, Baltimore D, NF-κB: ten years after. Cell 1996; 87: 13-20.
    • (1996) Cell , vol.87 , pp. 13-20
    • Baeuerle, P.1    Baltimore, D.2
  • 24
    • 0023724778 scopus 로고
    • IκB: A specific inhibitor of the NF-κB transcription factor
    • Baeuerle P, Baltimore D. IκB: a specific inhibitor of the NF-κB transcription factor. Science 1988; 242: 540-546.
    • (1988) Science , vol.242 , pp. 540-546
    • Baeuerle, P.1    Baltimore, D.2
  • 25
    • 0026590966 scopus 로고
    • IκBγ, a 70 kd protein identical to the C-terminal half of p110 NF-κB: A new member of the IκB family
    • Inoue J, Kerr LD, Kakizuka A, Verma IM. IκBγ, a 70 kd protein identical to the C-terminal half of p110 NF-κB: a new member of the IκB family. Cell 1992; 68: 1109-1120.
    • (1992) Cell , vol.68 , pp. 1109-1120
    • Inoue, J.1    Kerr, L.D.2    Kakizuka, A.3    Verma, I.M.4
  • 26
    • 0027165587 scopus 로고
    • Common structural constituents confer IκB activity to NF-κB p105 and IκB/MAD-3
    • Hatada EN, Naumann M, Scheidereit C. Common structural constituents confer IκB activity to NF-κB p105 and IκB/MAD-3. EMBO J 1993; 12: 2781-2788.
    • (1993) EMBO J , vol.12 , pp. 2781-2788
    • Hatada, E.N.1    Naumann, M.2    Scheidereit, C.3
  • 27
    • 0027332498 scopus 로고
    • The IκB proteins: Multifunctional regulators of Rel/NF-κB transcription factors
    • Beg AA, Baldwin AS Jr. The IκB proteins: multifunctional regulators of Rel/NF-κB transcription factors. Genes Dev 1993; 7: 2064-2070.
    • (1993) Genes Dev , vol.7 , pp. 2064-2070
    • Beg, A.A.1    Baldwin Jr., A.S.2
  • 28
    • 0027400286 scopus 로고
    • Nuclear uptake control of NF-κB by MAD-3, an I kappa B protein present in the nucleus
    • Zabel U, Henkel T, Silva MS, Baeuerle PA. Nuclear uptake control of NF-κB by MAD-3, an I kappa B protein present in the nucleus. EMBO J 1993; 12: 201-211.
    • (1993) EMBO J , vol.12 , pp. 201-211
    • Zabel, U.1    Henkel, T.2    Silva, M.S.3    Baeuerle, P.A.4
  • 30
    • 0023818885 scopus 로고
    • Alzheimer's disease: Its proteins and genes
    • Glenner GG. Alzheimer's disease: its proteins and genes. Cell 1988; 52: 307-308.
    • (1988) Cell , vol.52 , pp. 307-308
    • Glenner, G.G.1
  • 31
    • 0028233494 scopus 로고
    • Hydrogen peroxide mediates amyloid β protein toxicity
    • Behl C, Davis JB, Lesley R, Schubert D. Hydrogen peroxide mediates amyloid β protein toxicity. Cell 1994; 77: 817-827.
    • (1994) Cell , vol.77 , pp. 817-827
    • Behl, C.1    Davis, J.B.2    Lesley, R.3    Schubert, D.4
  • 32
    • 0024990330 scopus 로고
    • Neurotrophic and neurotoxic effects of amyloid β protein: Reversal by tachykinin neuropeptides
    • Yankner BA, Duffy LK, Kirschner DA. Neurotrophic and neurotoxic effects of amyloid β protein: reversal by tachykinin neuropeptides. Science 1990; 250: 279-282.
    • (1990) Science , vol.250 , pp. 279-282
    • Yankner, B.A.1    Duffy, L.K.2    Kirschner, D.A.3
  • 34
    • 0025110182 scopus 로고
    • β amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage
    • Koh JY, Yan LL, Cotman CW. β amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage. Brain Res 1990; 533: 315-320.
    • (1990) Brain Res , vol.533 , pp. 315-320
    • Koh, J.Y.1    Yan, L.L.2    Cotman, C.W.3
  • 35
    • 0026570528 scopus 로고
    • β-amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
    • Mattson MP, Cheng B, Davis D, Bryant K, Lieberburg I, Rydel R. β-amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J Neurosci 1992; 12: 376-389.
    • (1992) J Neurosci , vol.12 , pp. 376-389
    • Mattson, M.P.1    Cheng, B.2    Davis, D.3    Bryant, K.4    Lieberburg, I.5    Rydel, R.6
  • 37
    • 0026686938 scopus 로고
    • Commentary and perspective on studies of beta amyloid neurotoxicity
    • Yankner BA. Commentary and perspective on studies of beta amyloid neurotoxicity. Neurobiol Aging 1992; 13: 615-616.
    • (1992) Neurobiol Aging , vol.13 , pp. 615-616
    • Yankner, B.A.1
  • 38
    • 0029896354 scopus 로고    scopus 로고
    • Mechanisms of neuronal degeneration in Alzheimer's disease
    • Yankner BA. Mechanisms of neuronal degeneration in Alzheimer's disease. Neuron 1996; 16: 921-922.
    • (1996) Neuron , vol.16 , pp. 921-922
    • Yankner, B.A.1
  • 39
    • 0029076397 scopus 로고
    • Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid β-peptide
    • Yan SD, Yan SH, Chen X, Fu J, Chen M, Kuppusamy P, Smith M, Perry G, Godman G, Nawroth P, Zweier J, Stern D. Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid β-peptide. Nature Med 1995; 7: 693-699.
    • (1995) Nature Med , vol.7 , pp. 693-699
    • Yan, S.D.1    Yan, S.H.2    Chen, X.3    Fu, J.4    Chen, M.5    Kuppusamy, P.6    Smith, M.7    Perry, G.8    Godman, G.9    Nawroth, P.10    Zweier, J.11    Stern, D.12
  • 40
    • 0030607145 scopus 로고    scopus 로고
    • Enhancement of immunoreactivity for NF-κB in the hippocampal formation and cerebral cortex of Alzheimer's disease
    • Terai K, Matsuo A, McGeer PL. Enhancement of immunoreactivity for NF-κB in the hippocampal formation and cerebral cortex of Alzheimer's disease. Brain Res 1996; 735: 159-168.
    • (1996) Brain Res , vol.735 , pp. 159-168
    • Terai, K.1    Matsuo, A.2    McGeer, P.L.3
  • 41
    • 0025863618 scopus 로고
    • Neuropathological staging of Alzheimer-related changes
    • Braak H, Braak E. Neuropathological staging of Alzheimer-related changes. Acta Neuropathol 1991; 82: 239-259.
    • (1991) Acta Neuropathol , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 43
    • 0027434987 scopus 로고
    • Neurotoxicity of human amylin in rat primary hippocampal cultures: Similarities to Alzheimer's disease amyloid-beta neurotoxicity
    • May PC, Boggs LN, Fuson KS. Neurotoxicity of human amylin in rat primary hippocampal cultures: similarities to Alzheimer's disease amyloid-beta neurotoxicity. J Neurochem 1993; 61: 2330-2333.
    • (1993) J Neurochem , vol.61 , pp. 2330-2333
    • May, P.C.1    Boggs, L.N.2    Fuson, K.S.3
  • 44
    • 0028303844 scopus 로고
    • Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus
    • Lorenzo A, Razzaboni B, Weir C, Yankner BA. Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus. Nature 1994; 368: 756-750.
    • (1994) Nature , vol.368 , pp. 756-1750
    • Lorenzo, A.1    Razzaboni, B.2    Weir, C.3    Yankner, B.A.4
  • 46
    • 0030912540 scopus 로고    scopus 로고
    • Activation of NF-κB transcription factor is a common molecular signal in cell death induced by β-amyloid, amylin and hydrogen peroxide
    • Lezoualc'h F, Behl C. Activation of NF-κB transcription factor is a common molecular signal in cell death induced by β-amyloid, amylin and hydrogen peroxide. Alzheimer's Research 1997; 3: 43-50.
    • (1997) Alzheimer's Research , vol.3 , pp. 43-50
    • Lezoualc'h, F.1    Behl, C.2
  • 47
    • 0028889739 scopus 로고
    • Stimulation of ionotropic glutamate receptors activates transcription factor NF-κB in primary cultures
    • Kaltschmidt T, C, Kaltschmidt B, Baeuerle P. Stimulation of ionotropic glutamate receptors activates transcription factor NF-κB in primary cultures. Proc Natl Acad Sci USA 1995; 92: 9618-9622.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9618-9622
    • Kaltschmidt, T.C.1    Kaltschmidt, B.2    Baeuerle, P.3
  • 48
    • 0024093449 scopus 로고
    • Glutamate toxicity and diseases of the nervous sytem
    • Choi DW. Glutamate toxicity and diseases of the nervous sytem. Neuron 1988; 1: 623-634.
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi, D.W.1
  • 49
    • 0027686249 scopus 로고
    • Oxidative stress, glutamate, and neurodegenerative disorders
    • Coyle JT, Puttfarcken P. Oxidative stress, glutamate, and neurodegenerative disorders. Science 1993; 262: 689-695.
    • (1993) Science , vol.262 , pp. 689-695
    • Coyle, J.T.1    Puttfarcken, P.2
  • 50
    • 0030017136 scopus 로고    scopus 로고
    • Seizure activity results in a rapid induction of nuclear factor-κB in adult but not juvenile rat limbic structures
    • Rong Y, Baudry M. Seizure activity results in a rapid induction of nuclear factor-κB in adult but not juvenile rat limbic structures. J Neurochem 1996; 67: 662-668.
    • (1996) J Neurochem , vol.67 , pp. 662-668
    • Rong, Y.1    Baudry, M.2
  • 51
    • 0029976817 scopus 로고    scopus 로고
    • An essential role for NF-κB in preventing TNF-α-induced cell death
    • Beg AA, Baltimore D. An essential role for NF-κB in preventing TNF-α-induced cell death. Science 1996; 274: 782-784.
    • (1996) Science , vol.274 , pp. 782-784
    • Beg, A.A.1    Baltimore, D.2
  • 52
    • 0029858387 scopus 로고    scopus 로고
    • TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-κB
    • Wang CY, Mayo MW, Baldwin AS Jr. TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB. Science 1996; 274: 784-787.
    • (1996) Science , vol.274 , pp. 784-787
    • Wang, C.Y.1    Mayo, M.W.2    Baldwin Jr., A.S.3
  • 54
    • 0030298294 scopus 로고    scopus 로고
    • Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death
    • Liu ZG, Hsu HL, Goeddel DV, Karin M. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death. Cell 1996; 87: 565-576.
    • (1996) Cell , vol.87 , pp. 565-576
    • Liu, Z.G.1    Hsu, H.L.2    Goeddel, D.V.3    Karin, M.4
  • 55
    • 0028025563 scopus 로고
    • Apoptosis in cancer therapy: Crossing the threshold
    • Fisher DE. Apoptosis in cancer therapy: crossing the threshold. Cell 1994; 78: 539-542.
    • (1994) Cell , vol.78 , pp. 539-542
    • Fisher, D.E.1
  • 56
    • 0029799831 scopus 로고    scopus 로고
    • Neuroprotection by aspirin and sodium salicylate through blockade of NF-κB activation
    • Grilli M, Pizzi M, Memo M, Spano P. Neuroprotection by aspirin and sodium salicylate through blockade of NF-κB activation. Science 1996; 274: 1383-1385.
    • (1996) Science , vol.274 , pp. 1383-1385
    • Grilli, M.1    Pizzi, M.2    Memo, M.3    Spano, P.4
  • 57
    • 0028971169 scopus 로고
    • 17-β estradiol protects neurons from oxidative stress-induced cell death in vitro
    • Behl C, Widmann M, Trapp T, Holsboer F. 17-β estradiol protects neurons from oxidative stress-induced cell death in vitro. Biochem Biophys Res Commun 1995; 216: 473-482.
    • (1995) Biochem Biophys Res Commun , vol.216 , pp. 473-482
    • Behl, C.1    Widmann, M.2    Trapp, T.3    Holsboer, F.4
  • 59
    • 0030222080 scopus 로고    scopus 로고
    • Induction of neuroprotective κB-dependent transcription by secreted forms of the Alzheimer's β-amyloid precursor
    • Barger SW, Mattson MP. Induction of neuroprotective κB-dependent transcription by secreted forms of the Alzheimer's β-amyloid precursor. Mol Brain Res 1996; 40: 116-126.
    • (1996) Mol Brain Res , vol.40 , pp. 116-126
    • Barger, S.W.1    Mattson, M.P.2
  • 60
    • 0027478347 scopus 로고
    • Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein
    • Mattson MP, Cheng B, Culwell AR, Esch FS, Lieberburg I, Rydel R. Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein. Neuron 1993; 10: 243-254.
    • (1993) Neuron , vol.10 , pp. 243-254
    • Mattson, M.P.1    Cheng, B.2    Culwell, A.R.3    Esch, F.S.4    Lieberburg, I.5    Rydel, R.6
  • 61
    • 0027421474 scopus 로고
    • The expression of amyloid beta protein precursor protects nerve cells from β-amyloid and glutamate toxicity and alters their interaction with the extracellular matrix
    • Schubert D, Behl C. The expression of amyloid beta protein precursor protects nerve cells from β-amyloid and glutamate toxicity and alters their interaction with the extracellular matrix. Brain Res 1993; 629: 275-282.
    • (1993) Brain Res , vol.629 , pp. 275-282
    • Schubert, D.1    Behl, C.2
  • 62
    • 0028972237 scopus 로고
    • Identification and characterisation of a κB/Rel binding site in the regulatory region of the APP gene
    • Grilli M, Ribola M, Alberici A, Valerio A, Memo M, Spano P. Identification and characterisation of a κB/Rel binding site in the regulatory region of the APP gene. J Biol Chem 1995; 270: 26774-26777.
    • (1995) J Biol Chem , vol.270 , pp. 26774-26777
    • Grilli, M.1    Ribola, M.2    Alberici, A.3    Valerio, A.4    Memo, M.5    Spano, P.6
  • 63
    • 0029666276 scopus 로고    scopus 로고
    • Interleukin-1β and glutamate activate the NF-κB/Rel binding site from the regulatory region of the amyloid precursor protein gene in primary neuronal culture
    • Grilli M, Goffi F, Memo M, Spano P. Interleukin-1β and glutamate activate the NF-κB/Rel binding site from the regulatory region of the amyloid precursor protein gene in primary neuronal culture. J Biol Chem 1996; 271: 15002-15007.
    • (1996) J Biol Chem , vol.271 , pp. 15002-15007
    • Grilli, M.1    Goffi, F.2    Memo, M.3    Spano, P.4
  • 64
    • 0029906617 scopus 로고    scopus 로고
    • Regulation of Nerve Growth Factor mRNA by Interleukin-1 in rat hippocampal astrocytes is mediated by NF-κB
    • Friedman WJ, Thakur S, Seidman L, Rabson AB. Regulation of Nerve Growth Factor mRNA by Interleukin-1 in rat hippocampal astrocytes is mediated by NF-κB. J Biol Chem 1996; 271: 31115-31120.
    • (1996) J Biol Chem , vol.271 , pp. 31115-31120
    • Friedman, W.J.1    Thakur, S.2    Seidman, L.3    Rabson, A.B.4
  • 65
    • 0026780218 scopus 로고
    • Cytokine regulation of interleukin-6 gene expression in astrocytes involves activation of an NF-κB-like nuclear protein
    • Sparacio SM, Zhang Y, Vilcek J, Benveniste EN. Cytokine regulation of interleukin-6 gene expression in astrocytes involves activation of an NF-κB-like nuclear protein. J Neuroimmunol 1992; 39: 231-242.
    • (1992) J Neuroimmunol , vol.39 , pp. 231-242
    • Sparacio, S.M.1    Zhang, Y.2    Vilcek, J.3    Benveniste, E.N.4
  • 66
    • 0031022142 scopus 로고    scopus 로고
    • Janus faces of NF-κB: Neurodestruction versus neuroprotection
    • Lipton SA. Janus faces of NF-κB: neurodestruction versus neuroprotection. Nature Med 1997; 3: 20-22.
    • (1997) Nature Med , vol.3 , pp. 20-22
    • Lipton, S.A.1
  • 67
    • 0028785523 scopus 로고
    • Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-κB
    • Lin KI, Lee SH, Narayanan R, Baraban JM, Hardwick JM, Ratan RR. Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-κB. J Cell Biol 1995; 131: 1149-1161.
    • (1995) J Cell Biol , vol.131 , pp. 1149-1161
    • Lin, K.I.1    Lee, S.H.2    Narayanan, R.3    Baraban, J.M.4    Hardwick, J.M.5    Ratan, R.R.6
  • 68
    • 0027970546 scopus 로고
    • Gene expression and function of interleukin 1, interleukin 6 and tumor necrosis factor in the brain
    • Schöbitz B, de Kloet ER, Holsboer F. Gene expression and function of interleukin 1, interleukin 6 and tumor necrosis factor in the brain. Prog Neurobiol 1994; 44: 397-432.
    • (1994) Prog Neurobiol , vol.44 , pp. 397-432
    • Schöbitz, B.1    De Kloet, E.R.2    Holsboer, F.3
  • 70
    • 0345704610 scopus 로고
    • Establishment of a noradrenergic clonal cell line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
    • Greene LA, Tischler AS. Establishment of a noradrenergic clonal cell line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci USA 1976; 73: 2424-2428.
    • (1976) Proc Natl Acad Sci USA , vol.73 , pp. 2424-2428
    • Greene, L.A.1    Tischler, A.S.2
  • 71
    • 0030030030 scopus 로고    scopus 로고
    • Increased antioxidant enzyme activity in amyloid β protein-resistant cells
    • Sagara Y, Dargusch R, Klier FG, Schubert D, Behl C. Increased antioxidant enzyme activity in amyloid β protein-resistant cells. J Neurosci 1996; 16: 497-505.
    • (1996) J Neurosci , vol.16 , pp. 497-505
    • Sagara, Y.1    Dargusch, R.2    Klier, F.G.3    Schubert, D.4    Behl, C.5
  • 72
    • 0030009712 scopus 로고    scopus 로고
    • Oxidative stress-resistant cells are protected against haloperidol toxicity
    • Behl C, Lezoualc'h F, Widmann M, Rupprecht R, Holsboer F. Oxidative stress-resistant cells are protected against haloperidol toxicity. Brain Res 1996; 717: 193-195.
    • (1996) Brain Res , vol.717 , pp. 193-195
    • Behl, C.1    Lezoualc'h, F.2    Widmann, M.3    Rupprecht, R.4    Holsboer, F.5
  • 73
    • 0029416836 scopus 로고
    • Haloperidol-induced cell death - Mechanism and protection with vitamin E in vitro
    • Behl C, Rupprecht R, Skutella T, Holsboer F. Haloperidol-induced cell death - mechanism and protection with vitamin E in vitro. Neuroreport 1995; 7: 360-364.
    • (1995) Neuroreport , vol.7 , pp. 360-364
    • Behl, C.1    Rupprecht, R.2    Skutella, T.3    Holsboer, F.4
  • 74
    • 0028879819 scopus 로고
    • Role of transcriptional activation of IκB in mediation of immunnsuppression by glucocorticoids
    • Scheinman RI, Cogswell PC, Lofquist AK, Baldwin AS Jr. Role of transcriptional activation of IκB in mediation of immunnsuppression by glucocorticoids. Science 1995; 270: 283-286.
    • (1995) Science , vol.270 , pp. 283-286
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3    Baldwin Jr., A.S.4
  • 75
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of IκB synthesis
    • Auphan N, DiDonato JA, Rosette C, Helmberg A, Karin M. Immunosuppression by glucocorticoids: inhibition of NF-κB activity through induction of IκB synthesis. Science 1995; 270: 286-290.
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, N.1    Didonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 76
    • 0031024098 scopus 로고    scopus 로고
    • Glucocorticoids enhance oxidative stress-induced cell death in hippocampal neurons in vitro
    • Behl C, Lezoualc'h F, Trapp T, Widmann M, Skutella T, Holsboer F. Glucocorticoids enhance oxidative stress-induced cell death in hippocampal neurons in vitro. Endocrinology 1997; 138: 101-106.
    • (1997) Endocrinology , vol.138 , pp. 101-106
    • Behl, C.1    Lezoualc'h, F.2    Trapp, T.3    Widmann, M.4    Skutella, T.5    Holsboer, F.6
  • 77
    • 0031025302 scopus 로고    scopus 로고
    • Inhibition of nuclear factor kappa B (NF-κB) activity induces nerve growth factor-resistant apoptosis in PC12 cells
    • Taglialatela G, Robinson R, Perez-Polo JR. Inhibition of nuclear factor kappa B (NF-κB) activity induces nerve growth factor-resistant apoptosis in PC12 cells. J Neurosci Res 1997; 47: 155-162.
    • (1997) J Neurosci Res , vol.47 , pp. 155-162
    • Taglialatela, G.1    Robinson, R.2    Perez-Polo, J.R.3
  • 78
    • 0028814951 scopus 로고
    • Calretinin-immunoreactive neurons are resistant to β-amyloid toxicity in vivo
    • Pike CJ, Cotman CW. Calretinin-immunoreactive neurons are resistant to β-amyloid toxicity in vivo. Brain Res 1995; 671: 293-298.
    • (1995) Brain Res , vol.671 , pp. 293-298
    • Pike, C.J.1    Cotman, C.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.